Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Laurie, Cathy C."'
Autor:
Wainschtein, Pierrick, Jain, Deepti, Zheng, Zhili, TOPMed Anthropometry Working Group, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Cupples, L Adrienne, Shadyab, Aladdin H, McKnight, Barbara, Shoemaker, Benjamin M, Mitchell, Braxton D, Psaty, Bruce M, Kooperberg, Charles, Liu, Ching-Ti, Albert, Christine M, Roden, Dan, Chasman, Daniel I, Darbar, Dawood, Lloyd-Jones, Donald M, Arnett, Donna K, Regan, Elizabeth A, Boerwinkle, Eric, Rotter, Jerome I, O'Connell, Jeffrey R, Yanek, Lisa R, de Andrade, Mariza, Allison, Matthew A, McDonald, Merry-Lynn N, Chung, Mina K, Fornage, Myriam, Chami, Nathalie, Smith, Nicholas L, Ellinor, Patrick T, Vasan, Ramachandran S, Mathias, Rasika A, Loos, Ruth JF, Rich, Stephen S, Lubitz, Steven A, Heckbert, Susan R, Redline, Susan, Guo, Xiuqing, Chen, Y-D Ida, Laurie, Cecelia A, Hernandez, Ryan D, McGarvey, Stephen T, Goddard, Michael E, Laurie, Cathy C, North, Kari E, Lange, Leslie A, Weir, Bruce S, Yengo, Loic, Yang, Jian, Visscher, Peter M
Publikováno v:
Nature genetics, vol 54, iss 3
Analyses of data from genome-wide association studies on unrelated individuals have shown that, for human traits and diseases, approximately one-third to two-thirds of heritability is captured by common SNPs. However, it is not known whether the rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::5a76ff8abdfb6c493df757629758e0bb
https://escholarship.org/uc/item/4t79z6mp
https://escholarship.org/uc/item/4t79z6mp
Autor:
Hu, Yao, Stilp, Adrienne M, McHugh, Caitlin P, Rao, Shuquan, Jain, Deepti, Zheng, Xiuwen, Lane, John, Méric de Bellefon, Sébastian, Raffield, Laura M, Chen, Ming-Huei, Yanek, Lisa R, Wheeler, Marsha, Yao, Yao, Ren, Chunyan, Broome, Jai, Moon, Jee-Young, de Vries, Paul S, Hobbs, Brian D, Sun, Quan, Surendran, Praveen, Brody, Jennifer A, Blackwell, Thomas W, Choquet, Hélène, Ryan, Kathleen, Duggirala, Ravindranath, Heard-Costa, Nancy, Wang, Zhe, Chami, Nathalie, Preuss, Michael H, Min, Nancy, Ekunwe, Lynette, Lange, Leslie A, Cushman, Mary, Faraday, Nauder, Curran, Joanne E, Almasy, Laura, Kundu, Kousik, Smith, Albert V, Gabriel, Stacey, Rotter, Jerome I, Fornage, Myriam, Lloyd-Jones, Donald M, Vasan, Ramachandran S, Smith, Nicholas L, North, Kari E, Boerwinkle, Eric, Becker, Lewis C, Lewis, Joshua P, Abecasis, Goncalo R, Hou, Lifang, O'Connell, Jeffrey R, Morrison, Alanna C, Beaty, Terri H, Kaplan, Robert, Correa, Adolfo, Blangero, John, Jorgenson, Eric, Psaty, Bruce M, Kooperberg, Charles, Walton, Russell T, Kleinstiver, Benjamin P, Tang, Hua, Loos, Ruth JF, Soranzo, Nicole, Butterworth, Adam S, Nickerson, Debbie, Rich, Stephen S, Mitchell, Braxton D, Johnson, Andrew D, Auer, Paul L, Li, Yun, Mathias, Rasika A, Lettre, Guillaume, Pankratz, Nathan, Laurie, Cathy C, Laurie, Cecelia A, Bauer, Daniel E, Conomos, Matthew P, Reiner, Alexander P, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
Publikováno v:
American journal of human genetics, vol 108, iss 5
Whole-genome sequencing (WGS), a powerful tool for detecting novel coding and non-coding disease-causing variants, has largely been applied to clinical diagnosis of inherited disorders. Here we leveraged WGS data in up to 62,653 ethnically diverse pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::445eb02b1c412ec0c77798d591b7420a
https://escholarship.org/uc/item/24j6v92r
https://escholarship.org/uc/item/24j6v92r
Autor:
Li, Xihao, Li, Zilin, Zhou, Hufeng, Gaynor, Sheila M, Liu, Yaowu, Chen, Han, Sun, Ryan, Dey, Rounak, Arnett, Donna K, Aslibekyan, Stella, Ballantyne, Christie M, Bielak, Lawrence F, Blangero, John, Boerwinkle, Eric, Bowden, Donald W, Broome, Jai G, Conomos, Matthew P, Correa, Adolfo, Cupples, L Adrienne, Curran, Joanne E, Freedman, Barry I, Guo, Xiuqing, Hindy, George, Irvin, Marguerite R, Kardia, Sharon LR, Kathiresan, Sekar, Khan, Alyna T, Kooperberg, Charles L, Laurie, Cathy C, Liu, X Shirley, Mahaney, Michael C, Manichaikul, Ani W, Martin, Lisa W, Mathias, Rasika A, McGarvey, Stephen T, Mitchell, Braxton D, Montasser, May E, Moore, Jill E, Morrison, Alanna C, O'Connell, Jeffrey R, Palmer, Nicholette D, Pampana, Akhil, Peralta, Juan M, Peyser, Patricia A, Psaty, Bruce M, Redline, Susan, Rice, Kenneth M, Rich, Stephen S, Smith, Jennifer A, Tiwari, Hemant K, Tsai, Michael Y, Vasan, Ramachandran S, Wang, Fei Fei, Weeks, Daniel E, Weng, Zhiping, Wilson, James G, Yanek, Lisa R, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Lipids Working Group, Neale, Benjamin M, Sunyaev, Shamil R, Abecasis, Gonçalo R, Rotter, Jerome I, Willer, Cristen J, Peloso, Gina M, Natarajan, Pradeep, Lin, Xihong
Publikováno v:
Nature genetics, vol 52, iss 9
Large-scale whole-genome sequencing studies have enabled the analysis of rare variants (RVs) associated with complex phenotypes. Commonly used RV association tests have limited scope to leverage variant functions. We propose STAAR (variant-set test f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e52aef530ecaa2ce04de16503b6abfa5
https://escholarship.org/uc/item/61s9b995
https://escholarship.org/uc/item/61s9b995
Autor:
Jian, Xueqiu, Sofer, Tamar, Tarraf, Wassim, Bressler, Jan, Faul, Jessica D, Zhao, Wei, Ratliff, Scott M, Lamar, Melissa, Launer, Lenore J, Laurie, Cathy C, Schneiderman, Neil, Weir, David R, Wright, Clinton B, Yaffe, Kristine, Zeng, Donglin, DeCarli, Charles, Mosley, Thomas H, Smith, Jennifer A, González, Hector M, Fornage, Myriam
Publikováno v:
Translational psychiatry, vol 10, iss 1
Cognitive function such as reasoning, attention, memory, and language is strongly correlated with brain aging. Compared to non-Hispanic whites, Hispanics/Latinos have a higher risk of cognitive impairment and dementia. The genetic determinants of cog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::3320d0aac591c1939135a4c4499778a6
https://escholarship.org/uc/item/1x8741h2
https://escholarship.org/uc/item/1x8741h2
Autor:
Jian, Xueqiu, Sofer, Tamar, Tarraf, Wassim, Bressler, Jan, Faul, Jessica D, Zhao, Wei, Ratliff, Scott M, Lamar, Melissa, Launer, Lenore J, Laurie, Cathy C, Schneiderman, Neil, Weir, David R, Wright, Clinton B, Yaffe, Kristine, Zeng, Donglin, DeCarli, Charles, Mosley, Thomas H, Smith, Jennifer A, González, Hector M, Fornage, Myriam
Publikováno v:
Translational psychiatry, vol 10, iss 1
Cognitive function such as reasoning, attention, memory, and language is strongly correlated with brain aging. Compared to non-Hispanic whites, Hispanics/Latinos have a higher risk of cognitive impairment and dementia. The genetic determinants of cog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::b1e43b4785753a7e15637b3dc3783bbf
https://escholarship.org/uc/item/1x8741h2
https://escholarship.org/uc/item/1x8741h2
Autor:
Chen, Han, Huffman, Jennifer E, Brody, Jennifer A, Wang, Chaolong, Lee, Seunggeun, Li, Zilin, Gogarten, Stephanie M, Sofer, Tamar, Bielak, Lawrence F, Bis, Joshua C, Blangero, John, Bowler, Russell P, Cade, Brian E, Cho, Michael H, Correa, Adolfo, Curran, Joanne E, de Vries, Paul S, Glahn, David C, Guo, Xiuqing, Johnson, Andrew D, Kardia, Sharon, Kooperberg, Charles, Lewis, Joshua P, Liu, Xiaoming, Mathias, Rasika A, Mitchell, Braxton D, O'Connell, Jeffrey R, Peyser, Patricia A, Post, Wendy S, Reiner, Alex P, Rich, Stephen S, Rotter, Jerome I, Silverman, Edwin K, Smith, Jennifer A, Vasan, Ramachandran S, Wilson, James G, Yanek, Lisa R, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, Redline, Susan, Smith, Nicholas L, Boerwinkle, Eric, Borecki, Ingrid B, Cupples, L Adrienne, Laurie, Cathy C, Morrison, Alanna C, Rice, Kenneth M, Lin, Xihong
Publikováno v:
American journal of human genetics, vol 104, iss 2
With advances in whole-genome sequencing (WGS) technology, more advanced statistical methods for testing genetic association with rare variants are being developed. Methods in which variants are grouped for analysis are also known as variant-set, gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::e04981594ad18439135805d7f8a27f68
https://escholarship.org/uc/item/1918z4zr
https://escholarship.org/uc/item/1918z4zr
Autor:
Wyss, Annah B, Sofer, Tamar, Lee, Mi Kyeong, Terzikhan, Natalie, Nguyen, Jennifer N, Lahousse, Lies, Latourelle, Jeanne C, Smith, Albert Vernon, Bartz, Traci M, Feitosa, Mary F, Gao, Wei, Ahluwalia, Tarunveer S, Tang, Wenbo, Oldmeadow, Christopher, Duan, Qing, de Jong, Kim, Wojczynski, Mary K, Wang, Xin-Qun, Noordam, Raymond, Hartwig, Fernando Pires, Jackson, Victoria E, Wang, Tianyuan, Obeidat, Ma'en, Hobbs, Brian D, Huan, Tianxiao, Gui, Hongsheng, Parker, Margaret M, Hu, Donglei, Mogil, Lauren S, Kichaev, Gleb, Jin, Jianping, Graff, Mariaelisa, Harris, Tamara B, Kalhan, Ravi, Heckbert, Susan R, Paternoster, Lavinia, Burkart, Kristin M, Liu, Yongmei, Holliday, Elizabeth G, Wilson, James G, Vonk, Judith M, Sanders, Jason L, Barr, R Graham, de Mutsert, Renée, Menezes, Ana Maria Baptista, Adams, Hieab HH, van den Berge, Maarten, Joehanes, Roby, Levin, Albert M, Liberto, Jennifer, Launer, Lenore J, Morrison, Alanna C, Sitlani, Colleen M, Celedón, Juan C, Kritchevsky, Stephen B, Scott, Rodney J, Christensen, Kaare, Rotter, Jerome I, Bonten, Tobias N, Wehrmeister, Fernando César, Bossé, Yohan, Xiao, Shujie, Oh, Sam, Franceschini, Nora, Brody, Jennifer A, Kaplan, Robert C, Lohman, Kurt, McEvoy, Mark, Province, Michael A, Rosendaal, Frits R, Taylor, Kent D, Nickle, David C, Williams, L Keoki, Burchard, Esteban G, Wheeler, Heather E, Sin, Don D, Gudnason, Vilmundur, North, Kari E, Fornage, Myriam, Psaty, Bruce M, Myers, Richard H, O'Connor, George, Hansen, Torben, Laurie, Cathy C, Cassano, Patricia A, Sung, Joohon, Kim, Woo Jin, Attia, John R, Lange, Leslie, Boezen, H Marike, Thyagarajan, Bharat, Rich, Stephen S, Mook-Kanamori, Dennis O, Horta, Bernardo Lessa, Uitterlinden, André G, Im, Hae Kyung, Cho, Michael H, Brusselle, Guy G, Gharib, Sina A
Publikováno v:
Nature communications, vol 9, iss 1
Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of European ancestry populations. We extend previous research by meta-analyzing genome-wide association studies of 1000 Genomes imputed variants in relation to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3eb4bf21a2610e097d918650bc37e1e5
https://escholarship.org/uc/item/4cx2v3pk
https://escholarship.org/uc/item/4cx2v3pk
Autor:
Napier, Melanie D, Franceschini, Nora, Gondalia, Rahul, Stewart, James D, Méndez-Giráldez, Raúl, Sitlani, Colleen M, Seyerle, Amanda A, Highland, Heather M, Li, Yun, Wilhelmsen, Kirk C, Yan, Song, Duan, Qing, Roach, Jeffrey, Yao, Jie, Guo, Xiuqing, Taylor, Kent D, Heckbert, Susan R, Rotter, Jerome I, North, Kari E, Reiner, Alexander P, Zhang, Zhu-Ming, Tinker, Lesley F, Liao, Duanping, Laurie, Cathy C, Gogarten, Stephanie M, Lin, Henry J, Brody, Jennifer A, Bartz, Traci M, Psaty, Bruce M, Sotoodehnia, Nona, Soliman, Elsayed Z, Avery, Christy L, Whitsel, Eric A
Publikováno v:
Scientific reports, vol 8, iss 1
The genetic basis of supraventricular and ventricular ectopy (SVE, VE) remains largely uncharacterized, despite established genetic mechanisms of arrhythmogenesis. To identify novel genetic variants associated with SVE/VE in ancestrally diverse human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::e13801ed31d5851184fd827904893fa8
https://escholarship.org/uc/item/74n979kg
https://escholarship.org/uc/item/74n979kg
Autor:
Kerr, Kathleen F, Avery, Christy L, Lin, Henry J, Raffield, Laura M, Zhang, Qian S, Browning, Brian L, Browning, Sharon R, Conomos, Matthew P, Gogarten, Stephanie M, Laurie, Cathy C, Sofer, Tamar, Thornton, Timothy A, Hohensee, Chancellor, Jackson, Rebecca D, Kooperberg, Charles, Li, Yun, Méndez-Giráldez, Raúl, Perez, Marco V, Peters, Ulrike, Reiner, Alexander P, Zhang, Zhu-Ming, Yao, Jie, Sotoodehnia, Nona, Taylor, Kent D, Guo, Xiuqing, Lange, Leslie A, Soliman, Elsayed Z, Wilson, James G, Rotter, Jerome I, Heckbert, Susan R, Jain, Deepti, Whitsel, Eric A
Publikováno v:
Heart rhythm, vol 14, iss 11
BackgroundAlthough time-domain measures of heart rate variability (HRV) are used to estimate cardiac autonomic tone and disease risk in multiethnic populations, the genetic epidemiology of HRV in Hispanics/Latinos has not been characterized.Objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::d3d7049a65652edc4a7b3a7644bc3ab8
https://escholarship.org/uc/item/9pm036h3
https://escholarship.org/uc/item/9pm036h3
Autor:
Qi, Qibin, Stilp, Adrienne M, Sofer, Tamar, Moon, Jee-Young, Hidalgo, Bertha, Szpiro, Adam A, Wang, Tao, Ng, Maggie CY, Guo, Xiuqing, MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium, Chen, Yii-Der Ida, Taylor, Kent D, Aviles-Santa, M Larissa, Papanicolaou, George, Pankow, James S, Schneiderman, Neil, Laurie, Cathy C, Rotter, Jerome I, Kaplan, Robert C
Publikováno v:
Diabetes, vol 66, iss 5
Few genome-wide association studies (GWAS) of type 2 diabetes (T2D) have been conducted in U.S. Hispanics/Latinos of diverse backgrounds who are disproportionately affected by diabetes. We conducted a GWAS in 2,499 T2D case subjects and 5,247 control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::6fcb2ca7425dec06ea78fb3bf462fa01
https://escholarship.org/uc/item/28r6z0sq
https://escholarship.org/uc/item/28r6z0sq