Zobrazeno 1 - 10
of 639
pro vyhledávání: ''
Autor:
Anirban Chakraborty, Nisha Tapryal, Azharul Islam, Altaf H. Sarker, Kodavati Manohar, Joy Mitra, Muralidhar L. Hegde, Tapas Hazra
Publikováno v:
The Journal of biological chemistry, vol 299, iss 3
A growing body of evidence indicates that RNA plays a critical role in orchestrating DNA double-strand break repair (DSBR). Recently, we showed that homologous nascent RNA can be used as a template for error-free repair of double-strand breaks (DSBs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5012f3301fa2986e889e8a678e2542b1
https://escholarship.org/uc/item/7608k70j
https://escholarship.org/uc/item/7608k70j
Autor:
Ina Yoon, Ji Ae Song, Ji Hun Suh, Sulhee Kim, Jonghyeon Son, Jong Hyun Kim, Song Yee Jang, Kwang Yeon Hwang, Myung Hee Kim, Sunghoon Kim
Publikováno v:
Molecular and cellular biology, vol 43, iss 5
Glutamyl-prolyl-tRNA synthetase 1 (EPRS1) is known to associated with fibrosis through its catalytic activity to produce prolyl-tRNA. Although its catalytic inhibitor halofuginone (HF) has been known to inhibit the TGF-β pathway as well as to reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ae605451acbd47c34efd498c573c4d
https://escholarship.org/uc/item/69t6t2hp
https://escholarship.org/uc/item/69t6t2hp
Autor:
Mohamed, Fatma F, Ge, Chunxi, Hallett, Shawn A, Bancroft, Alec C, Cowling, Randy T, Ono, Noriaki, Binrayes, Abdul-Aziz, Greenberg, Barry, Levi, Benjamin, Kaartinen, Vesa M, Franceschi, Renny T
Development of the craniofacial skeleton requires interactions between progenitor cells and the collagen-rich extracellular matrix (ECM). The mediators of these interactions are not well-defined. Mutations in the discoidin domain receptor 2 gene (DDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::d0e0f5d37db0d6b47958ef9144227d03
https://escholarship.org/uc/item/26j5f2wh
https://escholarship.org/uc/item/26j5f2wh
Autor:
Yoshihiro Ishikawa, Yuki Taga, Thibault Coste, Sara F. Tufa, Douglas R. Keene, Kazunori Mizuno, Elisabeth Tournier-Lasserve, Douglas B. Gould
Publikováno v:
The Journal of biological chemistry, vol 298, iss 12
Collagens are the most abundant proteins in the body and among the most biosynthetically complex. A molecular ensemble of over 20 endoplasmic reticulum resident proteins participates in collagen biosynthesis and contributes to heterogeneous post-tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dbeff3dfb1980b0d8730a3cad73f362
https://escholarship.org/uc/item/0gs5w663
https://escholarship.org/uc/item/0gs5w663
Autor:
Momoko Watanabe, Jessie E. Buth, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Lubayna S. Elahi, Wen Gu, Caroline A. Pearson, Arinnae Kurdian, Natella V. Baliaouri, Amanda J. Collier, Osvaldo A. Miranda, Natassia Dunn, Di Chen, Shan Sabri, Luis de la Torre-Ubieta, Amander T. Clark, Kathrin Plath, Heather R. Christofk, Harley I. Kornblum, Michael J. Gandal, Bennett G. Novitch
Publikováno v:
Stem cell reports, vol 17, iss 10
Telencephalic organoids generated from human pluripotent stem cells (hPSCs) are a promising system for studying the distinct features of the developing human brain and the underlying causes of many neurological disorders. While organoid technology is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07252158a4d10dae35565a44834d3fb7
https://escholarship.org/uc/item/66g278z4
https://escholarship.org/uc/item/66g278z4
Publikováno v:
The Journal of biological chemistry, vol 298, iss 9
In higher eukaryotes, mitochondria play multiple roles in energy production, signaling, and biosynthesis. Mitochondria possess multiple copies of mitochondrial DNA (mtDNA), which encodes 37 genes that are essential for mitochondrial and cellular func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29423ff87047b442e18909429d3540c1
https://escholarship.org/uc/item/44f7j4vb
https://escholarship.org/uc/item/44f7j4vb
Autor:
Pranidhi Sood, Athena Lin, Connie Yan, Rebecca McGillivary, Ulises Diaz, Tatyana Makushok, Ambika V Nadkarni, Sindy KY Tang, Wallace F Marshall
The giant ciliate Stentor coeruleus is a classical model system for studying regeneration and morphogenesis in a single cell. The anterior of the cell is marked by an array of cilia, known as the oral apparatus, which can be induced to shed and regen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f4307aea5242bc120efabf9de1d420
https://escholarship.org/uc/item/6wq2h5nb
https://escholarship.org/uc/item/6wq2h5nb
Activation and closed-state inactivation mechanisms of the human voltage-gated KV4 channel complexes
Publikováno v:
Molecular cell, vol 82, iss 13
The voltage-gated ion channel activity depends on both activation (transition from the resting state to the open state) and inactivation. Inactivation is a self-restraint mechanism to limit ion conduction and is as crucial to membrane excitability as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0fe105c07ee874ae8842dff939cd79
https://escholarship.org/uc/item/0tj7f6hp
https://escholarship.org/uc/item/0tj7f6hp
Autor:
R. Michael Roberts, Toshihiko Ezashi, Jasmine Temple, Joseph R. Owen, Francesca Soncin, Mana M. Parast
Publikováno v:
Cellular and molecular life sciences : CMLS, vol 79, iss 8
Cell Mol Life Sci
Cell Mol Life Sci
The Bone Morphogenetic Protein (BMP) signaling pathway has established roles in early embryonic morphogenesis, particularly in the epiblast. More recently, however, it has also been implicated in development of extraembryonic lineages, including trop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc12644b73a9e5a3c7d669396ca1bc5
https://escholarship.org/uc/item/7rm3x068
https://escholarship.org/uc/item/7rm3x068
Autor:
Francesca Soncin, Robert Morey, Tony Bui, Daniela F. Requena, Virginia Chu Cheung, Sampada Kallol, Ryan Kittle, Madeline G. Jackson, Omar Farah, Jennifer Chousal, Morgan Meads, Donald Pizzo, Mariko Horii, Kathleen M. Fisch, Mana M. Parast
Publikováno v:
Stem cell reports, vol 17, iss 6
Trophoblast stem cells (TSCs) have recently been derived from human embryos and early-first-trimester placenta; however, aside from ethical challenges, the unknown disease potential of these cells limits their scientific utility. We have previously e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eee5d799f74229d139f6e2af17d5133
https://escholarship.org/uc/item/3112255s
https://escholarship.org/uc/item/3112255s