Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eggan, Kevin"'
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Figure S5. External eye quantification scale for (GR)36 animals. For quantification of the enhancement effects of increased expression of HSF in the eye, (GR)36 animals received a score between 0 (normal eye) and 11 (extreme toxicity causing lethalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371a497118114a1bbf672a0d56bbb29f
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Figure S1. Bioinformatic method comparison for gene expression analysis of C9ORF72-associated ALS and sporadic ALS (sALS) in the frontal cortex and cerebellum. (a-d) Gene density plots comparing the expression levels of differentially expressed trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f47758d9a6a70391ad2e7f6945aafa9
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Figure S2. Gene networks in C9ORF72-ALS and sporadic ALS. (a) Protein-protein interaction network derived from differentially expressed transcripts in C9ORF72-ALS cerebellum. Those transcripts that are differentially expressed in both the frontal cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914367356cdb6157a9ed51ade395368e
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Figure S4. poly-GR expression results in the upregulation of heat shock response genes and dHSF1 in the adult fly nervous system. UAS-(GR)36 was expressed in the adult fly nervous system using the drug-inducible Gal4 driver, elavGS, for 16d. qPCR ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6951fe794268aa59456b5e620ad9014
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Table S4. Values from qPCR analysis in brain samples. (PDF 178 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e0f5ccc6358fb9265d38cfac1ad543a
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Figure S3. Activation of HSF1 in C9ORF72-ALS, FTLD, and combined ALS/FTLD patients. (a) Quantitative real-time PCR (qRT-PCR) for HSF1 target genes in the cerebellum of sporadic and C9ORF72-associated disease (n = 56 C9ORF72-ALS/FTLD, n = 42 sporadic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31ef7232160bace67019511de8a3d4ae
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Figure S3. Activation of HSF1 in C9ORF72-ALS, FTLD, and combined ALS/FTLD patients. (a) Quantitative real-time PCR (qRT-PCR) for HSF1 target genes in the cerebellum of sporadic and C9ORF72-associated disease (n = 56 C9ORF72-ALS/FTLD, n = 42 sporadic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30ac12106c72df30ea6bb0a00c42357f
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Table S1. Characteristics of patient cohort for brain samples used in qPCR analysis. (PDF 154 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5afbf604e37b67b4eda99bdeb44a209
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Table S2. Primer sequences for PCR. (PDF 167 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e9714028460d2a4da7648071e4e62f0
Autor:
Mordes, Daniel, Prudencio, Mercedes, Goodman, Lindsey, Klim, Joseph, Moccia, Rob, Limone, Francesco, Pietilainen, Olli, Kaitavjeet Chowdhary, Dickson, Dennis, Rademakers, Rosa, Bonini, Nancy, Petrucelli, Leonard, Eggan, Kevin
Table S1. Characteristics of patient cohort for brain samples used in qPCR analysis. (PDF 154 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22b32eff8dda585690448447903e5c3f