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Publikováno v:
Disease Markers
Disease Markers, Vol 2021 (2021)
Disease Markers, Vol 2021 (2021)
Background:6-Phosphofructo-2-kinase/fructose-2,6-biphosphate-4 (PFKFB4) is a key factor that plays an important role in tumorigenesis. However, its role in triple-negative breast cancer (TNBC) progression needs to be further validated.We investigated
Publikováno v:
Disease Markers
Disease Markers, Vol 2021 (2021)
Disease Markers, Vol 2021 (2021)
Recent clinical trials of lung adenocarcinoma with immune checkpoint inhibitors revealed that lung adenocarcinoma patients with EGFR mutations have a poor response to immunotherapy. However, the mechanisms have not been addressed. We performed immuno
Autor:
Manman Wang, Xue Liang, Lijun Cheng, Pengjuan Xu, Jiageng Cai, Guangping Li, Xuewen Wang, Jiao Li
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2020 (2020)
BioMed Research International, Vol 2020 (2020)
Background. Our previous study demonstrated that the expression of miR-16 was downregulated in the cell and animal models of atherosclerosis (AS), a main contributor to coronary artery disease (CAD). Overexpression of miR-16 inhibited the formation o
Publikováno v:
Analytical Cellular Pathology (Amsterdam)
Analytical Cellular Pathology, Vol 2020 (2020)
Analytical Cellular Pathology, Vol 2020 (2020)
Purpose. To examine the expression of RAD51 in oral squamous cell carcinoma (OSCC) and analyze its connection with pathological grade, clinical stage, and lymphatic metastasis potential. Methods. For this study, 74 OSCC samples, 15 normal mucosa tiss
Publikováno v:
BioMed Research International, Vol 2020 (2020)
BioMed Research International
BioMed Research International
Purpose. CD147, also known as BSG, is a type I transmembrane glycoprotein that belonged to immunoglobulin superfamily. Mature CD147 is an N-linked glycosylated protein and exists on the transmembrane and as soluble forms in tumors. However, the funct
Publikováno v:
Analytical Cellular Pathology, Vol 2020 (2020)
Analytical Cellular Pathology (Amsterdam)
Analytical Cellular Pathology (Amsterdam)
Bladder cancer (BC) is one of the tumors which occur most frequently in urological system, but less is known about the expression of tight junction proteins and its clinical significance in BC. In this study, expression of claudin-4, zonula occludens
The Expression and Prognostic Value of FGF2, FGFR3, and FGFBP1 in Esophageal Squamous Cell Carcinoma
Autor:
Mengyan Li, Yuqing Ma, Hui Wang, Wenjing Zhang, Wenying Liu, Ya-Xing Zhou, Chao Li, Shanshan Xu
Publikováno v:
Analytical Cellular Pathology, Vol 2020 (2020)
Analytical Cellular Pathology (Amsterdam)
Analytical Cellular Pathology (Amsterdam)
Background. Esophageal squamous cell carcinoma was treated by operation and chemoradiotherapy. However, the prognosis of most patients is poor after treatment, and most studies have shown that FGF2 and its receptor (FGFR) are involved in the developm
Publikováno v:
BioMed Research International, Vol 2020 (2020)
BioMed Research International
BioMed Research International
Nasopharyngeal carcinoma (NPC) is a malignant tumor with poor prognosis, high morbidity, and mortality. Currently, immunocheckpoint therapy has led to new treatment strategies for almost all cancers, including nasopharyngeal carcinoma. Inducible T-ce
Publikováno v:
Disease Markers
Disease Markers, Vol 2020 (2020)
Disease Markers, Vol 2020 (2020)
Background. Insulin receptor substrate 1 (IRS-1) is an important molecule of the insulin signal transduction pathway and has been associated with the occurrence and development of many tumors, including hepatocellular carcinoma (HCC). Our study was d
Autor:
Liana Sticlaru, Mirela Cioplea, Cristiana Popp, Luciana Nichita, Florica Stăniceanu, Alexandra Bastian, Gianina Micu
Publikováno v:
Analytical Cellular Pathology (Amsterdam)
Analytical Cellular Pathology, Vol 2019 (2019)
Analytical Cellular Pathology, Vol 2019 (2019)
Chronic inflammation induced by Helicobacter pylori (H. pylori) infection plays a major role in development of gastric cancer. However, recent findings suggested that progression of inflammation and neoplastic transformation in H. pylori infection ar