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Autor:
S R Abd El-Khalik, M A Elsebaey, Marwa Mohamed Atef, Sherif Abd-Al Fattah Saber, Yasser Mostafa Hafez, Alaa I. Amer
Publikováno v:
British Journal of Biomedical Science. 78:122-129
BACKGROUND Colorectal cancer is one of the most common cancers worldwide and a major cause of cancer-related death. Thus molecular biomarkers for colorectal cancer have been proposed. The role of long non-coding RNA EGFR-AS1 in colorectal cancer is s
Autor:
Hang Chen, Zhi-Bin Ke, Hai Cai, Yun-Zhi Lin, Qing-Shui Zheng, Ning Xu, Yong Wei, Xue-Yi Xue, Jun-Ming Zhu, Qi Huang
Publikováno v:
Pathology and Oncology Research
Objective: To develop and validate ubiquitination-related molecular subtypes and a novel prognostic index using ubiquitination-related genes (URGs) for patients with bladder cancer (BCa).Materials and Methods: We downloaded the clinical data and tran
Publikováno v:
Pathology and Oncology Research
Background: The preoperative systemic inflammation response index (SIRI), based on peripheral neutrophil (N), monocyte (M), and lymphocyte (L) counts, has shown mounting evidence as an effective prognostic indicator in some malignant tumors. The aim
Autor:
Rui Wang, Yingjie Liu, Wen Zhuang, Lie Yang, Yujie Zhang, Chao Fang, Jie Ping, Chun-Run Ling, Tao Xu, Lili Zhu, Jinglin Zhang, Mo-Jin Wang
Publikováno v:
Pathology and Oncology Research
Histological subtype plays an important role in the different clinical characteristics and survival outcomes of patients with colorectal carcinoma (CRC). However, in previous studies, the influences of tumor locations and tumor stages have not been s
Publikováno v:
Pathology and Oncology Research
Background: PD-L1 expression differs from 19 to 92% in various cancer subtypes. Its expression carries a worse prognostic value in various malignancies and could also be used as a predictive marker for immune checkpoint inhibitor response. This study
Autor:
João C. D. Muzzi, Jessica M. Magno, Milena A. Cardoso, Juliana de Moura, Mauro A. A. Castro, Bonald C. Figueiredo
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology, Vol 12 (2021)
Despite progress in understanding the biology of adrenocortical carcinoma (ACC), treatment options have not dramatically changed in the last three decades, nor have we learned how to avoid some of its long-term side effects. Our goal was to improve t
Circulating Survivin Protein Levels in Lung Cancer Patients Treated With Platinum-Based Chemotherapy
Autor:
Andras Bikov, Zsofia Lazar, Reka Nagy, Peter Horvath, Gabriella Gálffy, Gabriella Pinter, Laszlo Kunos, Rita Puskás
Publikováno v:
Pathology and Oncology Research
The survivin protein contributes to the development and progression of tumors. Protein expression and mRNA levels correlate with clinicopathological parameters and survival of cancer patients. Our purpose was to evaluate whether circulating survivin
Autor:
Zsolt Abonyi-Tóth, Krisztián Horváth, Balázs Nagy, László Urbán, Veronika Sárosi, Krisztina Bogos, Zoltán Polányi, Zoltán Kiss, Judit Moldvay, Zsófia Nagy-Erdei, Nóra Bittner, Lilla Tamási, Andrea Daniel, Gyula Ostoros, Aladár Vastag, György Rokszin, Veronika Müller, Gabriella Gálffy, Zoltán Vokó
Publikováno v:
Pathology and Oncology Research
Background: No assessment was conducted describing the age and gender specific epidemiology of lung cancer (LC) prior to 2018 in Hungary, thus the objective of this study was to appraise the detailed epidemiology of lung cancer (ICD-10 C34) in Hungar
Publikováno v:
Pathology and Oncology Research
Background: The objective was to explore the discordance in the expression of the estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki-67 between primary and recurrent/metastatic lesions in patie
Autor:
Roberto Sánchez-Reyes, Luis Cabrera-Miranda, Héctor Aquiles Maldonado-Martínez, Suraj Samtani-Bassarmal, Oscar Arrieta, Graciela Cruz-Rico, Luis Lara-Mejía, Xitlally Popa-Navarro, Rodrigo Catalán, Dennis López-Sánchez, Alejandro Avilés-Salas
Publikováno v:
Pathology and Oncology Research
Background: Programmed cell death-ligand 1 (PD-L1) protein expression is one of the most extensively studied biomarkers in patients with non-small cell lung cancer (NSCLC). However, there is scarce information regarding its association with distinct