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Autor:
Xiaozhi Li, Yutong Meng
Publikováno v:
BioMed Research International, Vol 2020 (2020)
BioMed Research International
BioMed Research International
Introduction. Glioblastoma is the most malignant grade of glioma, and it is also the most common primary tumor in the brain. Immunotherapy is a kind of precise tumor treatment. However, there are limited studies about immune-related lncRNA. This stud
Autor:
Xi Chen, Yongwei Yu, Yinghao Sun, Jingyi He, Fei Guo, Xin Lu, Zhi Cao, Yalong Xu, Huan Xu, Fubo Wang, Jin Ji
Publikováno v:
Disease Markers
Disease Markers, Vol 2020 (2020)
Disease Markers, Vol 2020 (2020)
Backgrounds. Fatty acid synthase (FASN) has been regarded as a prognostic marker in prostate cancer (PCa). In this study, we evaluated FASN expression at both mRNA and protein levels and assessed the association between FASN expression and prognosis
Publikováno v:
Disease Markers, Vol 2021 (2021)
Disease Markers
Disease Markers
The tight relationship between ferroptotic cell death and immune response demonstrated by recent studies enlightened us to detect the underlying roles of ferroptosis-related long noncoding RNAs (frlncRNAs) in the tumor microenvironment of bladder can
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Journal of Immunology Research
Journal of Immunology Research
Background. Increasing evidence suggests that microRNAs (miRNAs) are involved in genome instability (GI) and drive the occurrence of tumors. However, the role of GI-related miRNAs in gastric cancer (GC) remains largely unknown. Herein, we developed a
Publikováno v:
BioMed Research International, Vol 2020 (2020)
BioMed Research International
BioMed Research International
Nonluminal breast cancer has high early metastasis and treatment resistance, and neoadjuvant chemotherapy (NAC) is needed. The presence of cancer stem cells (CSC) and epithelial-mesenchymal transition (EMT) leads to poor prognosis. This study investi
Autor:
Alexander Quaas, Hakan Alakus, Max Kraemer, Arnulf H. Hoelscher, Christiane Bruns, Wolfgang Schröder, Heike Loeser, Reinhard Buettner, Thomas Zander, Philipp Lohneis, Florian Gebauer
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Journal of Immunology Research
Journal of Immunology Research
Background. Indoleamine 2,3-dioxygenase (IDO) is an interferon-inducible immune checkpoint expressed on tumor-infiltrating lymphocytes (TILs). IDO is known as a poor prognostic marker in esophageal squamous cell cancer, while a positive effect was sh
Autor:
Teng Aik Ong, Glenda C. Gobe, Ning Yi Yap, Komathi Perumal, K. Mun, Azad Hassan Abdul Razack, Shanggar Kuppusamy, Retnagowri Rajandram
Publikováno v:
BioMed Research International, Vol 2020 (2020)
BioMed Research International
BioMed Research International
Background. The mechanisms that link obesity and cancer development are not well-defined. Investigation of leptin and leptin receptor expressions may help define some of the mechanisms. These proteins are known for associating with the immune respons
Publikováno v:
Disease Markers, Vol 2020 (2020)
Disease Markers
Disease Markers
Background. Degradation of the extracellular matrix (ECM), an essential step in tumour invasion and metastasis, is mainly dependent on the activities of both matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). This s
Autor:
Haishan Zhao, Huizhe Wu, Enhua Wang, Yong Liu, Hui Kang, Minjie Wei, Qinghuan Xiao, Weifan Yao
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
The genetic variants of the ATP-binding cassette, subfamily G, member 2 (ABCG2) are known to be involved in developing cancer risk and interindividual differences in chemotherapeutic response. The polymorphisms inABCG2gene were genotyped by using PCR
Autor:
Daniel Winardi, Ching Liang Hsieh, Chee Yin Chai, Joon Khim Loh, Chia Li Chung, Hung Pei Tsai, Yung-Hsiang Chen
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2014 (2014)
BioMed Research International, Vol 2014 (2014)
Glioblastoma multiforme is one of the most serious malignant brain tumors and is characterized by resistance to chemotherapy and radiation therapy. Recent studies suggest that autophagy may play an important role not only in the regulation of cancer