Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Michèle Ramsay"'
Autor:
Jean-Tristan Brandenburg, Wenlong Carl Chen, Palwende Romuald Boua, Melanie A. Govender, Godfred Agongo, Lisa K. Micklesfield, Hermann Sorgho, Stephen Tollman, Gershim Asiki, Felistas Mashinya, Scott Hazelhurst, Andrew P. Morris, June Fabian, Michèle Ramsay
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundGenome-wide association studies (GWAS) have predominantly focused on populations of European and Asian ancestry, limiting our understanding of genetic factors influencing kidney disease in Sub-Saharan African (SSA) populations. This study p
Externí odkaz:
https://doaj.org/article/4754b0bfc4da4c1b9ba3acd10e3491ca
Autor:
Cassandra C. Soo, Meagan T. Farrell, Stephen Tollman, Lisa Berkman, Almut Nebel, Michèle Ramsay
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/286cc16d662f4269bab6f65783b86292
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Globally, chronic kidney disease (CKD) contributes substantial morbidity and mortality. Recently, various ‘omics platforms have provided insight into the molecular basis of kidney dysfunction. This scoping review is a synthesis of the current liter
Externí odkaz:
https://doaj.org/article/44eb43e613d84c80b9b40413e59fda6a
Autor:
Cassandra C. Soo, Meagan T. Farrell, Stephen Tollman, Lisa Berkman, Almut Nebel, Michèle Ramsay
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Apolipoprotein E (APOE) 𝜀4 allele carrier status is well known for its association with an increased likelihood of developing Alzheimer’s disease, but its independent role in cognitive function is unclear. APOE genetic variation is understudied
Externí odkaz:
https://doaj.org/article/3427339be5764db1b081582b572e0bcb
Autor:
Siphiwe N. Dlamini, Ananyo Choudhury, Michèle Ramsay, Lisa K. Micklesfield, Shane A. Norris, Nigel J. Crowther, Andrew A. Crawford, Brian R. Walker, Zané Lombard, Julia H. Goedecke
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Research in European and Asian populations has reported associations between single nucleotide polymorphisms (SNPs) in CYP17A1 and SERPINA6/A1 and circulating glucocorticoid concentrations, and some key cardiometabolic risk factors. This study aimed
Externí odkaz:
https://doaj.org/article/e3a7eaac8ce24a07b52ebf6476835243
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Cancer is a critical health burden in Africa, and mortality rates are rising rapidly. Treatments are expensive and often cause adverse drug reactions (ADRs). Fluoropyrimidine treatments can lead to severe toxicity events which have been linked to var
Externí odkaz:
https://doaj.org/article/e4469a75634a451d877ab4b5331cadbf
Autor:
Godfred Agongo, Lucas Amenga-Etego, Engelbert A. Nonterah, Cornelius Debpuur, Ananyo Choudhury, Amy R. Bentley, Abraham R. Oduro, Charles N. Rotimi, Nigel J. Crowther, Michèle Ramsay, AWI-Gen and H3Africa, H3Africa
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Variations in lipid levels are attributed partly to genetic factors. Genome-wide association studies (GWASs) mainly performed in European, African American and Asian cohorts have identified variants associated with LDL-C, HDL-C, total cholesterol (TC
Externí odkaz:
https://doaj.org/article/dda133a5d5904473a385ed6212011d05
Autor:
Palwende Romuald Boua, Jean-Tristan Brandenburg, Ananyo Choudhury, Scott Hazelhurst, Dhriti Sengupta, Godfred Agongo, Engelbert A. Nonterah, Abraham R. Oduro, Halidou Tinto, Christopher G. Mathew, Hermann Sorgho, Michèle Ramsay
Publikováno v:
Frontiers in Genetics, Vol 10 (2020)
IntroductionAtherosclerosis is a key contributor to the burden of cardiovascular diseases (CVDs) and many epidemiological studies have reported on the effect of smoking on carotid intima-media thickness (cIMT) and its subsequent effect on CVD risk. G
Externí odkaz:
https://doaj.org/article/c87b7b4664f347d5ae36ba46733cf02d
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 6 (2015)
Frontiers in Genetics, Vol 6 (2015)
Fetal alcohol syndrome (FAS) is a devastating developmental disorder resulting from alcohol exposure during fetal development. It is a considerable public health problem worldwide and is characterized by central nervous system abnormalities, dysmorph
Autor:
Michèle Ramsay, Jaysen Knezovich
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
Frontiers in Genetics
Frontiers in Genetics
Imprinted loci play a critical role in fetal development. Their expression is often regulated by CCCTC-binding factor (CTCF) protein binding at imprinting control regions (ICRs). Prenatal alcohol exposure has been shown to reduce global DNA methylati