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Autor:
Laura Handgriff, Nina Nirschl, Leah T. Braun, Max Seidensticker, Roland Ladurner, Christian Adolf, Lisa Sturm, Martin Reincke, Daniel A. Heinrich, Martin Bidlingmaier, Jens Ricke
Publikováno v:
Hormone and Metabolic Research
Excess aldosterone is associated with the increased risk of cardio-/cerebrovascular events as well as metabolic comorbidities not only due to its hypertensive effect but also due to its proinflammatory action. Autonomous cortisol secretion (ACS) in t
Autor:
Jian Wang, Feng Li, Chunqing Zhang, Wei Zhang, Lifen Wang, Xiaoquan Huang, Shiyao Chen, Liyuan Ni, Mei Xiao, Siyu Jiang, Yuan Ji
Publikováno v:
Endoscopy. 52:727-735
Background Oxaliplatin, used as first-choice treatment for colorectal cancer (CRC), induces sinusoidal endothelial injury and portal hypertension. This study investigated the characteristics of oxaliplatin-induced portal hypertension and evaluated th
Autor:
Karina Braga Gomes, Cláudia N. Ferreira, Ana Lúcia Cândido, Fernando M. Reis, Mariana F Bizzi, Ana Luiza Lunardi Rocha, Flávia R. Oliveira, Marcelo Mamede
Publikováno v:
Hormone and Metabolic Research. 52:718-723
Polycystic ovary syndrome (PCOS) is a chronic dysfunction associated with obesity and metabolic disorders that can be ameliorated by treatment with metformin. Brown adipose tissue (BAT) has been recently identified in adult humans, and irisin is a my
Autor:
Rhys Morris, C. Heledd Roberts
Publikováno v:
Thrombosis and Haemostasis. 120:912-923
Intermittent pneumatic compression (IPC) is a widely used and recommended method to prevent deep vein thrombosis. While the haemodynamic effects of IPC are well understood, the objective of this systematic review was to analyse the evidence for addit
Autor:
Bernhard, Benedikt, Stickel, Felix
Publikováno v:
Zeitschrift für Gastroenterologie. 58:451-455
Relapses after therapy with direct-acting antiviral agents (DAA) in chronic hepatitis C virus (HCV) infections are rare due to high efficacy of interferon-free therapy regimens. The presence of resistance-associated substitutions (RAS) in proteins ta
Publikováno v:
Semin Reprod Med
Adenomyosis is a nonmalignant uterine disorder in which endometrial tissue exists within and grows into the myometrium. Animal models have generated limited insight into the still-unclear pathogenesis of adenomyosis, provided a platform for preclinic
Autor:
Werner Streif, Ralf Knöfler
Publikováno v:
Hämostaseologie. 40:226-232
The aim of this review is to provide practical guidance for the treatment of carriers of haemophilia and newborns presenting with haemophilia. Both mother and newborn have an increased risk for clinically relevant bleeding. An experienced team should
Autor:
Baiba Zvejniece, Maija Dambrova, Einars Kupats, J. Vrublevska, Gundega Stelfa, Liga Zvejniece, Edijs Vavers
Publikováno v:
Pharmacopsychiatry. 53:201-208
Phenibut is a nootropic drug that exerts anxiolytic and antinociceptive effects by acting on the GABAB receptor and the α2-δ subunit of voltage-dependent calcium channels. An increased number of reports of dependence to and intoxication by phenibut
Publikováno v:
Hormone and Metabolic Research. 52:588-597
Medullary Thyroid Carcinoma (MTC) is a rare neuroendocrine cancer that accounts for 1–2% of thyroid cancers in the United States (U.S.). While most cases are sporadic, 25% of MTC cases are hereditary. These hereditary cases occur in the setting of
Publikováno v:
Drug Research. 70:257-264
Aim Trigonelline is a potent phytochemical present in fenugreek, which has strong anti-oxidant and phytoestrogenic activities. This study was carried out to investigate this estrogenic activity as a possible mechanisms involved in preventing the symp