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pro vyhledávání: '"Gregory B Lesinski"'
Autor:
Kristin Wilson, Jennifer Yang, Tanios Bekaii-Saab, Omar Elnaggar, Michael C. Ostrowski, Gregory B. Lesinski, Gregory S. Young, Reena Shakya, Jason R. Pitarresi, Hannah M. Komar, Thomas Ludwig, Mark Bloomston, Thomas A. Mace
Publikováno v:
Oncotarget
The Jak/STAT pathway is activated in human pancreatic ductal adenocarcinoma (PDAC) and cooperates with mutant Kras to drive initiation and progression of PDAC in murine models. We hypothesized that the small-molecule Jak2 inhibitor (BMS-911543) would