Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ansuman T. Satpathy"'
Autor:
Ranit Kedmi, Tariq A. Najar, Kailin R. Mesa, Allyssa Grayson, Lina Kroehling, Yuhan Hao, Stephanie Hao, Maria Pokrovskii, Mo Xu, Jhimmy Talbot, Jiaxi Wang, Joe Germino, Caleb A. Lareau, Ansuman T. Satpathy, Mark S. Anderson, Terri M. Laufer, Iannis Aifantis, Juliet M. Bartleson, Paul M. Allen, Helena Paidassi, James M. Gardner, Marlon Stoeckius, Dan R. Littman
Publikováno v:
Nature, vol 610, iss 7933
Nature
Nature, 2022, 610 (7933), pp.737-743. ⟨10.1038/s41586-022-05089-y⟩
Nature
Nature, 2022, 610 (7933), pp.737-743. ⟨10.1038/s41586-022-05089-y⟩
The mutualistic relationship of gut-resident microbiota and the host immune system promotes homeostasis that ensures maintenance of the microbial community and of a largely non-aggressive immune cell compartment1,2. The consequences of disturbing thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84cab211530b906d38b48d797acdf56
https://escholarship.org/uc/item/4zh799vz
https://escholarship.org/uc/item/4zh799vz
Autor:
Jing Li, Maxim Zaslavsky, Yapeng Su, Jing Guo, Michael J. Sikora, Vincent van Unen, Asbjørn Christophersen, Shin-Heng Chiou, Liang Chen, Jiefu Li, Xuhuai Ji, Julie Wilhelmy, Alana M. McSween, Brad A. Palanski, Venkata Vamsee Aditya Mallajosyula, Nathan A. Bracey, Gopal Krishna R. Dhondalay, Kartik Bhamidipati, Joy Pai, Lucas B. Kipp, Jeffrey E. Dunn, Stephen L. Hauser, Jorge R. Oksenberg, Ansuman T. Satpathy, William H. Robinson, Cornelia L. Dekker, Lars M. Steinmetz, Chaitan Khosla, Paul J. Utz, Ludvig M. Sollid, Yueh-Hsiu Chien, James R. Heath, Nielsen Q. Fernandez-Becker, Kari C. Nadeau, Naresha Saligrama, Mark M. Davis
Publikováno v:
Science (New York, N.Y.), vol 376, iss 6590
In this work, we find that CD8 + T cells expressing inhibitory killer cell immunoglobulin-like receptors (KIRs) are the human equivalent of Ly49 + CD8 + regulatory T cells in mice and are increased in the blood and inflamed tissues of patients with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193563d69927496f79c565b0e039e25a
https://escholarship.org/uc/item/3hq5j2zz
https://escholarship.org/uc/item/3hq5j2zz
Autor:
Yani Peng, Alice Y. Chan, Jiaxi Wang, Dante D. Acenas, Jonah D Phipps, Quanming Shi, Alexander R Gupta, Ansuman T. Satpathy, James M. Gardner, Stanley Tamaki, Jeremy T. Warshauer, Jennifer A Smith, Julia A. Belk, Mark S. Anderson, Nikolaos Skartsis, Qizhi Tang
Publikováno v:
The Journal of experimental medicine, vol 218, iss 8
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Human STAT3 gain-of-function (GOF) mutations are linked to type 1 diabetes (T1D). This study establishes a STAT3-GOF mouse model that recapitulates the human T1D phenotype. STAT3-GOF drives cytotoxic CD8+ T cells that are resistant to terminal exhaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503ed38d817a28a117b35b4285c61762
https://escholarship.org/uc/item/61f9b398
https://escholarship.org/uc/item/61f9b398
Autor:
Ansuman T. Satpathy, K. Mark Ansel, Nicolas Bray, Jeffrey A. Bluestone, Alice Y. Chan, Graham J. Ray, Dimitre R. Simeonov, Kyle Kai-How Farh, Theodore L. Roth, Zhongmei Li, Michelle L.T. Nguyen, Mark J. Daly, William J. Greenleaf, Kathrin Schumann, Gemma L. Curie, Mark S. Anderson, Ruize Liu, Chun Jimmie Ye, Howard Y. Chang, Alexander Marson, Dmytro Lituiev, Therese Mitros, Nicki Naddaf, Jacob E. Corn, Victoria Tobin, Meena Subramaniam, Maxwell R. Mumbach, Hailiang Huang, Benjamin G. Gowen, Rachel E. Gate, Julia S. Chu, John D. Gagnon, Hong Ma, Frédéric Van Gool, Youjin Lee, Eric Boyer, Jonathan M. Woo, Mandy Boontanrart
Publikováno v:
Nature, vol 549, iss 7670
The majority of genetic variants associated with common human diseases map to enhancers, non-coding elements that shape cell-type-specific transcriptional programs and responses to extracellular cues. Systematic mapping of functional enhancers and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bd4330f085a76ad425b15ed30679cd
https://escholarship.org/uc/item/89t84794
https://escholarship.org/uc/item/89t84794
Autor:
Ashley Mahne, Allyson Spence, Qizhi Tang, Ansuman T. Satpathy, Vinh Son Nguyen, Kenneth M. Murphy, Joanna E. Klementowicz
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 199, iss 1
In NOD mice, CD11c+ cells increase greatly with islet inflammation and contribute to autoimmune destruction of pancreatic β cells. In this study, we investigated their origin and mechanism of recruitment. CD11c+ cells in inflamed islets resembled cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1ed9ed82b66cccff6a8885b788bf40
https://escholarship.org/uc/item/6230v2hq
https://escholarship.org/uc/item/6230v2hq
Autor:
Kenneth M. Murphy, Ansuman T. Satpathy, Todd C. Metzger, Arthur Weiss, Kristin V. Tarbell, Byron B. Au-Yeung, James M. Gardner, Anna K. Krawisz, Kellsey Johannes, Jeffrey D. Price, Wen Lu, Eileen J. McMahon, Mark S. Anderson
Publikováno v:
Immunity, vol 39, iss 3
The autoimmune regulator (Aire) is essential for prevention of autoimmunity; its role is best understood in the thymus, where it promotes self-tolerance through tissue-specific antigen (TSA) expression. Recently, extrathymic Aire-expressing cells (eT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40578f9f637da85cff2095a5a4de7f38
https://escholarship.org/uc/item/4f27c6c4
https://escholarship.org/uc/item/4f27c6c4