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Autor:
Patrick Haider, Joseph Pultar, Johann Wojta, Svitlana Demyanets, Patricia P. Wadowski, Simon Panzer, Beate Eichelberger, Stefan Stojkovic, Silvia Lee, Constantin Weikert, Christian Hengstenberg, Thomas Gremmel
Publikováno v:
Thrombosis and Haemostasis. 121:913-922
Background Monocyte–platelet aggregates (MPAs) are a sensitive marker of in vivo platelet activation in acute coronary syndrome (ACS) and associated with clinical outcomes. MicroRNAs (miRs) play an important role in the regulation of platelet activ
Autor:
Keith Morris, D. Aled Rees, Philip E. James, Vitaliy Androshchuk, Nicholas Burnley-Hall, Richard Anderson, Fairoz Abdul, Nick Ossei-Gerning
Publikováno v:
Thrombosis and Haemostasis. 118:112-122
Extracellular vesicles (EVs) are implicated in the pathogenesis of cardiovascular disease (CVD). Specifically, platelet-derived EVs are highly pro-coagulant, promoting thrombin generation and fibrin clot formation. Nitrate supplementation exerts bene
Autor:
Peter Pickkers, P. G. De Groot, A.J.A.M. van der Ven, Rahajeng N. Tunjungputri, Esther Peters, Q. de Mast
Publikováno v:
Thrombosis and Haemostasis, 116, 1111-1121
Thrombosis and Haemostasis, 116, 6, pp. 1111-1121
Europe PubMed Central
Thrombosis and Haemostasis, 116, 6, pp. 1111-1121
Europe PubMed Central
Contains fulltext : 172714.pdf (Publisher’s version ) (Closed access) Sepsis-associated acute kidney injury (AKI) is associated with high morbidity and mortality. Excessive platelet activation contributes to AKI through the formation of microthromb
Autor:
Andrea Ceccacci, Laura Alemanno, R Guerriero, Massimo Mancone, Maria Luisa Guarino, Isabella Massimi, Luigi Frati, Dominick J. Angiolillo, Fabio M. Pulcinelli
Chronic treatment with aspirin in healthy volunteers (HVs) is associated with recovery of adenosine diphosphate (ADP)-induced platelet activation. The purinergic P2Y1 receptor exerts its effects via a Gq-protein, which is the same biochemical pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b72fa0ee73a4ef637f2a7c6a5cf5b17
http://hdl.handle.net/11573/1238243
http://hdl.handle.net/11573/1238243
Publikováno v:
Hormone and Metabolic Research. 49:5-9
Nowadays, GLP-1 receptor agonists are widely used as effective and safe antidiabetic medications. In addition to glucose-dependent insulin secretion, their effects reach beyond glucose control. Previously, it has been shown that acute administration
Publikováno v:
Drug Research. 66:345-350
The aim of this study is to investigate ipragliflozin as an initial type 2 diabetes (T2DM) drug.Ipragliflozin 25-50 mg/day monotherapy was performed with drug naïve subjects with T2DM (n=31). As a comparator, 12.5-25 mg/day alogliptin monotherapy wa
Publikováno v:
Pharmacopsychiatry. 48:215-218
Introduction: Inflammation-mediated changes in drug metabolism may increase drug levels in blood and lead to intoxications. The objective of this study was to find out whether elevated serum levels of C-reactive protein (CRP) are associated with incr
Autor:
Lucio C. Rovati, C. Benvenuti, Monique Zangarini, G. Giacovelli, Federica Sala, Stefano Persiani, Milena Colovic, Beatrice Barbetta, C. Manzotti, Cristina Vitalini, Y. Donazzolo
Publikováno v:
Drug Research. 66:136-140
Background: Post-menopausal women under treatment with levothyroxine for their medical conditions may take concomitantly dietary supplements containing soy isoflavones in combination to treat their post-menopausal symptoms. The aim of this study was
Publikováno v:
Pharmacopsychiatry. 49:76-78
In this article a case of carbamazepine overdose is reported. It is common to use immuno-based methods in the field of therapeutic drug monitoring but it might be difficult to adapt such values to toxicological cases. For carbamazepine overdoses it i
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 122:469-476
To compare the efficacy and safety of adding liraglutide, saxagliptin and vildagliptin to current therapy in Chinese type 2 diabetes subjects with poor glycemic control.A 24-week, randomized, open-label, parallel clinical trial was performed. A total