Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lishomwa C. Ndhlovu"'
Autor:
Erika G. Marques de Menezes, Scott A. Bowler, Cecilia M. Shikuma, Lishomwa C. Ndhlovu, Philip J. Norris
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundAlthough effective antiretroviral therapy (ART) has improved the life expectancy of people with HIV (PWH), the prevalence of milder forms of HIV-associated neurocognitive disorders (HAND) persist, and it is associated with systemic and neur
Externí odkaz:
https://doaj.org/article/6de4734169194ec2ae940746b4ace112
Autor:
Benderli Christine Nana, Livo Forgu Esemu, Michael Ebangha Besong, Derrick Hyacinthe Nyasse Atchombat, Kazuhiro Ogai, Thérèse M. Patricia Sobgui, Chris Marco Mbianda Nana, Reine Medouen Ndeumou Seumko’o, Honoré Awanakan, Gabriel Loni Ekali, Rose Gana Fomban Leke, Shigefumi Okamoto, Lishomwa C. Ndhlovu, Rosette Megnekou
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundHuman Herpesvirus-8 (HHV-8) is the etiologic agent of Kaposi’s sarcoma (KS), a multicentric angio-proliferative cancer commonly associated with Human Immunodeficiency Virus (HIV) infection. KS pathogenesis is a multifactorial condition hi
Externí odkaz:
https://doaj.org/article/b4416675fe41442483012332fa4872d0
Autor:
Erika G. Marques de Menezes, Jocelyn S. Liu, Scott A. Bowler, Leila B. Giron, Michelle L. D’Antoni, Cecilia M. Shikuma, Mohamed Abdel-Mohsen, Lishomwa C. Ndhlovu, Philip J. Norris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundNeurocognitive impairment remains prevalent in people with HIV (PWH) despite long term virological suppression by antiretroviral therapy (ART) regimens. Systemic and neuro-inflammatory processes are suggested to contribute to the complex pa
Externí odkaz:
https://doaj.org/article/536e2f5815834ab88349d615c6ec14ca
Autor:
Stephen T. Yeung, Thomas A. Premeaux, Li Du, Toshiro Niki, Satish K. Pillai, Kamal M. Khanna, Lishomwa C. Ndhlovu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
SARS-CoV-2 remains a global health crisis even with effective vaccines and the availability of FDA approved therapies. Efforts to understand the complex disease pathology and develop effective strategies to limit mortality and morbidity are needed. R
Externí odkaz:
https://doaj.org/article/0d69024d80a345bfa03b99c5c3ccbc67
Autor:
Alina P. S. Pang, Albert T. Higgins-Chen, Florence Comite, Ioana Raica, Christopher Arboleda, Hannah Went, Tavis Mendez, Michael Schotsaert, Varun Dwaraka, Ryan Smith, Morgan E. Levine, Lishomwa C. Ndhlovu, Michael J. Corley
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence suggest that severe COVID-19 is associated with durable scars to the epigenome. Specifically, aberrant DNA methylation changes in immune cells and alterations to
Externí odkaz:
https://doaj.org/article/b77f973272304187808a89b6508d8ed7
Autor:
Thomas A. Premeaux, Stephen T. Yeung, Zaheer Bukhari, Scott Bowler, Oral Alpan, Raavi Gupta, Lishomwa C. Ndhlovu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a significant global health emergency with new variants in some cases evading current therapies and approved vaccines. COVID-19 pr
Externí odkaz:
https://doaj.org/article/05b28cfe031e491a84bb5f026c68ac59
Autor:
Danielle M. Clements, Brenndan Crumley, Glen M. Chew, Elijah Davis, Roberta Bruhn, Edward L. Murphy, Lishomwa C. Ndhlovu, Pooja Jain
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) develops in 1–5% of HTLV-1-infected individuals. Previous studies by us and others have shown that the expression of negative immune checkp
Externí odkaz:
https://doaj.org/article/fc7b85aac1ec4ddcac0656dff6dac38c
Autor:
Robert H. Paul, Cecilia M. Shikuma, Nguyen Van Vinh Chau, Lishomwa C. Ndhlovu, Nguyen Tat Thanh, Andrew C. Belden, Dominic C. Chow, Glen M. Chew, Thomas A. Premeaux, Vo Trieu Ly, Joseph A. D. McBride, Jacob D. Bolzenius, Thuy Le
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Long-term neurocognitive outcomes following first-line suppressive anti-retroviral therapy (ART) remain uncertain for individuals with HIV and hepatitis C (HCV) co-infection. The study examined neurocognitive performance before and after
Externí odkaz:
https://doaj.org/article/72b63a1d77724ca5a274f4c58fddb45b
Autor:
Thomas A. Premeaux, Shireen Javandel, Kalei R. J. Hosaka, Meredith Greene, Nicholas Therrien, Isabel E. Allen, Michael J. Corley, Victor G. Valcour, Lishomwa C. Ndhlovu
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The prevalence of age-related comorbidities is increased in people living with HIV, even in those well-controlled on combination antiretroviral therapy (ART). Persistent immune activation and inflammation may play pivotal roles in the pathogenesis; h
Externí odkaz:
https://doaj.org/article/528e876302d343b1bac79c110c2ec245
Autor:
Michelle L. D'Antoni, Kalpana J. Kallianpur, Thomas A. Premeaux, Michael J. Corley, Tsuyoshi Fujita, Elizabeth I. Laws, Debra Ogata-Arakaki, Dominic C. Chow, Vedbar S. Khadka, Cecilia M. Shikuma, Lishomwa C. Ndhlovu
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cognitive dysfunction persists in 30–50% of chronically HIV-infected individuals despite combination antiretroviral therapy (ART). Although monocytes are implicated in poor cognitive performance, distinct biological mechanisms associated with cogni
Externí odkaz:
https://doaj.org/article/5196fd22d21e4ee99e9a3809d87f1b51