Zobrazeno 1 - 10
of 199
pro vyhledávání: '"11"'
Autor:
Hyun-Jung Kim, Ali Al-Mourabit, Cristina Florean, Kyung Rok Kim, Byung Woo Han, Cécile Debitus, Mario Dicato, Marc Diederich, Michael Schnekenburger, Céline Moriou
Publikováno v:
Marine drugs
Marine drugs, MDPI, 2018, 16 (12), pp.518. ⟨10.3390/md16120518⟩
Marine Drugs
Volume 16
Issue 12
Marine drugs, 2018, 16 (12), pp.518. ⟨10.3390/md16120518⟩
Marine Drugs, Vol 16, Iss 12, p 518 (2018)
Marine Drugs (1660-3397) (Mdpi), 2018-12, Vol. 16, N. 12, P. 518 (19p.)
Marine drugs, MDPI, 2018, 16 (12), pp.518. ⟨10.3390/md16120518⟩
Marine Drugs
Volume 16
Issue 12
Marine drugs, 2018, 16 (12), pp.518. ⟨10.3390/md16120518⟩
Marine Drugs, Vol 16, Iss 12, p 518 (2018)
Marine Drugs (1660-3397) (Mdpi), 2018-12, Vol. 16, N. 12, P. 518 (19p.)
Treatment of acute myeloid leukemia (AML) patients is still hindered by resistance and relapse, resulting in an overall poor survival rate. Recently, combining specific B-cell lymphoma (Bcl)-2 inhibitors with compounds downregulating myeloid cell leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297fdc840a54db8c962da0cb240a700e
https://hal.archives-ouvertes.fr/hal-02339755/document
https://hal.archives-ouvertes.fr/hal-02339755/document
Autor:
Anne Davit-Spraul, Elodie Mareux, Martine Lapalus, Emmanuel Gonzales, Alice Thébaut, M. Almes, Emmanuel Jacquemin, Olivier Namy, Brigitte Grosse, Rachida Amzal, Laure Bidou, Mauricette Collado-Hilly
Publikováno v:
Hepatology
Hepatology, Wiley-Blackwell, 2020, ⟨10.1002/hep.31476⟩
Hepatology (Baltimore, Md.)
Hepatology, 2020, ⟨10.1002/hep.31476⟩
Hepatology, Wiley-Blackwell, 2020, ⟨10.1002/hep.31476⟩
Hepatology (Baltimore, Md.)
Hepatology, 2020, ⟨10.1002/hep.31476⟩
BACKGROUND AND AIMS Progressive familial intrahepatic cholestasis type 2 (PFIC2) is a severe hepatocellular cholestasis due to biallelic mutations in ABCB11 encoding the canalicular bile salt export pump (BSEP). Nonsense mutations are responsible for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d50805ea4c922cb12dc3cd13fed58fe
https://hal.archives-ouvertes.fr/hal-02907470
https://hal.archives-ouvertes.fr/hal-02907470
Autor:
Laurent Y. Alleman, Adil Ouali Alami, Corinne Gower-Rousseau, Madjid Djouina, Pierre Desreumaux, Mathilde Body-Malapel, Esperanza Perdrix, Cécile Vignal, Muriel Pichavant, Florian Dingreville, Christophe Waxin
Publikováno v:
Particle and Fibre Toxicology
Particle and Fibre Toxicology, 2017, 14 (1), pp.46. ⟨10.1186/s12989-017-0227-z⟩
Particle and Fibre Toxicology, BioMed Central, 2017, 14 (1), pp.46. ⟨10.1186/s12989-017-0227-z⟩
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-13 (2017)
ResearcherID
Particle and Fibre Toxicology, 2017, 14 (1), pp.46. ⟨10.1186/s12989-017-0227-z⟩
Particle and Fibre Toxicology, BioMed Central, 2017, 14 (1), pp.46. ⟨10.1186/s12989-017-0227-z⟩
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-13 (2017)
ResearcherID
Background Air pollution is a recognized aggravating factor for pulmonary diseases and has notably deleterious effects on asthma, bronchitis and pneumonia. Recent studies suggest that air pollution may also cause adverse effects in the gastrointestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cddbde5cbf6c8f82b6a47de4782979f
https://hal.science/hal-01935778/document
https://hal.science/hal-01935778/document
Autor:
Ellen Ingalla, Elizabeth Punnoose, Sophie Maïga, Franklin Peale, Deepak Sampath, Lisa D. Belmont, Wayne J. Fairbrother, Erwin R. Boghaert, Amy Young, Paul Tapang, Nguyen Tan, Walter C. Darbonne, Leslie Lee, Anatol Oleksijew, Joel D. Leverson, Michael J. Mitten, Jason Oeh, Martine Amiot, Peng Yue, Andrew J. Souers
Publikováno v:
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2016, ⟨10.1158/1535-7163.MCT-15-0730⟩
Molecular Cancer Therapeutics, 2016, ⟨10.1158/1535-7163.MCT-15-0730⟩
Molecular Cancer Therapeutics, American Association for Cancer Research, 2016, ⟨10.1158/1535-7163.MCT-15-0730⟩
Molecular Cancer Therapeutics, 2016, ⟨10.1158/1535-7163.MCT-15-0730⟩
BCL-2 family proteins dictate survival of human multiple myeloma cells, making them attractive drug targets. Indeed, multiple myeloma cells are sensitive to antagonists that selectively target prosurvival proteins such as BCL-2/BCL-XL (ABT-737 and AB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc0bb61cb377a0243be486b413d436b
https://www.hal.inserm.fr/inserm-01311318
https://www.hal.inserm.fr/inserm-01311318
Autor:
Olivier Chabre, Céline Duparc, Mathilde Sibony, Mari Suzuki, Philippe Touraine, Fideline Bonnet-Serrano, Estelle Louiset, Constantine A. Stratakis, Françoise Gobet, Jacques Young, Julie Le Mestre, Hervé Lefebvre, Jérôme Bertherat, Yves Reznik, Gérald Raverot
Publikováno v:
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2019, 104 (11), pp.4967-4980. ⟨10.1210/jc.2019-00425⟩
Journal of Clinical Endocrinology and Metabolism, 2019, 104 (11), pp.4967-4980. ⟨10.1210/jc.2019-00425⟩
J Clin Endocrinol Metab
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2019, 104 (11), pp.4967-4980. ⟨10.1210/jc.2019-00425⟩
Journal of Clinical Endocrinology and Metabolism, 2019, 104 (11), pp.4967-4980. ⟨10.1210/jc.2019-00425⟩
J Clin Endocrinol Metab
Context In the human adrenal, serotonin (5-HT), released by mast cells stimulates corticosteroid secretion through activation of type 4 serotonin receptors (5-HT4R). In primary pigmented nodular adrenocortical disease cells, activation of the cAMP/pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c805165afd6ae81f20b4f48b590f5f
https://hal-normandie-univ.archives-ouvertes.fr/hal-02419863
https://hal-normandie-univ.archives-ouvertes.fr/hal-02419863
Autor:
Cécile Aubert, Maithé Tauber, Ronan Roussel, Bénédicte Toussaint, François Pattou, Philippe Froguel, Jean-Michel Borys, Amjad Ghulam, Hélène Loiselle, Mathilde Boissel, Emmanuelle Durand, Sylvia Franc, Julie Kerr-Conte, Julie Maillet, Morgane Baron, Marlène Huyvaert, Amélie Bonnefond, Raphaël Boutry, J. Philippe, Jérémy Thomas, Guillaume Charpentier, Claire Lévy-Marchal, Michel Marre, Mehdi Derhourhi, Aurélie Dechaume, Emmanuel Vaillant, B. Balkau, Stefan Gaget, Raphael Scharfmann, Jacques Weill, Mickaël Canouil
Publikováno v:
Nature Medicine
Nature Medicine, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
Nature medicine
Nature Medicine, Nature Publishing Group, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
Nature Medicine, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
Nature medicine
Nature Medicine, Nature Publishing Group, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
International audience; The G-protein-coupled receptor accessory protein MRAP2 is implicated in energy control in rodents, notably via the melanocortin-4 receptor1. Although some MRAP2 mutations have been described in people with obesity1-3, their fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e4070864d7e526bb4fbf52762499c4
https://www.hal.inserm.fr/inserm-02439220/document
https://www.hal.inserm.fr/inserm-02439220/document
Autor:
Murielle Salomé, Jérôme Rose, Audrey Ridoux, Bernhard Hesse, Delphine Vantelon, Jean-Claude Pairon, Shamila Vibhushan, Florence Canoui-Poitrine, Erwan Paineau, Emmanuel Paul, Bernard Angeletti, Sophie Lanone, Marie-Laure Franco-Montoya, Christophe Delacourt, Arnaud Tiendrebeogo, Jorge Boczkowski
Publikováno v:
Nanotoxicology
Nanotoxicology, 2017, 11 (4), pp.484-495. ⟨10.1080/17435390.2017.1311381⟩
Nanotoxicology, Taylor & Francis, 2017, 11 (4), pp.484-495. ⟨10.1080/17435390.2017.1311381⟩
Nanotoxicology, 2017, 11 (4), pp.484-495. ⟨10.1080/17435390.2017.1311381⟩
Nanotoxicology, Taylor & Francis, 2017, 11 (4), pp.484-495. ⟨10.1080/17435390.2017.1311381⟩
International audience; Due to the growing commercial applications of manufactured nanoparticles (NPs), toxicological studies on NPs, especially during the critical window of development, are of major importance. The aim of the study was to assess th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f57d566f6528e43624eac521bc95a87
https://hal.science/hal-01765447
https://hal.science/hal-01765447
Autor:
Sophie Vandermeersch, Antoine Durrbach, Lola Lecru, Mélanie Ferreira, Christos Chatziantoniou, Bogdan Hermeziu, Katia Posseme, Hélène François, Myriam Dao, Charlotte Mussini, Sophie Ferlicot
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2019, 23 (11), pp.7279-7288. ⟨10.1111/jcmm.14570⟩
Journal of Cellular and Molecular Medicine, Wiley Open Access, 2019, 23 (11), pp.7279-7288. ⟨10.1111/jcmm.14570⟩
International audience; Chronic allograft dysfunction (CAD), defined as the replacement of functional renal tissue by extracellular matrix proteins, remains the first cause of graft loss. The aim of our study was to explore the potential role of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d744aeeb319ce67a3e71a9f9ae661b
https://hal.sorbonne-universite.fr/hal-02538112/file/jcmm.14570.pdf
https://hal.sorbonne-universite.fr/hal-02538112/file/jcmm.14570.pdf
Autor:
Jean-Sébastien Hoffmann, Marie Tosolini, Cindy da Costa de Jesus, Malik Lutzmann, Caroline Marty, Dana Hodroj, Candice Marchive, Marcel Méchali, Caroline Bret, William Vainchenker, Isabelle Plo, Luc Forichon, Florence Bernex, Sophie Queille
Publikováno v:
Cell Reports
Cell Reports, 2019, 28 (11), pp.2851-2865. ⟨10.1016/j.celrep.2019.07.095⟩
Cell Reports, Elsevier Inc, 2019, 28 (11), pp.2851-2865. ⟨10.1016/j.celrep.2019.07.095⟩
Cell Reports, Vol 28, Iss 11, Pp 2851-2865.e4 (2019)
Cell Reports, 2019, 28 (11), pp.2851-2865. ⟨10.1016/j.celrep.2019.07.095⟩
Cell Reports, Elsevier Inc, 2019, 28 (11), pp.2851-2865. ⟨10.1016/j.celrep.2019.07.095⟩
Cell Reports, Vol 28, Iss 11, Pp 2851-2865.e4 (2019)
Summary: Hematopoiesis is particularly sensitive to DNA damage. Myeloid tumor incidence increases in patients with DNA repair defects and after chemotherapy. It is not known why hematopoietic cells are highly vulnerable to DNA damage. Addressing this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366bfa15cc97041ac2ba3ff5538324ad
https://doi.org/10.1016/j.celrep.2019.07.095
https://doi.org/10.1016/j.celrep.2019.07.095
Autor:
Matthieu Hatt, Loïc Campion, Philippe Meingan, Stéphane Supiot, Christine Kandel-Aznar, Caroline Rousseau, Ludovic Ferrer, Stéphane Guerif, Dimitris Visvikis, M. Doré, François Paris, Catherine Cheze-Le-Rest, Gregory Delpon, Vincent Potiron
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2018, 9 (11), pp.10005-10015. ⟨10.18632/oncotarget.24234⟩
Oncotarget, 2018, 9 (11), pp.10005-10015. ⟨10.18632/oncotarget.24234⟩
Oncotarget, Impact journals, 2018, 9 (11), pp.10005-10015. ⟨10.18632/oncotarget.24234⟩
Oncotarget, 2018, 9 (11), pp.10005-10015. ⟨10.18632/oncotarget.24234⟩
International audience; Purpose: Hypoxia is a major factor in prostate cancer aggressiveness and radioresistance. Predicting which patients might be bad candidates for radiotherapy may help better personalize treatment decisions in intermediate-risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255f15f60958f4c847f097c87c36ce86
https://www.hal.inserm.fr/inserm-01823478
https://www.hal.inserm.fr/inserm-01823478