Zobrazeno 1 - 10
of 39
pro vyhledávání: ''
Autor:
Zeinab Albadry M. Zahran, Khalid Muhammad, Alaa Rashad, Zeinab A Abd Elhameed, Yasir Waheed, Salah M. Khallaf, Gaber El-Saber Batiha, Amal Rayan, Dalia O. Mohamed, Hanaa Nafady-Hego, Helal F Hetta, Asmaa M Zahran
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research
Journal of Immunology Research
Background and Aim. Myeloid-derived suppressor cells (MDSCs) contribute to the process of malignant transformation and tumor progression through immuno- and nonimmunosuppressive mechanisms. The current study is aimed at providing the predictive and p
Autor:
Wenjie Gao, Bo Gao, Xianjian Qiu, Dongsheng Huang, Jincheng Qiu, Pengfei Li, Hang Zhou, Zhancheng Liang, Zhihuai Deng, Wenjun Hu, Tongzhou Liang, Anjing Liang, Shaoguang Li, Taiqiu Chen
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2021 (2021)
Mediators of Inflammation, Vol 2021 (2021)
Intervertebral disc degenerative disease (IDD) is the most common degenerative spine disease, which leads to chronic low back pain and symptoms in the lower extremities. In this study, we found that RORα, a member of the retinoid-related orphan rece
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research
Journal of Immunology Research
Background. Preoperative chemoradiotherapy (pCRT) is a common and essential therapeutic strategy for patients with locally advanced rectal cancer (LARC), but poor tumor response and therapeutic resistance to chemoradiotherapy have appeared usually am
Autor:
Xiubao Ren, Lanfang Li, Tianyuan Ren, Zheng Song, Zhengzi Qian, Huilai Zhang, Xianhuo Wang, Jin He, Lihua Qiu, Tingting Zhang, Qiongli Zhai, Shiyong Zhou, Xianming Liu, Jing Zhao, Bin Meng, Lei Jiao, Zhenzhen Zhang
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Journal of Immunology Research
Journal of Immunology Research
Tim-3 is a promising target for antitumor immunotherapy. A number of clinical trials are evaluating the efficacy of anti-Tim-3 therapies as a single agent or combinations in solid tumors and haematologic malignancies. However, there remains a conside
Autor:
Alin Rauta, Gabriela Turcu, Cristian Mogodici, Liana Sticlaru, Daniela Georgescu, Cristiana Popp, Mirela Cioplea, Alexandra Cioroianu, Roxana Ioana Nedelcu, Sabina Zurac, Luciana Nichita
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2020 (2020)
Journal of Immunology Research, Vol 2020 (2020)
Cutaneous melanoma is a significant immunogenic tumoral model, the most frequently described immune phenomenon being tumor regression, as a result of the interaction of tumoral antigens and stromal microenvironment. We present a retrospective cohort
Autor:
Lucero Adriana Salazar Salas, Ana Elena Peredo Escárcega, Gabriela Fonseca Camarillo, Emilio Iturriaga Goyon, Rafael Barreto Zuñiga, Jesús K. Yamamoto-Furusho
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Mediators of Inflammation
Mediators of Inflammation
Background. Multiple genes have been associated with IBD, and many of these can be linked to alterations in autophagy, UPR, ubiquitination, and metabolic and immune response pathways. The aim of this study was to analyze a transcriptomic panel of med
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2019 (2019)
Mediators of Inflammation, Vol 2019 (2019)
Background. Atherosclerosis (AS) is recognized as a chronic inflammatory disease. It is caused by the interaction between inflammatory cells such as macrophages, dendritic cells, and lipoproteins. Evidence has revealed that macrophage pyroptosis in l
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research
Journal of Immunology Research
Tumor-infiltrating immune cells are capable of effective cancer surveillance, and their abundance is linked to better prognosis in numerous tumor types. However, in uveal melanoma (UM), extensive immune infiltrate is associated with poor survival. Th
Autor:
Liyun Wu, Jingling Tang, Xinjun Wang, Hua Zhang, Hang Du, Yuan Yang, Pingsheng Hu, Xiaoyun Li, Ruyi Zhang
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research
Journal of Immunology Research
Purpose. This study is aimed at immunologically characterizing sentinel lymph nodes (SNs) in colorectal cancer (CRC) patients and identifying changes in immunological phenotype and function of SNs isolated from the tumor immunosuppressive microenviro
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research
Journal of Immunology Research
Background. Increasing evidence suggests that microRNAs (miRNAs) are involved in genome instability (GI) and drive the occurrence of tumors. However, the role of GI-related miRNAs in gastric cancer (GC) remains largely unknown. Herein, we developed a