Zobrazeno 1 - 10
of 10
pro vyhledávání: '"GUIXIANG XU"'
Autor:
Vaishnavi S. Jadhav, Lin, Peter B. C., Pennington, Taylor, Prisco, Gonzalo Viana Di, Jannu, Asha Jacob, Guixiang Xu, Moutinho, Miguel, Zhang, Jie, Atwood, Brady K., Puntambekar, Shweta S., Bissel, Stephanie J., Oblak, Adrian L., Landreth, Gary E., Lamb, Bruce T.
Additional file 9 : Table S7. Downregulated genes associated with oligodendrocyte/myelin in Trem2Y38C/Y38C versus WT mice. logFC = Log fold change.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76864957a553eaff33d3cc3dd071580b
Autor:
Vaishnavi S. Jadhav, Lin, Peter B. C., Pennington, Taylor, Prisco, Gonzalo Viana Di, Jannu, Asha Jacob, Guixiang Xu, Moutinho, Miguel, Zhang, Jie, Atwood, Brady K., Puntambekar, Shweta S., Bissel, Stephanie J., Oblak, Adrian L., Landreth, Gary E., Lamb, Bruce T.
Additional file 2 : Table S2. Primers for Sanger’s sequencing of predicted off-target mutations from CRISPR/Cas9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05999400d0a8ba365e9267179f8386bf
Autor:
Vaishnavi S. Jadhav, Lin, Peter B. C., Pennington, Taylor, Prisco, Gonzalo Viana Di, Jannu, Asha Jacob, Guixiang Xu, Moutinho, Miguel, Zhang, Jie, Atwood, Brady K., Puntambekar, Shweta S., Bissel, Stephanie J., Oblak, Adrian L., Landreth, Gary E., Lamb, Bruce T.
Additional file 10: Table S8. Downregulated genes associated with oligodendrocyte/myelin genes Trem2-/- versus WT mice. logFC = Log fold change.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05922db7031d2e508d1c5b8070de09fa
Autor:
Vaishnavi S. Jadhav, Lin, Peter B. C., Pennington, Taylor, Prisco, Gonzalo Viana Di, Jannu, Asha Jacob, Guixiang Xu, Moutinho, Miguel, Zhang, Jie, Atwood, Brady K., Puntambekar, Shweta S., Bissel, Stephanie J., Oblak, Adrian L., Landreth, Gary E., Lamb, Bruce T.
Additional file 1: Table S1. Primers for amplification of genomic regions predicted to have off-target mutations from CRISPR/Cas9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccfbb22f7cd10f5c81b3eb98d062d61
Autor:
Bemiller, Shane, Maphis, Nicole, Formica, Shane, Wilson, Gina, Miller, Crystal, Guixiang Xu, Kokiko-Cochran, Olga, Ki-Wook Kim, Jung, Steffen, Cannon, Judy, Crish, Samuel, Cardona, Astrid, Lamb, Bruce, Bhaskar, Kiran
Figure S1. Altered expression of Cx3cl1 and Cx3cr1 and protein levels of CX3CL1 in non-transgenic, Cx3cl1105Δ and. Cx3cl1−/− mice. Quantitative real-time PCR analysis showing the expression of Cx3cl1 and Cx3cr1 mRNAs (A and C), as well as ELISA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cfbac0f4826be2fea4e878adff623f
Autor:
Bemiller, Shane, McCray, Tyler, Allan, Kevin, Formica, Shane, Guixiang Xu, Wilson, Gina, Kokiko-Cochran, Olga, Crish, Samuel, Lasagna-Reeves, Cristian, Ransohoff, Richard, Landreth, Gary, Lamb, Bruce
Quantitative RT-PCR and Cytokine multiplex analysis of 6-month hTau and hTau;Trem2 −/− mice. A Whole-brain lysates from 6-month hTau (Trem2 +/+ ) and hTau;Trem2 −/− mice (n = 5–6 per group) were prepared for analysis using qRT-PCR with prim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf93d1e1c91584fb130195dc97511f86
Autor:
Bemiller, Shane, McCray, Tyler, Allan, Kevin, Formica, Shane, Guixiang Xu, Wilson, Gina, Kokiko-Cochran, Olga, Crish, Samuel, Lasagna-Reeves, Cristian, Ransohoff, Richard, Landreth, Gary, Lamb, Bruce
Quantification strategy for p-tau + neurons. A Cresyl violet staining was utilized to determine specific laminar layers II-III and IV-VI which were used to define quantitation of p-Tau+ neurons. A total of 2- medial sections were analyzed per mouse (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589b79fea0c95064a55d25b3913cae98
Autor:
Bemiller, Shane, McCray, Tyler, Allan, Kevin, Formica, Shane, Guixiang Xu, Wilson, Gina, Kokiko-Cochran, Olga, Crish, Samuel, Lasagna-Reeves, Cristian, Ransohoff, Richard, Landreth, Gary, Lamb, Bruce
A,B Western blot analysis reveals no alterations in cortical or hippocampal signaling molecules between 6-month non-transgenic BL6 control mice and Trem2 −/− mice. Additionally, no significant alterations in p-tau (C) were detected between BL6 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d987c02a18f995f65d08cc1a6bb675
Autor:
Bemiller, Shane, McCray, Tyler, Allan, Kevin, Formica, Shane, Guixiang Xu, Wilson, Gina, Kokiko-Cochran, Olga, Crish, Samuel, Lasagna-Reeves, Cristian, Ransohoff, Richard, Landreth, Gary, Lamb, Bruce
Increased tau pathology in 6-month hTau;Trem2−/− mice. A Western blot shows increased conformation specific anti-tau antibody MC1 reactivity in hTau;Trem2 −/− compared to hTau controls. B Increased ratio of Iba1 reactivity to AT8 Tau reactivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401ac884b1dba53383299e3bf907625b
Autor:
Bemiller, Shane, McCray, Tyler, Allan, Kevin, Formica, Shane, Guixiang Xu, Wilson, Gina, Kokiko-Cochran, Olga, Crish, Samuel, Lasagna-Reeves, Cristian, Ransohoff, Richard, Landreth, Gary, Lamb, Bruce
MAPK signaling changes detected in 3- month hTau;Trem2 −/− hippocampi despite no differences in tau pathology. Western blot analysis and quantification of hippocampal protein extracts from 3-month hTau (Trem2 +/+ ) and hTau;Trem2 −/− mice (n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42997a177655287a277d51922e4b675