Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tuomi T"'
Autor:
Albrechtsen, A, Grarup, N, Li, Y, Sparsø, T, Tian, G, Cao, H, Jiang, T, Kim, SY, Korneliussen, T, Li, Q, Nie, C, Wu, R, Skotte, L, Morris, AP, Ladenvall, C, Cauchi, S, Stančáková, A, Andersen, G, Astrup, A, Banasik, K, Bennett, AJ, Bolund, L, Charpentier, G, Chen, Y, Dekker, JM, Doney, ASF, Dorkhan, M, Forsen, T, Frayling, TM, Groves, CJ, Gui, Y, Hallmans, G, Hattersley, AT, He, K, Hitman, GA, Holmkvist, J, Huang, S, Jiang, H, Jin, X, Justesen, JM, Kristiansen, K, Kuusisto, J, Lajer, M, Lantieri, O, Li, W, Liang, H, Liao, Q, Liu, X, Ma, T, Ma, X, Manijak, MP, Marre, M, Mokrosiński, J, Morris, AD, Mu, B, Nielsen, AA, Nijpels, G, Nilsson, P, Palmer, CNA, Rayner, NW, Renström, F, Ribel-Madsen, R, Robertson, N, Rolandsson, O, Rossing, P, Schwartz, TW, D.E.S.I.R. Study Group, Slagboom, PE, Sterner, M, DIAGRAM Consortium, Tang, M, Tarnow, L, Tuomi, T, van't Riet, E, van Leeuwen, N, Varga, TV, Vestmar, MA, Walker, M, Wang, B, Wang, Y, Wu, H, Xi, F, Yengo, L, Yu, C, Zhang, X, Zhang, J, Zhang, Q, Zhang, W, Zheng, H, Zhou, Y, Altshuler, D, 't Hart, LM, Franks, PW, Balkau, B, Froguel, P, McCarthy, MI, Laakso, M, Groop, L, Christensen, C, Brandslund, I
Publikováno v:
Diabetologia, vol 56, iss 2
Aims/hypothesisHuman complex metabolic traits are in part regulated by genetic determinants. Here we applied exome sequencing to identify novel associations of coding polymorphisms at minor allele frequencies (MAFs) >1% with common metabolic phenotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::eadd4f823fd99139c2e5a47e159c558b
https://escholarship.org/uc/item/6r98p2fn
https://escholarship.org/uc/item/6r98p2fn
Autor:
Strawbridge, RJ, Dupuis, J, Prokopenko, I, Barker, A, Ahlqvist, E, Rybin, D, Petrie, JR, Travers, ME, Bouatia-Naji, N, Dimas, AS, Nica, A, Wheeler, E, Chen, H, Voight, BF, Taneera, J, Kanoni, S, Peden, JF, Turrini, F, Gustafsson, S, Zabena, C, Almgren, P, Barker, DJP, Barnes, D, Dennison, EM, Eriksson, JG, Eriksson, P, Eury, E, Folkersen, L, Fox, CS, Frayling, TM, Goel, A, Gu, HF, Horikoshi, M, Isomaa, B, Jackson, AU, Jameson, KA, Kajantie, E, Kerr-Conte, J, Kuulasmaa, T, Kuusisto, J, Loos, RJF, Luan, J, Makrilakis, K, Manning, AK, Martínez-Larrad, MT, Narisu, N, Mannila, MN, Öhrvik, J, Osmond, C, Pascoe, L, Payne, F, Sayer, AA, Sennblad, B, Silveira, A, Stančcáková, A, Stirrups, K, Swift, AJ, Syvänen, AC, Tuomi, T
Publikováno v:
Strawbridge, RJ; Dupuis, J; Prokopenko, I; Barker, A; Ahlqvist, E; Rybin, D; et al.(2011). Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes, 60(10), 2624-2634. doi: 10.2337/db11-0415. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9354m27f
© 2011 by the American Diabetes Association. OBJECTIVE - Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired b-cell function, raised glucose levels, insulin resistance, and typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::f18a2da9a72af766139d5c40fdbb966c
http://www.escholarship.org/uc/item/9354m27f
http://www.escholarship.org/uc/item/9354m27f