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pro vyhledávání: '"11"'
Autor:
Astri Frafjord, Linn Buer, Clara Hammarström, Henrik Aamodt, Per Reidar Woldbæk, Odd Terje Brustugun, Åslaug Helland, Inger Øynebråten, Alexandre Corthay
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Tumor-specific T helper (Th) cells have a central role in the immune response against cancer. However, there exist distinct Th cell subsets with very different and antagonizing properties. Some Th subsets such as Th1 protect against cancer, while oth
Autor:
Loukas Chatzis, Andreas V. Goules, Ioanna E. Stergiou, Michael Voulgarelis, Athanasios G. Tzioufas, Efstathia K. Kapsogeorgou
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Recent studies suggest that elevated CXCL13 serum levels in patients with primary Sjögren’s syndrome (pSS) associate with minor salivary gland (MSG) histologic features, disease severity, as well as high-risk status for non-Hodgkin lymphoma (NHL)
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Elucidating the mechanisms contributing to the dysregulated host response to infection as part of the syndrome is a current challenge in sepsis research. Peripheral blood mononuclear cells are widely used in immunological studies. Density gradient ce
Autor:
Giovanni Antonelli, Daniela Pace, Stefano Spiezia, Sara Garberoglio, Umberto Brancaccio, DAmbrosio Edoardo, Maria Esposito, Claudia Misso, Chiara Offi
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2021)
Frontiers in Endocrinology, Vol 11 (2021)
Induced radiofrequency thermal ablation is the cytoreductive treatment of symptomatic benign thyroid nodules, metastatic and recurrent thyroid tumors and papillary thyroid microcarcinomas. It is a safe and effective alternative to surgery and it allo
Autor:
Lai Jiang, Bo Xu, Dun-Feng Xu, Wenbin Guan, Xiaoyan Zhu, Yuan Gao, Feng Li, Yan-Fei Mao, Rongrong Ren
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2021)
Frontiers in Endocrinology, Vol 11 (2021)
BackgroundThe majority of the critically ill patients may have critical illness-related corticosteroid insufficiency (CIRCI). The therapeutic effect of dexamethasone may be related to its ability to improve cortical function. Recent study showed that
Autor:
Valentina Cirello, Carla Colombo, Olga Karapanou, Gabriele Pogliaghi, Luca Persani, Laura Fugazzola
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
Several low penetration susceptibility risk loci or genes have been proposed in recent years with a possible causative role for familial non-medullary thyroid cancer (FNMTC), though the results are still not conclusive or reliable. Among all the cand
Autor:
Federica Costa, Rosanna Vescovini, Valentina Marchica, Paola Storti, Laura Notarfranchi, Benedetta Dalla Palma, Denise Toscani, Jessica Burroughs-Garcia, Maria Teresa Catarozzo, Gabriella Sammarelli, Nicola Giuliani
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology
Frontiers in Immunology
BackgroundThe PD-1/PD-L1 axis has recently emerged as an immune checkpoint that controls antitumor immune responses also in hematological malignancies. However, the use of anti-PD-L1/PD-1 antibodies in multiple myeloma (MM) patients still remains deb
Autor:
Jing Huang, Lynne-Marie Postovit, Eun Young Kang, Gabrielle M. Siegers, Martin Köbel, Indrani Dutta
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Gamma delta (γδ) T cells kill transformed cells, and increased circulating γδ T cells levels correlate with improved outcome in cancer patients; however, their function within the breast tumor microenvironment (TME) remains controversial. As tumo
Autor:
Mariana C. Costa, Camilla S. Paixão, Débora L. Viana, Bruno de O. Rocha, Maíra Saldanha, Lícia M. H. da Mota, Paulo R. L. Machado, Carla Pagliari, Maria de Fátima de Oliveira, Sergio Arruda, Edgar M. Carvalho, Lucas P. Carvalho
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Psoriasis is a chronic, inflammatory disease affecting the skin and joints. The pathogenesis of this disease is associated with genetic, environmental and immunological factors, especially unbalanced T cell activation and improper keratinocyte differ
Autor:
Maria Aliseychik, Anton Patrikeev, Fedor Gusev, Anastasia Grigorenko, Tatiana Andreeva, Arya Biragyn, Evgeny Rogaev
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
The immune system contributes to neurodegenerative pathologies. However, the roles of γδ T cells in Alzheimer's disease (AD) are poorly understood. Here, we evaluated somatic variability of T-cell receptor γ genes (TRGs) in patients with AD. We pe