Zobrazeno 1 - 10
of 91
pro vyhledávání: ''
Autor:
Momoko Watanabe, Jessie E. Buth, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Lubayna S. Elahi, Wen Gu, Caroline A. Pearson, Arinnae Kurdian, Natella V. Baliaouri, Amanda J. Collier, Osvaldo A. Miranda, Natassia Dunn, Di Chen, Shan Sabri, Luis de la Torre-Ubieta, Amander T. Clark, Kathrin Plath, Heather R. Christofk, Harley I. Kornblum, Michael J. Gandal, Bennett G. Novitch
Publikováno v:
Stem cell reports, vol 17, iss 10
Telencephalic organoids generated from human pluripotent stem cells (hPSCs) are a promising system for studying the distinct features of the developing human brain and the underlying causes of many neurological disorders. While organoid technology is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07252158a4d10dae35565a44834d3fb7
https://escholarship.org/uc/item/66g278z4
https://escholarship.org/uc/item/66g278z4
Autor:
Pranidhi Sood, Athena Lin, Connie Yan, Rebecca McGillivary, Ulises Diaz, Tatyana Makushok, Ambika V Nadkarni, Sindy KY Tang, Wallace F Marshall
The giant ciliate Stentor coeruleus is a classical model system for studying regeneration and morphogenesis in a single cell. The anterior of the cell is marked by an array of cilia, known as the oral apparatus, which can be induced to shed and regen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f4307aea5242bc120efabf9de1d420
https://escholarship.org/uc/item/6wq2h5nb
https://escholarship.org/uc/item/6wq2h5nb
Autor:
R. Michael Roberts, Toshihiko Ezashi, Jasmine Temple, Joseph R. Owen, Francesca Soncin, Mana M. Parast
Publikováno v:
Cellular and molecular life sciences : CMLS, vol 79, iss 8
Cell Mol Life Sci
Cell Mol Life Sci
The Bone Morphogenetic Protein (BMP) signaling pathway has established roles in early embryonic morphogenesis, particularly in the epiblast. More recently, however, it has also been implicated in development of extraembryonic lineages, including trop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc12644b73a9e5a3c7d669396ca1bc5
https://escholarship.org/uc/item/7rm3x068
https://escholarship.org/uc/item/7rm3x068
Autor:
Francesca Soncin, Robert Morey, Tony Bui, Daniela F. Requena, Virginia Chu Cheung, Sampada Kallol, Ryan Kittle, Madeline G. Jackson, Omar Farah, Jennifer Chousal, Morgan Meads, Donald Pizzo, Mariko Horii, Kathleen M. Fisch, Mana M. Parast
Publikováno v:
Stem cell reports, vol 17, iss 6
Trophoblast stem cells (TSCs) have recently been derived from human embryos and early-first-trimester placenta; however, aside from ethical challenges, the unknown disease potential of these cells limits their scientific utility. We have previously e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eee5d799f74229d139f6e2af17d5133
https://escholarship.org/uc/item/3112255s
https://escholarship.org/uc/item/3112255s
Autor:
Samhita Jain, Maximilian Haeussler, Tao Li, Keith B. Hengen, Tomasz J. Nowakowski, David Shin, Richard R. Ransohoff, Kelsey M. Hennick, Shalin B. Mehta, Christopher S. McGinnis, Matthew L. Speir, Zev J. Gartner, Matthew G. Keefe, Chang N. Kim, Sarah S. Soliman, Bryant B. Chhun, Dario Tejera, Xianhua Piao, Galina Popova
Publikováno v:
Cell stem cell, vol 28, iss 12
Microglia are resident macrophages in the brain that emerge in early development and respond to the local environment by altering their molecular and phenotypic states. Fundamental questions about microglia diversity and function during development r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07501263c562907d27e7385a92f3f463
https://escholarship.org/uc/item/1xh229wx
https://escholarship.org/uc/item/1xh229wx
Autor:
Jianqin Niu, Feng Mei, Stephen P.J. Fancy, Jonah R. Chan, Yuxin Wang, Xiaorui Wang, Lan Xiao, Guangdan Yu, Wenlong Xia, Kimberly K. Hoi
Publikováno v:
Neuron, vol 109, iss 19
Neuron
Neuron
Oligodendrocyte (OL) maturation arrest in human white matter injury contributes significantly to the failure of endogenous remyelination in multiple sclerosis (MS) and newborn brain injuries such as hypoxic ischemic encephalopathy (HIE) that cause ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcda9c045c5e743d6b62f22d0884c57e
https://escholarship.org/uc/item/9vb4k2nx
https://escholarship.org/uc/item/9vb4k2nx
Autor:
Steve Horvath, Simon T. Schafer, Dylan A. Reid, Ake T. Lu, Fred H. Gage, Christopher K. Glass, Patrick J. Reed, Grace Chou, Claire A. McClain, Jeffrey R. Jones, Jesse R. Dixon, Sahaana Chandran, Addison J. Lana, Anthony S. Ricciardulli, Enoch C. Tsui, Ioana I. Nitulescu, Tzu-Wen Wang, Jean H. Ooi, Shong Lau, Johannes C. M. Schlachetzki, Nasun Hah, Sara B. Linker
Publikováno v:
Science (New York, N.Y.), vol 372, iss 6537
Science
Science
DNA repair within neurons Humans have only a limited capacity to generate new neurons. These cells thus need to repair errors in the genome. To better understand this process, Reid et al. developed Repair-seq, a method to locate DNA repair within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d60dd82faff91dff991ec21a36ff828
https://escholarship.org/uc/item/5px9q677
https://escholarship.org/uc/item/5px9q677
Publikováno v:
Stem cell reports, vol 16, iss 3
Stem Cell Reports
Stem Cell Reports
COVID-19 is a transmissible respiratory disease caused by a novel coronavirus, SARS-CoV-2, and has become a global health emergency. There is an urgent need for robust and practical in vitro model systems to investigate viral pathogenesis. Here, we g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a830e29ea5667be8e859ed7b72d8370
https://escholarship.org/uc/item/6fh9c4d8
https://escholarship.org/uc/item/6fh9c4d8
Autor:
Julie B. Sneddon, Stacey M. Frumm, Shengyang Kevin Yu, Katharine Lee, Sonia M. Scaria, Lauren Byrnes, Joseph Chang, Aaron D. Tward, Jordan Artichoker
Publikováno v:
Cell stem cell, vol 28, iss 2
Cell Stem Cell
Cell Stem Cell
The tympanic membrane (TM) is critical for hearing and requires continuous clearing of cellular debris, but little is known about homeostatic mechanisms in the TM epidermis. Using single-cell RNA sequencing, lineage tracing, whole-organ explant, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672048c4b4cd9746822d7d4296a98566
https://escholarship.org/uc/item/22b599rv
https://escholarship.org/uc/item/22b599rv
Autor:
Thang L. Nguyen, Sixto Marcos, Pei-Yu Chiou, Shahrooz Rabizadeh, Alexander N. Patananan, Adam Lazar, Jon T. Van Lew, Noe Rodriguez, Luis Cisneros, Peter A. Sieling, Daniel Braas, Fasih M. Ahsan, Charles J. Vaske, Michael A. Teitell, Amy R. Vandiver, Amanda J. Collier, Artin Mehrabi, Alexander J. Sercel, Stephanie A.L. Kennedy, Lise Zakin, Emma R. Dawson, Tadros Wael, Alejandro Torres, Kayvan Niazi, Ting-Hsiang Wu, Justin Golovato, Kathrin Plath
Publikováno v:
Cell reports, vol 33, iss 13
Cell reports
Cell reports
SUMMARY Generating mammalian cells with desired mitochondrial DNA (mtDNA) sequences is enabling for studies of mitochondria, disease modeling, and potential regenerative therapies. MitoPunch, a high-throughput mitochondrial transfer device, produces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be74657fb561a48381afb40523ea40b
https://escholarship.org/uc/item/9xs7544n
https://escholarship.org/uc/item/9xs7544n