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Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-18
Brevilin A (BA), a sesquiterpene lactone isolated from Centipeda minima herb, has been identified to exhibit potent anticancer activity. However, the potential pharmacological effect and mechanism of BA in regulating endothelial cell (EC) angiogenesi
Autor:
Zijian Zheng, Shushan Zhang, Hanwen Zhang, Zhongzheng Gao, Xiangrong Wang, Xinjie Liu, Cheng Xue, Longping Yao, Guohui Lu
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-20
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder that manifests as motor and nonmotor symptoms due to the selective loss of midbrain DArgic (DA) neurons. More and more studies have shown that pathological reactions initiated by au
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-39
Adaptin ear-binding coat-associated protein 2 (NECAP2) belongs to the family of proteins encoding adaptin-ear-binding coat-associated proteins. However, its immune effect on tumors and its microenvironment are still unclear. Here, we systematically e
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-25
The liver is the largest digestive organ in the human body. The increasing incidence of chronic liver fibrosis is one of the major health challenges in the world. Liver fibrosis is a wound-healing response to acute or chronic cellular damage of liver
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-14
Peripheral nerve injury (PNI) is a major clinical problem that may lead to different levels of sensory and motor dysfunction including paralysis. Due to the high disability rate and unsatisfactory prognosis, the exploration and revealment of the mech
Autor:
Fatemeh Forouzanfar, Mohammadreza Ahmadpoor, Mostafa Moshirian Farahi, Ali Hadianfar, Amirhossein Sahebkar, Habibollah Esmaily, Mohsen Nematy, Hassan Rakhshandeh
Publikováno v:
Mediators of Inflammation. 2022:1-10
Introduction. COVID-19, an epidemic of coronavirus infection, has become a major global threat. The coronavirus mainly targets the human respiratory system, followed by cytokine storm, and altered immune responses associated with disease progression
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-16
Background. Benign essential blepharospasm (BEB) is a form of focal dystonia that causes excessive involuntary spasms of the eyelids. Currently, the pathogenesis of BEB remains unclear. This study is aimed at investigating the serum metabolites profi
Publikováno v:
Mediators of Inflammation. 2022:1-10
Background and Aims. Mean platelet volume to platelet count ratio (MPV/PC) has been found to be an independent risk factor for mortality in various diseases, including cardiovascular disease, cancer, and hemodialysis. We aimed to evaluate the associa
Publikováno v:
Mediators of Inflammation. 2022:1-13
This study is aimed at investigating the role of β-galactoside-α2,3-sialyltransferase III (ST3GAL3) in fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA), as well as its potential mechanism of action. The Gene Expression Omnibus (GEO)
Autor:
Linbin Zhou, Jing Na He, Lin Du, Bo Man Ho, Danny Siu-Chun Ng, Poemen P. Chan, Clement C. Tham, Chi Pui Pang, Wai Kit Chu
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-9
Primary open-angle glaucoma (POAG) is the most common form of glaucoma, for which elevated intraocular pressure (IOP) is a major risk factor. IOP is mainly regulated by dynamic balance of aqueous humor (AH) production and outflow via the conventional