Zobrazeno 1 - 10
of 21
pro vyhledávání: '"11"'
Autor:
Nazanin Zounemat Kermani, Olivia R. Carroll, Jemma R. Mayall, Brian G. Oliver, Hock L. Tay, Gang Liu, Paul S. Foster, Elizabeth G. Holliday, Dikaia Xenaki, Sharon Mumby, Jay C. Horvat, R. Karim, Daniel M. Johnstone, Prabuddha S. Pathinayake, Debbie Trinder, Elizabeth A. Milward, Malcolm R. Starkey, Yike Guo, Kristy L. Martin, James W. Pinkerton, Jessica Weaver, Peter A. B. Wark, Philip M. Hansbro, Yusef Badi, Richard Kim, Ritambhara Aryal, Stelios Pavlidis, Khadem Ali, Ian M. Adcock, Amber L. Pillar, Alexandra C. Brown, Chantal Donovan
Publikováno v:
European Respiratory Journal. 55:1901340
Accumulating evidence highlights links between iron regulation and respiratory disease. Here, we assessed the relationship between iron levels and regulatory responses in clinical and experimental asthma.We show that cell-free iron levels are reduced
Autor:
Gallacher, David, Mitchell, Emma, Alber, Dagmar, Wach, Richard, Klein, Nigel, Marchesi, Julian R., Kotecha, Sailesh, Department of Child Health, School of Medicine, Cardiff University, Cardiff, UK, Institute of Child Health, University College London, London, UK, Neonatal Unit, North Bristol NHS Trust, Bristol, UK, School of Biosciences, Cardiff University, Cardiff, UK, Division of Integrative Systems Medicine and Digestive Disease, Imperial College London, London, UK
Publikováno v:
European Respiratory Journal. 55:1901909
BackgroundChronic lung disease of prematurity (CLD), also called bronchopulmonary dysplasia, is a major consequence of preterm birth, but the role of the microbiome in its development remains unclear. Therefore, we assessed the progression of the bac
Autor:
Sanjay Sethi, Alvar Agusti, Roger Paredes, Gary B. Huffnagle, Vicente Pérez Brocal, James D. Chalmers, Eric Bernasconi, Philip L. Molyneaux, Julia Ponomarenko, Chaysavanh Manichanh, Eduard Monsó, Oriol Sibila, Jordi Dorca, Rosa Faner
Publikováno v:
European Respiratory Journal. 49:1602086
The healthy lung has previously been considered to be a sterile organ because standard microbiological culture techniques consistently yield negative results. However, culture-independent techniques report that large numbers of microorganisms coexist
Autor:
M Camps Serra, A. Torres, Tomás Pumarola, Rafael Perelló, Carlos Cervera, A. Moreno, M. T. Jimenez de Anta, M.A. Marcos
Publikováno v:
European Respiratory Journal. 31:618-624
Community-acquired pneumonia (CAP) is a serious lower respiratory tract infection associated with significant morbidity and mortality in immunocompromised patients. The present study evaluated the clinical spectrum of CAP in immunocompromised hosts a
Publikováno v:
European Respiratory Journal. 25:482-489
As a defective anti-polysaccharide response can exist in the absence of an immunoglobulin deficiency, a series of 26 patients with bronchiectasis of unknown aetiology was vaccinated with a 23-valent pneumococcal polysaccharide vaccine. All patients s
Autor:
Tina Heyder, Emil Wiklundh, Anders Eklund, Anna James, Sven-Erik Dahlén, Johan Grunewald, Roman A. Zubarev, Susanna L. Lundström
Publikováno v:
ERJ Open Research. 4:00033-2018
Characterising chronic lung diseases is challenging. New, less invasive diagnostics are needed to decipher disease pathologies and subphenotypes. Fc galactosylation is known to affect IgG function, and is altered in autoimmune disorders and under oth
Autor:
Phillip Monk, Rachel Pestridge, Jonathan Macintyre, James Roberts, Ajerico del Rosario, Chang Xiao, Sebastian L. Johnston, Rona Beegan, Peter Adura, Tatiana Kebadze, Eleanor Reed, Christine B. Boxall, James E. Gern, Victoria Cornelius, Ratko Djukanovic, Juliya Aniscenko
Publikováno v:
European Respiratory Journal
To the Editor : The majority of asthma exacerbations are associated with respiratory virus infections, mostly rhinoviruses (RVs) [1], due to enhanced inflammation in the airways [2]. These occur despite symptom control with inhaled corticosteroids (I
Publikováno v:
European Respiratory Journal. 26:265-270
Effector memory T-cells (CD45RO+) may provide pro-inflammatory signals that contribute to the persistent airway inflammation that is characteristic of asthma, and reduced apoptosis of these cells may prolong their effects. The present authors compare
Publikováno v:
European Respiratory Journal. 24:609-614
Exhaled nitric oxide (eNO) concentration measurement may permit the noninvasive estimation of the severity of airways inflammation in respiratory tract diseases. The aim of this study was to evaluate the correlation between eNO concentration and the
Autor:
J. M. M. Van Den Bosch, Jan Willem J. Lammers, K. A. Boomars, Leo Koenderman, René C. Schweizer, Pieter Zanen
Publikováno v:
European Respiratory Journal. 11:1009-1014
Increased numbers of eosinophils have been found in bronchoalveolar lavage (BAL) fluid obtained from patients with idiopathic pulmonary fibrosis (IPF). This suggests the presence of one or more cytokines in the lung tissue of patients with IPF, which