Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Lorcan McGarvey"'
Autor:
Lorcan McGarvey, Alyn H. Morice, Ashley Martin, Vicky W. Li, Michael J. Doane, Eduardo Urdaneta, Jonathan Schelfhout, Helen Ding, Eileen Fonseca
Publikováno v:
ERJ Open Research, Vol 9, Iss 4 (2023)
Background Chronic cough, defined as daily cough for at least 8 weeks, negatively affects quality of life and work productivity and increases healthcare resource utilisation. We aimed to determine the prevalence and burden of chronic cough in the UK.
Externí odkaz:
https://doaj.org/article/fac920275fc44d278d6bc90a4cbcfd6a
Autor:
Elena Kum, Gordon H. Guyatt, Caroline Munoz, Suzanne Beaudin, Shelly-Anne Li, Rayid Abdulqawi, Huda Badri, Louis-Philippe Boulet, Ruchong Chen, Peter Dicpinigaitis, Lieven Dupont, Stephen K. Field, Cynthia L. French, Peter G. Gibson, Richard S. Irwin, Paul Marsden, Lorcan McGarvey, Jaclyn A. Smith, Woo-Jung Song, Paul M. O'Byrne, Imran Satia
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Background Cough symptom severity represents an important subjective end-point to assess the impact of therapies for patients with refractory or unexplained chronic cough (RCC/UCC). As existing instruments assessing the severity of cough are neither
Externí odkaz:
https://doaj.org/article/151080ea31be480ea6c85ee1880825c7
Publikováno v:
European Respiratory Review, Vol 30, Iss 162 (2021)
Chronic cough is defined in adults as a cough that lasts for ≥8 weeks. When it proves intractable to standard-of-care treatment, it can be referred to as refractory chronic cough (RCC). Chronic cough is now understood to be a condition of neural dy
Externí odkaz:
https://doaj.org/article/c4a1e2e2a26740839b31eabe28c33b86
Autor:
Valerie J. Ludbrook, Kate E. Hanrott, James L. Kreindler, Joanna E. Marks-Konczalik, Nick P. Bird, Debbie A. Hewens, Misba Beerahee, David J. Behm, Alyn Morice, Lorcan McGarvey, Sean M. Parker, Surinder S. Birring, Jaclyn Smith
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Objective Airway sensory nerves involved in the cough reflex are activated by adenosine triphosphate (ATP) agonism of P2X purinoceptor 3 (P2X3) receptors. Transient receptor potential vanilloid 4 (TRPV4) channel activation causes ATP release from air
Externí odkaz:
https://doaj.org/article/8898a21c0e9847d39d530aa3f6cd63d4
Autor:
David R. Muccino, Alyn H. Morice, Surinder S. Birring, Peter V. Dicpinigaitis, Ian D. Pavord, Christopher Assaid, Huub Jan Kleijn, Azher Hussain, Carmen La Rosa, Lorcan McGarvey, Jaclyn A. Smith
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
Background We present study designs, dose selection and preliminary patient characteristics from two phase 3 clinical trials of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough (RCC) or unexplained chronic cough (UCC). Methods COUG
Externí odkaz:
https://doaj.org/article/797aecd766a64455a4cd9c812cd2c339
Autor:
Louise Dunn, Kirsty Honeyford, Liam G Heaney, Claire A. Butler, Yuqing Zhang, R Jayne Logan, P Jane McDowell, John H. Stone, Lorcan McGarvey
Publikováno v:
The European Respiratory Journal
article-version (VoR) Version of Record
McDowell, P J, Stone, J H, Zhang, Y, Honeyford, K, Dunn, L, Logan, R J, McGarvey, L P A, Butler, C A & Heaney, L G 2022, ' Glucocorticoid toxicity reduction with Mepolizumab using the glucocorticoid toxicity index ', European Respiratory Journal, vol. 59, no. 1 . https://doi.org/10.1183/13993003.00160-2021
article-version (VoR) Version of Record
McDowell, P J, Stone, J H, Zhang, Y, Honeyford, K, Dunn, L, Logan, R J, McGarvey, L P A, Butler, C A & Heaney, L G 2022, ' Glucocorticoid toxicity reduction with Mepolizumab using the glucocorticoid toxicity index ', European Respiratory Journal, vol. 59, no. 1 . https://doi.org/10.1183/13993003.00160-2021
Background Reduction in glucocorticoid exposure is the primary benefit of new biologic treatments in severe asthma, but there is currently no evidence that reduction in glucocorticoid exposure corresponds to a proportionate reduction in associated to
Autor:
Surinder S. Birring, Lorcan McGarvey, David Muccino, Jaclyn A. Smith, Allison Martin Nguyen, Qing Li, Peter V. Dicpinigaitis, A. Tzontcheva, Carmen La Rosa, Jonathan Schelfhout, Alyn H. Morice, Ian D. Pavord
Publikováno v:
Monitoring airway disease.
Autor:
Adel H. Mansur, Timothy J. Powell, Peter Bradding, Anna Hayman, Stephen J. Fowler, Catherine Borg, Simon Couillard, Sarah Poole, Angela Moran, Lorcan McGarvey, Samantha Thulborn, Timonthy S C Hinks, Rekha Chaudhuri, Clare Connolly, Gareth Hynes, Ian D. Pavord, Liam G Heaney, Rahul Shrimanker
Publikováno v:
Allergy and immunology.
Autor:
Jonathan Schelfhout, Alyn H. Morice, Allison Martin Nguyen, A. Tzontcheva, Peter V. Dicpinigaitis, David Muccino, Ian D. Pavord, Jaclyn A. Smith, Qing Li, Lorcan McGarvey, Surinder S. Birring, Carmen La Rosa
Publikováno v:
Monitoring airway disease.
Autor:
Qing Li, Ian D. Pavord, Allison Martin Nguyen, Peter V. Dicpinigaitis, Carmen La Rosa, Alyn H. Morice, David Muccino, Jaclyn A. Smith, Lorcan McGarvey, Surinder S. Birring, Jonathan Schelfhout, A. Tzontcheva
Publikováno v:
Monitoring airway disease.