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Autor:
Cihan Ay, Stephan Nopp
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 146:944-949
Was ist neu? Häufigkeit thrombotischer Ereignisse COVID-19 ist deutlich mit einem erhöhten Thromboserisiko assoziiert. 5–11 % der PatientInnen auf Normalstationen und 18–28 % der intensivpflichtigen PatientInnen entwickeln eine venöse Thromboe
Autor:
Guillaume Lebreton, Ania Nieszkowska, Corinne Frere, Marc Pineton de Chambrun, Isabelle Martin-Toutain, Guillaume Hékimian, Manon Lejeune, Paul Masi, Juliette Chommeloux, Matthieu Schmidt, Charles-Edouard Luyt, Alain Combes, Nicolas Bréchot, Cyrielle Desnos, Pascal Leprince
Publikováno v:
Thrombosis and Haemostasis. 121:1031-1042
Hemostatic changes induced by extracorporeal membrane oxygenation (ECMO) support have been yet poorly documented in coronavirus-19 (COVID-19) patients who have a baseline complex hypercoagulable state. In this prospective monocentric study of patient
Publikováno v:
Hämostaseologie. 41:307-315
Hemorrhage after trauma remains a significant cause of preventable death. Trauma-induced coagulopathy (TIC) at the time of hospital admission is associated with an impaired outcome. Rather than a universal phenotype, TIC represents a complex hemostat
Autor:
Nathalie Enjolras, Yesim Dargaud, Sandra Le Quellec, Claude Negrier, Eloïse Perot, Jonathan Girard
Publikováno v:
Thrombosis and Haemostasis. 118:2053-2063
Prophylaxis is currently considered the optimal care for severe haemophilia. For patients and their families one of the major difficulties with prophylaxis is the need for frequent venipunctures. The half-life of standard factor IX (FIX) concentrates
Autor:
Elias Toubi, Zahava Vadasz
Publikováno v:
Seminars in Thrombosis and Hemostasis. 44:669-675
The involvement of the hemostatic system in immune-mediated inflammation is widely reported. Many coagulation factors play a role in the pathogenesis of autoimmune diseases, such as systemic vasculitis and systemic lupus erythematosus. Hemostatic dis
Autor:
Giulia Cervetti, Nadia Cecconi, Francesca Martini, Sara Galimberti, Mario Petrini, Aldo Paolicchi, Gabriele Buda
Publikováno v:
TH Open: Companion Journal to Thrombosis and Haemostasis
TH Open, Vol 03, Iss 01, Pp e64-e66 (2019)
TH Open, Vol 03, Iss 01, Pp e64-e66 (2019)
Abnormal coagulation properties indicative of a dysfibrinogenemia were found in the plasma of an asymptomatic 65-year-old male. An immunoglobulin k light chain was found to interfere with Fg functional assay and coagulation tests (activated partial t
Autor:
Jackie F. Price, Kristina F. Standeven, Mark W. J. Strachan, Katie A. Greenhalgh, Paul D. Baxter, Robert F. Storey, Robert A. S. Ariëns, Ramzi A. Ajjan, Peter J. Grant, S. H. Alzahrani
Publikováno v:
Greenhalgh, KA, Strachan, M W, Alzahrani, S H, Baxter, P D, Standeven, KF, Storey, R F, Ariens, R A S, Grant, P J, Price, J & Ajjan, R A 2017, ' BβArg448Lys polymorphism is associated with altered fibrin clot structure and fibrinolysis in type 2 diabetes ', Thrombosis and Haemostasis, vol. 117, no. 2, pp. 295-302 . https://doi.org/10.1160/TH16-07-0554
SummaryBoth type 2 diabetes (T2DM) and Bß448Lys variant of fibrinogen are associated with dense fibrin clots, impaired fibrinolysis and increased cardiovascular risk. It was our objective to investigate whether BßArg448Lys adds to vascular risk by
Autor:
Lars Björck, Matthias Mörgelin, Joost C. M. Meijers, Clément Naudin, Sinead M. Hurley, Erik Malmström, Heiko Herwald, Oonagh Shannon, Tom Plug
Publikováno v:
Thrombosis and haemostasis, 114(4), 717-726. Schattauer GmbH
SummaryActivation of thrombin is a critical determinant in many physiological and pathological processes including haemostasis and inflammation. Under physiological conditions many of these functions are involved in wound healing or eradication of an
Publikováno v:
Seminars in Thrombosis and Hemostasis. 40:621-633
The incidence of venous thromboembolism (VTE) is well recognized to increase with aging. Concurrently, the plasma concentrations of many coagulation factors (e.g., fibrinogen, factor [F] V, FVII, FVIII, and FIX) increase with aging, as does von Wille
Publikováno v:
Arzneimittelforschung. 54:705-710
Disseminated intravascular coagulation (DIC) is a pathological syndrome, which occurs following the uncontrolled widespread activation of blood coagulation, resulting in the intravascular formation of fibrin, which may lead to thrombotic occlusion of