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Autor:
Canan Yildirim, Yesim Coskun
Publikováno v:
International Journal of Neuroscience. 133:322-326
Despite the development of new antiseizure drugs (ASDs), around one third of epilepsy patients become refractory to treatment or experience adverse events due to ASDs. Therefore, discovery of new ASDs and new therapy options are crucial to improve th
Publikováno v:
Expert Opinion on Investigational Drugs. 30:1125-1140
Introduction Due to new insights into the pathogenesis of inflammatory myopathies -in short myositis- and the urgent need for new treatment options in patients who are refractory to standard therapy, multiple novel drugs have been developed and studi
Publikováno v:
Current Eye Research. 46:1792-1799
PURPOSE To evaluate whether allergic conjunctivitis (AC) could be induced by Acanthamoeba excretory-secretory protein (ESP) and analyze the therapeutic effect of resolvin (Rv) D1 and antiallergic agents. METHODS Human conjunctival epithelial cells (H
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2105-2111
Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce blood glucose and glycosylated haemoglobin (HbA1c), the risk of hospitalization for heart failure (HF) and the incidence of serious adverse kidney function events (chronic kidney
Publikováno v:
Ocular Immunology and Inflammation. 30:1625-1632
Introduction: Didanosine is an adenosine analog, part of the nucleoside reverse-transcriptase inhibitor family. Since the description of didanosine-induced retinopathy in the early 1990s, little is known about the progression of this toxic retinopath
Autor:
Andriana M. Bukonjić, Miloš N. Milosavljević, Jovana Z Milosavljević, Ivo Božović, Dragana Lavrnic, Srđan Stefanović, Stojan Peric, Slobodan M. Jankovic, Dejan Aleksic
Publikováno v:
Neurological Research. 43:1023-1030
OBJECTIVES Our aim was to determine risk factors for and frequency of potential drug-drug interactions (pDDIs) among hospitalized patients with myasthenia gravis (MG). METHODS This was a retrospective cross-sectional study of the-first time hospitali
Publikováno v:
Expert Review of Neurotherapeutics. 21:755-778
Introduction: Nabiximols, a cannabinoid-based oromucosal spray, is indicated as add-on therapy for symptomatic relief of spasticity in persons with multiple sclerosis (MS). This review compiles tol...
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2199-2220
Given the relationship between the pathogenesis of obesity and type 2 diabetes mellitus (T2DM) as well as their significant health consequences, treatment strategies that can induce weight loss while achieving glycemic control are needed. Novel weigh
Autor:
Åke SjöholmÅke Sjöholm
Publikováno v:
Expert Opinion on Pharmacotherapy. 22:2143-2148
Introduction: Insulin and its analogues have so far been the only approved treatment for type 1 diabetes in Europe, while in the US, the amylin analog pramlintide is approved for adjuvant use with ...
Autor:
Gabriella Silvestri, Benedetta Burattini, Nicola Montano, Alessia Perna, Marco Gessi, Fabio Papacci, Giovanni Pennisi
Publikováno v:
British Journal of Neurosurgery. :1-4
Leptomeningeal carcinomatosis (LC) is defined as infiltration of the leptomeninges by metastatic carcinoma and often represents the end stage of cancer disease. In breast cancer, LC is associated with a median survival of approximately 6-8 weeks with