Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wolk, David"'
Autor:
Duong, Michael Tran, Das, Sandhitsu R, Lyu, Xueying, Xie, Long, Richardson, Hayley, Xie, Sharon X, Yushkevich, Paul A, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Wolk, David A, Nasrallah, Ilya M
Publikováno v:
Nature communications, vol 13, iss 1
Alzheimer's disease (AD) is defined by amyloid (A) and tau (T) pathologies, with T better correlated to neurodegeneration (N). However, T and N have complex regional relationships in part related to non-AD factors that influence N. With machine learn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::999e62fccb84bbd419e5f8eab2f63a9a
https://escholarship.org/uc/item/29h7w9rw
https://escholarship.org/uc/item/29h7w9rw
Autor:
Das, Sandhitsu R, Lyu, Xueying, Duong, Michael Tran, Xie, Long, McCollum, Lauren, de Flores, Robin, DiCalogero, Michael, Irwin, David J, Dickerson, Bradford C, Nasrallah, Ilya M, Yushkevich, Paul A, Wolk, David A, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Annals of neurology, vol 90, iss 5
ObjectiveTau neurofibrillary tangles (T) are the primary driver of downstream neurodegeneration (N) and subsequent cognitive impairment in Alzheimer's disease (AD). However, there is substantial variability in the T-N relationship - manifested in hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::61a1f9c7a9b14baec7fa9a3cc39d2fe4
https://escholarship.org/uc/item/28m3w3x9
https://escholarship.org/uc/item/28m3w3x9
Autor:
Habes, Mohamad, Pomponio, Raymond, Shou, Haochang, Doshi, Jimit, Mamourian, Elizabeth, Erus, Guray, Nasrallah, Ilya, Launer, Lenore J, Rashid, Tanweer, Bilgel, Murat, Fan, Yong, Toledo, Jon B, Yaffe, Kristine, Sotiras, Aristeidis, Srinivasan, Dhivya, Espeland, Mark, Masters, Colin, Maruff, Paul, Fripp, Jurgen, Völzk, Henry, Johnson, Sterling C, Morris, John C, Albert, Marilyn S, Miller, Michael I, Bryan, R Nick, Grabe, Hans J, Resnick, Susan M, Wolk, David A, Davatzikos, Christos, iSTAGING consortium, the Preclinical AD consortium, the ADNI, and the CARDIA studies
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 17, iss 1
IntroductionRelationships between brain atrophy patterns of typical aging and Alzheimer's disease (AD), white matter disease, cognition, and AD neuropathology were investigated via machine learning in a large harmonized magnetic resonance imaging dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9259c9b59a23c0410baedf64930bb178
https://escholarship.org/uc/item/7jn344p2
https://escholarship.org/uc/item/7jn344p2
Autor:
Coughlin, David G, Phillips, Jeffrey S, Roll, Emily, Peterson, Claire, Lobrovich, Rebecca, Rascovsky, Katya, Ungrady, Molly, Wolk, David A, Das, Sandhitsu, Weintraub, Daniel, Lee, Edward B, Trojanowski, John Q, Shaw, Leslie M, Vaishnavi, Sanjeev, Siderowf, Andrew, Nasrallah, Ilya M, Irwin, David J, McMillan, Corey T, Alzheimer’s Disease Neuroimaging Initiative
We compared regional retention of18F-flortaucipir between 20 patients with Lewy body disorders (LBD), 12 Alzheimer's disease patients with positive amyloid positron emission tomography (PET) scans (AD+Aβ) and 15 healthy controls with negative amyloi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::3ad584cf6876b329a063dfb541c1dffb
https://escholarship.org/uc/item/5sq0n55h
https://escholarship.org/uc/item/5sq0n55h
Autor:
Zhou, Hucheng, Jiang, Jiehui, Lu, Jiaying, Wang, Min, Zhang, Huiwei, Zuo, Chuantao, Weiner, Michael W, Aisen, Paul, Petersen, Ronald, Jr, Jack Clifford R, Jagust, William, Trojanowki, John Q, Toga, Arthur W, Beckett, Laurel, Green, Robert C, Saykin, Andrew J, Morris, John, Shaw, Leslie M, Khachaturian, Zaven, Sorensen, Greg, Carrillo, Maria, Kuller, Lew, Raichle, Marc, Paul, Steven, Davies, Peter, Fillit, Howard, Hefti, Franz, Holtzman, David, Mesulam, M Marcel, Potter, William, Snyder, Peter, Lilly, Eli, Montine, Tom, Jimenez, Gustavo, Donohue, Michael, Gessert, Devon, Harless, Kelly, Salazar, Jennifer, Cabrera, Yuliana, Walter, Sarah, Hergesheimer, Lindsey, Harvey, Danielle, Bernstein, Matthew, Fox, Nick, Thompson, Paul, Schuff, Norbert, DeCArli, Charles, Borowski, Bret, Gunter, Jeff, Senjem, Matt, Vemuri, Prashanthi, Jones, David, Kantarci, Kejal, Ward, Chad, Koeppe, Robert A, Foster, Norm, Reiman, Eric M, Chen, Kewei, Mathis, Chet, Logovinsky, Veronika, Morris, John C, Cairns, Nigel J, Franklin, Erin, Taylor-Reinwald, Lisa, Lee, Virginia, Korecka, Magdalena, Figurski, Michal, Crawford, Karen, Neu, Scott, Foroud, Tatiana M, Potkin, Steven, Shen, Li, Faber, Kelley, Kim, Sungeun, Nho, Kwangsik, Thal, Lean, Thal, Leon, Buckholtz, Neil, Snyder, Peter J, Albert, Marilyn, Frank, Richard, Hsiao, John, Landau, Susan, Quinn, Joseph, Silbert, Lisa C, Lind, Betty, Kaye, Jeffrey A, Carter, Raina, Dolen, Sara, Schneider, Lon S, Pawluczyk, Sonia, Becerra, Mauricio, Teodoro, Liberty, Spann, Bryan M, Brewer, James, Vanderswag, Helen, Fleisher, Adam, Ziolkowski, Jaimie, Heidebrink, Judith L, Lord, Joanne L, Mason, Sara S, Albers, Colleen S, Knopman, David, Johnson, Kris, Villanueva-Meyer, Javier, Pavlik, Valory, Pacini, Nathaniel, Lamb, Ashley, Kass, Joseph S, Doody, Rachelle S, Shibley, Victoria, Chowdhury, Munir, Rountree, Susan, Dang, Mimi, Stem, Yaakov, Honig, Lawrence S, Bell, Karen L, Yeh, Randy, Ances, Beau, Winkfield, David, Carroll, Maria, Oliver, Angela, Creech, Mary L, Mintun, Mark A, Schneider, Stacy, Marson, Daniel, Geldmacher, David, Love, Marissa Natelson, Griffith, Randall, Clark, David, Brockington, John, Grossman, Hillel, Mitsis, Effie, Shah, Raj C, Lamar, Melissa, Samuels, Patricia, Duara, Ranjan, Greig-Custo, Maria T, Rodriguez, Rosemarie, Onyike, Chiadi, II, D'Agostino Daniel, Kielb, Stephanie, Sadowski, Martin, Sheikh, Mohammed O, Singleton-Garvin, Jamika, Ulysse, Anaztasia, Gaikwad, Mrunalini, Doraiswamy, P Murali, Petrella, Jeffrey R, James, Olga, Borges-Neto, Salvador, Wong, Terence Z, Coleman, Edward, Karlawish, Jason H, Wolk, David A, Vaishnavi, Sanjeev, Clark, Christopher M, Arnold, Steven E, Smith, Charles D, Jicha, Greg, Hardy, Peter, El Khouli, Riham, Oates, Elizabeth, Conrad, Gary, Lopez, Oscar L, Oakley, MaryAnn, Simpson, Donna M, Porsteinsson, Anton P, Martin, Kim, Kowalksi, Nancy, Keltz, Melanie, Goldstein, Bonnie S, Makino, Kelly M, Ismail, M Saleem, Brand, Connie, Thai, Gaby, Pierce, Aimee, Yanez, Beatriz, Sosa, Elizabeth, Witbracht, Megan, Womack, Kyle, Mathews, Dana, Quiceno, Mary, Levey, Allan I, Lah, James J, Cellar, Janet S, Burns, Jeffrey M, Swerdlow, Russell H, Brooks, William M, Woo, Ellen, Silverman, Daniel HS, Teng, Edmond, Kremen, Sarah, Apostolova, Liana, Tingus, Kathleen, Lu, Po H, Bartzokis, George, Graff-Radford, Neill R, Parfitt, Francine, Poki-Walker, Kim, Farlow, Martin R, Hake, Ann Marie, Matthews, Brandy R, Brosch, Jared R, Herring, Scott, van Dyck, Christopher H, Carson, Richard E, Varma, Pradeep, Chertkow, Howard, Bergman, Howard, Hosein, Chris, Black, Sandra, Stefanovic, Bojana, Heyn, Chris Chinthaka, Hsiung, Ging-Yuek Robin, Mudge, Benita, Sossi, Vesna, Feldman, Howard, Assaly, Michele, Finger, Elizabeth, Pasternack, Stephen, Pavlosky, William, Rachinsky, Irina, Drost, Dick, Kertesz, Andrew, Bernick, Charles, Munic, Donna, Mesulam, Marek-Marsel, Rogalski, Emily, Lipowski, Kristine, Weintraub, Sandra, Bonakdarpour, Borna, Kerwin, Diana, Wu, Chuang-Kuo, Johnson, Nancy, Sadowsky, Carl, Villena, Teresa, Turner, Raymond Scott, Johnson, Kathleen, Reynolds, Brigid, Sperling, Reisa A, Johnson, Keith A, Marshall, Gad A, Yesavage, Jerome, Taylor, Joy L, Chao, Steven, Lane, Barton, Rosen, Allyson, Tinklenberg, Jared, Zamrini, Edward, Belden, Christine M, Sirrel, Sherye A, Kowall, Neil, Killiany, Ronald, Budson, Andrew E, Norbash, Alexander, Johnson, Patricia Lynn, Obisesan, Thomas O, Oyonumo, Ntekim E, Allard, Joanne, Nlana, Olu Ogu, Lerner, Alan, Ogrocki, Paula, Tatsuoka, Curtis, Fatica, Parianne, Fletcher, Evan, Maillard, Pauline, Olichney, John, Carmichael, Owen, Kittur, Smita, Borrie, Michael, Lee, T-Y, Bartha, Rob, Johnson, Sterling, Asthana, Sanjay, Carlsson, Cynthia M, Tariot, Pierre, Burke, Anna, Hetelle, Joel, DeMarco, Kathryn, Trncic, Nadira, Reeder, Stephanie, Bates, Vernice, Capote, Horacio, Rainka, Michelle, Scharre, Douglas W, Kataki, Maria, Tarawneh, Rawan, Zimmerman, Earl A, Celmins, Dzintra, Hart, David, Pearlson, Godfrey D, Blank, Karen, Anderson, Karen, Flashman, Laura A, Seltzer, Marc, Hynes, Mary L, Santulli, Robert B, Sink, Kaycee M, Yang, Mia, Mintz, Akiva, Ott, Brian R, Tremont, Geoffrey, Daiello, Lori A, Bodge, Courtney, Salloway, Stephen, Malloy, Paul, Correia, Stephen, Lee, Athena, Rosen, Howard J, Miller, Bruce L, Perry, David, Mintzer, Jacobo, Spicer, Kenneth, Bachman, David, Pasternak, Stephen, Rogers, John, Pomara, Nunzio, Hernando, Raymundo, Sarrael, Antero, Miller, Delwyn D, Smith, Karen Ekstam, Koleva, Hristina, Nam, Ki Won, Shim, Hyungsub, Schultz, Susan K, Relkin, Norman, Chiang, Gloria, Lin, Michael, Ravdin, Lisa, Smith, Amanda, Leach, Christi, Raj, Balebail Ashok, Fargher, Kristin, Neylan, Thomas, Grafman, Jordan, Hergesheimen, Lindsey, Hayes, Jacqueline, Finley, Shannon, Householder, Erin, Fleischman, Debra, Arfanakis, Konstantinos, Varon, Daniel, Greig, Maria T, Goldstein, Bonnie, Martin, Kimberly S, Potkin, Steven G, Preda, Adrian, Nguyen, Dana, Massoglia, Dino, Brawman-Mintzer, Olga, Martinez, Walte R, Rosen, Howard, Behan, Kelly, Marshall, Gad, Sabbagh, Marwan N, Jacobson, Sandra A, Wolday, Saba, Johnson, Sterling C, Fruehling, J Jay, Harding, Sandra, Peskind, Elaine R, Petrie, Eric C, Li, Gail, Yesavage, Jerome A, Furst, Ansgar J, Mackin, Scott, Raman, Rema, Drake, Erin, Donohue, Mike, Shaffe, Elizabeth, Nelson, Craig, Bickford, David, Butters, Meryl, Zmuda, Michelle, Reyes, Denise, Nudelman, Kelly N, Au, Yiu Ho, Scherer, Kelly, Catalinotto, Daniel, Stark, Samuel, Ong, Elise, Fernandez, Dariella, Initia, Alzheimers Dis Neuroimaging
Publikováno v:
Zhou, Hucheng; Jiang, Jiehui; Lu, Jiaying; Wang, Min; Zhang, Huiwei; Zuo, Chuantao; et al.(2019). Dual-Model Radiomic Biomarkers Predict Development of Mild Cognitive Impairment Progression to Alzheimer's Disease. FRONTIERS IN NEUROSCIENCE, 12, 1045. doi: 10.3389/fnins.2018.01045. UCSF: Retrieved from: http://www.escholarship.org/uc/item/6wg4q4rp
Predicting progression of mild cognitive impairment (MCI) to Alzheimer's disease (AD) is clinically important. In this study, we propose a dual-model radiomic analysis with multivariate Cox proportional hazards regression models to investigate promis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::d2a7658ec8fa2244b65b669e68ca79e9
http://www.escholarship.org/uc/item/6wg4q4rp
http://www.escholarship.org/uc/item/6wg4q4rp
Autor:
Wolk, David A, Das, Sandhitsu R, Mueller, Susanne G, Weiner, Michael W, Yushkevich, Paul A, Alzheimer's Disease Neuroimaging Initiative
Autopsy studies of Alzheimer's disease (AD) have found that neurofibrillary tangle (NFT) pathology of the medial temporal lobe (MTL) demonstrates selective topography with relatively stereotyped subregional involvement at early disease stages, prompt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::6faa83db3c1a2f9712fdbfe39105f3c9
https://escholarship.org/uc/item/32m781zx
https://escholarship.org/uc/item/32m781zx
Autor:
Wisse, Laura EM, Butala, Nirali, Das, Sandhitsu R, Davatzikos, Christos, Dickerson, Bradford C, Vaishnavi, Sanjeev N, Yushkevich, Paul A, Wolk, David A, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Neurobiology of aging, vol 36, iss 12
We aim to better characterize mild cognitive impairment (MCI) patients with suspected non-Alzheimer's disease (AD) pathology (SNAP) based on their longitudinal outcome, cognition, biofluid, and neuroimaging profile. MCI participants (n = 361) from AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::4c722eea2b5dad94b8c550eaeb2368eb
https://escholarship.org/uc/item/8538s14g
https://escholarship.org/uc/item/8538s14g
Autor:
Ossenkoppele, Rik, Jansen, Willemijn J, Rabinovici, Gil D, Knol, Dirk L, van der Flier, Wiesje M, van Berckel, Bart NM, Scheltens, Philip, Visser, Pieter Jelle, Amyloid PET Study Group, Verfaillie, Sander CJ, Zwan, Marissa D, Adriaanse, Sofie M, Lammertsma, Adriaan A, Barkhof, Frederik, Jagust, William J, Miller, Bruce L, Rosen, Howard J, Landau, Susan M, Villemagne, Victor L, Rowe, Christopher C, Lee, Dong Y, Na, Duk L, Seo, Sang W, Sarazin, Marie, Roe, Catherine M, Sabri, Osama, Barthel, Henryk, Koglin, Norman, Hodges, John, Leyton, Cristian E, Vandenberghe, Rik, van Laere, Koen, Drzezga, Alexander, Forster, Stefan, Grimmer, Timo, Sánchez-Juan, Pascual, Carril, Jose M, Mok, Vincent, Camus, Vincent, Klunk, William E, Cohen, Ann D, Meyer, Philipp T, Hellwig, Sabine, Newberg, Andrew, Frederiksen, Kristian S, Fleisher, Adam S, Mintun, Mark A, Wolk, David A, Nordberg, Agneta, Rinne, Juha O, Chételat, Gaël, Lleo, Alberto, Blesa, Rafael, Fortea, Juan, Madsen, Karine, Rodrigue, Karen M, Brooks, David J
Publikováno v:
JAMA, vol 313, iss 19
ImportanceAmyloid-β positron emission tomography (PET) imaging allows in vivo detection of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its diagnostic utility is still unclear because amyloid plaques also occur in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4d92d5864552cdad53cbeae5b64cae25
https://escholarship.org/uc/item/1ds975nj
https://escholarship.org/uc/item/1ds975nj
Autor:
Toledo, Jon B, Da, Xiao, Weiner, Michael W, Wolk, David A, Xie, Sharon X, Arnold, Steven E, Davatzikos, Christos, Shaw, Leslie M, Trojanowski, John Q, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Acta neuropathologica, vol 127, iss 5
Apolipoprotein E (APOE) ε4 allele is the most important genetic risk factor for Alzheimer's disease (AD) and it is thought to do so by modulating levels of its product, apolipoprotein E (Apo-E), and regulating amyloid-β (Aβ) clearance. However, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9aadd84912f1488a5449f1c698ead4c0
https://escholarship.org/uc/item/9kq5b83f
https://escholarship.org/uc/item/9kq5b83f
Autor:
Arnold, Steven E, Toledo, Jon B, Appleby, Dina H, Xie, Sharon X, Wang, Li-San, Baek, Young, Wolk, David A, Lee, Edward B, Miller, Bruce L, Lee, Virginia M-Y, Trojanowski, John Q
Publikováno v:
The Journal of comparative neurology, vol 521, iss 18
An understanding of the anatomic distributions of major neurodegenerative disease lesions is important to appreciate the differential clinical profiles of these disorders and to serve as neuropathological standards for emerging molecular neuroimaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::a86b40fd5e1a099ec9119bf563c958f8
https://escholarship.org/uc/item/748895v5
https://escholarship.org/uc/item/748895v5