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Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2020 (2020)
Journal of Immunology Research, Vol 2020 (2020)
Immune imbalance and barrier destruction of intestinal mucosa are the central pathogenic factors of Crohn’s disease (CD). In this study, three independent microarray studies of CD were integrated and 9912 differentially expressed genes (DEGs) were
Autor:
Rui Wang, Peiyao Wu, Yuqing Yang, Lu Jiang, Peiyang Yuan, Shuhan Luo, Qi Han, Tao Zhou, Xuemei Qiu
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2020 (2020)
Mediators of Inflammation, Vol 2020 (2020)
Oral lichen planus (OLP) is a chronic inflammatory oral mucosal disorder mediated by T cells, with a multifactorial etiology. Hashimoto’s thyroiditis (HT) is a common autoimmune disease characterized by hypothyroidism. Although many clinical studie
Autor:
Patrick Sulzgruber, Alexander Niessner, Felix Hofer, Niema Kazem, Lorenz Koller, Andreas Hammer, Johann Wojta, Martin Hülsmann, Bernhard Richter, Steffen Blum
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Mediators of Inflammation
Mediators of Inflammation
Background. Heart failure with reduced ejection fraction (HFrEF) constitutes a global health issue. While proinflammatory cytokines proved to have a pivotal role in the development and progression of HFrEF, less attention has been paid to the cellula
Publikováno v:
Analytical Cellular Pathology (Amsterdam)
Analytical Cellular Pathology, Vol 2019 (2019)
Analytical Cellular Pathology, Vol 2019 (2019)
This study is aimed at investigating the lymphocyte subsets of cerebrospinal fluid (CSF) to provide possible differential diagnostic values and better understand the pathophysiological mechanism underlying autoimmune encephalitis (AE) and infectious
Autor:
Jaroslav Lindner, Helena Kratochvilova, Anna Cinkajzlová, Michal Lips, Michal Pořízka, Aneta Pierzynová, Milos Mraz, Martin Haluzik, Vojtěch Melenovský, Tomáš Kučera, Zdeňka Lacinová, Jana Klouckova, Ilja Stříž, Petr Kopecký
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2019 (2019)
Mediators of Inflammation, Vol 2019 (2019)
Immunocompetent cells including lymphocytes play a key role in the development of adipose tissue inflammation and obesity-related cardiovascular complications. The aim of the study was to explore the relationship between epicardial adipose tissue lym
Autor:
Abigail S. Marshall, Courtney A. Bannerman, Nader Ghasemlou, Ian Gilron, Jaqueline Raymondi Silva
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2019 (2019)
Journal of Immunology Research, Vol 2019 (2019)
Skin-resident γδ T cells play an important role in maintaining the immune barrier at the epithelial surface. Their roles in wound healing, regulation of immune response to injury, and reepithelialization have been characterized extensively in the m
Autor:
Keigo Nishida, Ryota Uchida
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research, Vol 2018 (2018)
Zinc is essential for maintaining normal structure and physiological function of cells. Its deficiency causes growth retardation, immunodeficiency, and neuronal degeneration. Zinc homeostasis is tightly regulated by zinc transporters and metallothion
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2018 (2018)
Mediators of Inflammation, Vol 2018 (2018)
Galectins areβ-galcotosid-binding lectins. The function of galectins varies with their tissue-specific and subcellular location, and their binding to carbohydrates makes them key players in several intra- and extracellular processes where they bind
Autor:
Xinmiao Wang, Xiaolin Tong, Qingwei Li, Han Wang, Yingying Yang, Lin Han, Yanwen Liu, Zezheng Gao, Haoran Wu, Linhua Zhao
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2018 (2018)
Mediators of Inflammation, Vol 2018 (2018)
Diabetes mellitus (DM) is one of the most familiar chronic diseases threatening human health. Recent studies have shown that the development of diabetes is closely related to an imbalance of the gut microbiota. Accordingly, there is increasing intere
Autor:
Jaehong Kim
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research, Vol 2018 (2018)
Recent findings show that the metabolic status of immune cells can determine immune responses. Metabolic reprogramming between aerobic glycolysis and oxidative phosphorylation, previously speculated as exclusively observable in cancer cells, exists i