Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yoonhee Kim"'
Autor:
Yoonhee Kim, Tae Hee Ko, Chunmei Jin, Yinhua Zhang, Hyae Rim Kang, Ruiying Ma, Huiling Li, Jong-Il Choi, Kihoon Han
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Shank3 is a member of the Shank family proteins (Shank1–3), which are abundantly present in the postsynaptic density (PSD) of neuronal excitatory synapses. As a core scaffold in the PSD, Shank3 plays a critical role in organizing the macromolecular
Externí odkaz:
https://doaj.org/article/4809dd1322b645638fa70cb197674b80
Autor:
Min-gu Kang, Jung-Yeon Choi, Hyun-Jung Yoo, Si-Young Park, Yoonhee Kim, Ji Yoon Kim, Sun-wook Kim, Cheol-Ho Kim, Kwang-il Kim
Publikováno v:
Frontiers in Nutrition, Vol 9 (2023)
BackgroundMalnutrition is prevalent among hospitalized older patients. Therefore, this study aimed to investigate the association between nutritional status [assessed using the Mini Nutritional Assessment (MNA) and serum albumin levels] and adverse o
Externí odkaz:
https://doaj.org/article/85db36c452c8442682f3c9e8cb2a961f
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Prion diseases are fatal infectious diseases caused by conformational changes of a prion protein (PrPSc) derived from a normal prion protein (PrPC). Prion diseases have been reported in several mammalian hosts but not in any birds, including the most
Externí odkaz:
https://doaj.org/article/2123c40e5f744ddd8060b935d814eda3
Autor:
Chunmei Jin, Hyojin Kang, Taesun Yoo, Jae Ryun Ryu, Ye-Eun Yoo, Ruiying Ma, Yinhua Zhang, Hyae Rim Kang, Yoonhee Kim, Hyunyoung Seong, Geul Bang, Sangwoo Park, Seok-Kyu Kwon, Woong Sun, Hyunkyung Kim, Jin Young Kim, Eunjoon Kim, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2021)
Variants of the SH3 and multiple ankyrin repeat domains 3 (SHANK3), which encodes postsynaptic scaffolds, are associated with brain disorders. The targeted alleles in a few Shank3 knock-out (KO) lines contain a neomycin resistance (Neo) cassette, whi
Externí odkaz:
https://doaj.org/article/3b0f76fae5d0442a8ae3a8d14537d7bc
Autor:
Yinhua Zhang, Rim Kang Hyae, Seung-Hyun Lee, Yoonhee Kim, Ruiying Ma, Chunmei Jin, Ji-Eun Lim, Seoyeon Kim, Yeju Kang, Hyojin Kang, Su Yeon Kim, Seok-Kyu Kwon, Se-Young Choi, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
The cytoplasmic fragile X mental retardation 1 (FMR1)-interacting protein 2 (CYFIP2) gene is associated with epilepsy, intellectual disability (ID), and developmental delay, suggesting its critical role in proper neuronal development and function. CY
Externí odkaz:
https://doaj.org/article/ac0c71e09bd841429a58affb1fdfb6bd
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Genetic variants of the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene, which encodes excitatory postsynaptic core scaffolds cause numerous brain disorders. Several lines of Shank3 knock-out (KO) mice with deletions of different Shank3 exons
Externí odkaz:
https://doaj.org/article/fce54f8dc26d4261b12bbd37e18edebd
Autor:
Yinhua Zhang, Hyojin Kang, Yeunkum Lee, Yoonhee Kim, Bokyoung Lee, Jin Yong Kim, Chunmei Jin, Shinhyun Kim, Hyun Kim, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2019)
Cytoplasmic FMR1-interacting protein 2 (CYFIP2) is a key component of the WAVE regulatory complex (WRC) which regulates actin polymerization and branching in diverse cellular compartments. Recent whole exome sequencing studies identified de novo hots
Externí odkaz:
https://doaj.org/article/0a43a6332f0b45c798b8d235b7e9bdc6
Autor:
Chunmei Jin, Hyojin Kang, Jae Ryun Ryu, Shinhyun Kim, Yinhua Zhang, Yeunkum Lee, Yoonhee Kim, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Variants of the SH3 and multiple ankyrin repeat domain 3 (SHANK3) gene, encoding excitatory postsynaptic core scaffolding proteins, are causally associated with numerous neurodevelopmental and neuropsychiatric disorders, including autism spectrum dis
Externí odkaz:
https://doaj.org/article/568ed34b70d44b399a655abedeea5f58
Autor:
Yeunkum Lee, Sun Gyun Kim, Bokyoung Lee, Yinhua Zhang, Yoonhee Kim, Shinhyun Kim, Eunjoon Kim, Hyojin Kang, Kihoon Han
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Mania causes symptoms of hyperactivity, impulsivity, elevated mood, reduced anxiety and decreased need for sleep, which suggests that the dysfunction of the striatum, a critical component of the brain motor and reward system, can be causally associat
Externí odkaz:
https://doaj.org/article/4e053be4199c424abb6fbcb1944be5a4
Autor:
Hyojin Kang, Bokyoung Lee, Won Ki Kim, Kihoon Han, Yeunkum Lee, Shinhyun Kim, Yoonhee Kim, Yinhua Zhang
Publikováno v:
Frontiers in Molecular Neuroscience
FRONTIERS IN MOLECULAR NEUROSCIENCE(10)
FRONTIERS IN MOLECULAR NEUROSCIENCE(10)
Recent molecular genetic studies have identified 100s of risk genes for various neurodevelopmental and neuropsychiatric disorders. As the number of risk genes increases, it is becoming clear that different mutations of a single gene could cause diffe