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Publikováno v:
BioMed Research International, Vol 2021 (2021)
Background. Colorectal cancer (CRC) is recognized as one of the most common malignancies with a high mortality rate worldwide, supporting the necessity for an effective novel antitumor drug to improve current therapy’s effectiveness. Substance P (S
Publikováno v:
Gastroenterology Research and Practice, Vol 2021 (2021)
Gastroenterology Research and Practice
Gastroenterology Research and Practice
Purpose. Hepatocellular carcinoma (HCC) accounts for approximately ninety percent of primary liver cancer. This study attempted to investigate the effects of the long noncoding RNA MIR100HG (MIR100HG) in HCC and the underlying molecular mechanism. Ma
Autor:
Sang Kyum Kim, Ji Hye Im, Suntae Kim, Wankyu Kim, Sun Jo Kim, Young Jae Choi, Ji-Yoon Lee, Sung Won Kwon, Keon Wook Kang
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Background. Although the efficacy of epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR- TKI) therapy has been proven in non-small cell lung cancer (NSCLC) patients, acquired resistance to EGFR-TKIs presents a serious clinical problem.
Autor:
Ahmad Shanei, Mahsa Mansourian
Publikováno v:
BioMed Research International, Vol 2021 (2021)
BioMed Research International
BioMed Research International
Pulsed electromagnetic field (PEMF) therapy is a type of physical stimulation that affects biological systems by producing interfering or coherent fields. Given that cell types are significantly distinct, which represents an important factor in stimu
Autor:
Jiang-Rong Zhou, Rui Jian, Hao Zhang, Yun Xu, Jun-Qiao Li, Qiu-Han Chen, Jun-Chen Li, Fang Lu
Publikováno v:
Gastroenterology Research and Practice
Gastroenterology Research and Practice, Vol 2021 (2021)
Gastroenterology Research and Practice, Vol 2021 (2021)
Background. KLF4 and KLF5 are members of the KLF transcription factor family, which play an important role in many gastrointestinal tumors. To gain a deeper insight into its function and role, bioinformatics was used to analyze the function and role
Publikováno v:
Journal of Oncology, Vol 2021 (2021)
Journal of Oncology
Journal of Oncology
Purpose. Radiotherapy has been widely applied for the treatment of locally advanced and metastatic gastric adenocarcinoma (GAC). The aberrant expression of secreted phosphoprotein 1 (SPP1) is involved in radiosensitivity in a variety of cancers. The
Publikováno v:
Journal of Oncology, Vol 2021 (2021)
Journal of Oncology
Journal of Oncology
Background. Propofol is an anesthetic commonly used clinically and has been found to have antitumor activity in various cancers. The purpose of this study was to investigate the role of propofol in hepatoblastoma (HB). Methods. CCK-8 and transwell we
Publikováno v:
Disease Markers, Vol 2021 (2021)
Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. Currently, targeting therapy makes great advances for the treatment of TNBC, whereas more effective therapeutic targets are urgently needed. Cyclin B2 (CCNB2), which b
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
Background. Hepatocellular carcinoma (HCC) is the main form of primary liver cancer and is one of the most prevalent and life-threatening malignancies globally. Hypoxia activates hypoxia-inducible factor-1α (HIF-1α), which is the key factor in prom
Autor:
Gea Abigail Uy Ecoy, Hnin Ei Ei Khine, Pithi Chanvorachote, Anirut Hlosrichok, Boonchoo Sritularak, Chatchai Chaotham, Pornchanok Taweecheep, Eakachai Prompetchara
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
Cancer stem-like cells (CSCs) are key mediators driving tumor initiation, metastasis, therapeutic failure, and subsequent cancer relapse. Thus, targeting CSCs has recently emerged as a potential strategy to improve chemotherapy. In this study, the an