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Publikováno v:
Current Medical Research and Opinion. 32:1087-1096
Objective To evaluate glycemic control among patients with type 2 diabetes mellitus (T2DM) treated with canagliflozin (CANA) vs. dipeptidyl peptidase-4 (DPP-4) inhibitors. Methods Using integrated claims and lab data from a US health plan of commerci
Publikováno v:
Current Medical Research and Opinion. 31:2273-2285
To assess the efficacy of fenofibrate and statin dual therapy versus a double or equivalent dose of statin monotherapy.A systematic literature search and meta-analysis was performed for publications before 1 January 2014 in MEDLINE, Embase, and BIOSI
Autor:
H. R. Salkar, Rajesh Khyalappa, Mahendra Parmar, Anil Pareek, Manish Agarwal, R. Legha, Urman Dhruv, Navneet Agrawal, Nitin Chandurkar, N. K. Thulaseedharan, Vikas Pai, Usha Sriram, S. Mathur, Subhash Saxena, Sangeeta Pednekar
Publikováno v:
Current Medical Research and Opinion. 31:2105-2117
To evaluate the efficacy and safety of atorvastatin + hydroxychloroquine fixed-dose combination tablets in comparison with atorvastatin alone in treatment of dyslipidemia.This double-blind, randomized, out-patient study was conducted in 328 patients
Publikováno v:
Current Medical Research and Opinion. 31:1919-1931
There is no clear consensus regarding treatment of patients with type 2 diabetes mellitus (T2DM) that is inadequately controlled using dual combination therapy. Recommended agents for triple combination therapy should have complementary mechanisms of
Autor:
Thomas Blevins
Publikováno v:
Expert Opinion on Drug Safety. 14:789-793
Introduction: For patients with type 2 diabetes mellitus (T2DM), there is a growing interest in sodium glucose co-transporter 2 (SGLT2) inhibitors, a class of glucose-lowering agents that act independently of insulin secretion and insulin action and
Autor:
Benjamin Chavez, Mary Barna Bridgeman
Publikováno v:
Expert Opinion on Pharmacotherapy. 16:395-398
Gout is a rheumatologic condition associated with elevated serum uric acid levels and deposition of monosodium urate crystals in joints and soft tissues. The xanthine oxidase inhibitor, allopurinol, has historically been the principle agent utilized
Autor:
Nicola Dalbeth, Philip Robinson
Publikováno v:
Expert Opinion on Pharmacotherapy. 16:533-546
Gout is a common inflammatory arthritis affecting almost 6% of US males and 2% of US females. The central cause of gout is deposition of monosodium urate crystals, and the focus of treatment is aimed at crystal dissolution using urate-lowering therap
Autor:
Giampaolo Merlini, Laura Obici
Publikováno v:
Expert Opinion on Investigational Drugs. 23:1239-1251
Transthyretin (TTR)-related hereditary amyloidosis is an adult-onset, dominantly inherited, systemic neurodegenerative disease endemic in some populations. Stabilization of the native structure of TTR by small-molecule ligands has recently proved eff
Publikováno v:
Current Medical Research and Opinion. 30:775-784
Statin treatment may impair glucose homeostasis and increase the risk of new-onset diabetes mellitus, although this may depend on the statin, dose and patient population. We evaluated the effects of pitavastatin 4 mg/day on glucose homeostasis in pat
Publikováno v:
Current Medical Research and Opinion. 30:223-228
To investigate the distribution of statin therapy correlated gene polymorphism allele CYP2D6*10 (C188T) in Ningxia Hui nationality and to discuss the relationship between the gene polymorphism allele CYP2D6*10 (C188T) and the lipid-lowering efficacy