Zobrazeno 1 - 10
of 87
pro vyhledávání: ''
Autor:
W. James Gauderman, Ivo S. Muskens, Adam J. de Smith, Lucy A. Godley, Qianxi Feng, Eric Nickels, Andrew D. Leavitt, Thomas M. Mack, Amy C. Yee, Joseph L. Wiemels, Charité Ricker
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
BackgroundThe role of race/ethnicity in genetic predisposition of early-onset cancers can be estimated by comparing family-based cancer concordance rates among ethnic groups.MethodsWe used linked California health registries to evaluate the relative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34007ea5a017250bee9e309c2927ed9
https://escholarship.org/uc/item/1r31w3fk
https://escholarship.org/uc/item/1r31w3fk
Publikováno v:
International journal of molecular sciences, vol 22, iss 11
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5886, p 5886 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5886, p 5886 (2021)
Fifty-five to two hundred CGG repeats (called a premutation, or PM) in the 5′-UTR of the FMR1 gene are generally unstable, often expanding to a full mutation (>
200) in one generation through maternal inheritance, leading to fragile X syndro
200) in one generation through maternal inheritance, leading to fragile X syndro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296305826e97989ef18a208c4ffea6a0
https://escholarship.org/uc/item/0ns3f772
https://escholarship.org/uc/item/0ns3f772
Autor:
Jasmina S. Redzic, Larry J. Dumont, Angelo D'Alessandro, Travis Nemkov, Yang Xia, Kirk C. Hansen, Anren Song, Aarash Bordbar, Michael P. Busch, Recipient Epidemiology, Elan Z. Eisenmesser, James C. Zimring, Davide Stefanoni, Ariel Hay, Bernhard O. Palsson, Aaron Issaian, Steve Kleinman
Publikováno v:
JCI insight, vol 6, iss 3
JCI Insight
JCI Insight, Vol 6, Iss 3 (2021)
JCI Insight
JCI Insight, Vol 6, Iss 3 (2021)
Computational models based on recent maps of the red blood cell proteome suggest that mature erythrocytes may harbor targets for common drugs. This prediction is relevant to red blood cell storage in the blood bank, in which the impact of small molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d1860d195b8c1b32de04060856a431
https://escholarship.org/uc/item/7d8467k2
https://escholarship.org/uc/item/7d8467k2
Autor:
Noor Khalid, Razelle Kurzrock, Jacob J. Adashek, Suzanna Lee, Shumei Kato, Jason K. Sicklick, Van Thomas Nguyen, Ryosuke Okamura
Publikováno v:
JCI insight, vol 6, iss 1
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
BACKGROUND Although CDK4/6 inhibitors are an established treatment for hormone receptor–positive, HER2-negative metastatic breast cancers, their benefit in other malignancies remains limited.METHODS We investigated factors associated with clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66de530f4ac6efbc82971e89d868547b
https://escholarship.org/uc/item/66p2z8d2
https://escholarship.org/uc/item/66p2z8d2
Autor:
Ira T. Lott, Benjamin Tycko, Juan Fortea, Benjamin L. Handen, Nicole Schupf, Shahid Zaman, Melissa E. Petersen, Fan Zhang, Mei-Cheng Wang, H. Diana Rosas, Elizabeth Head, Michael S. Rafii, Florence Lai, James Hall, Mark Mapstone, Joseph H. Lee, Sid E. O'Bryant, Beau M. Ances, Sharon J. Krinsky-McHale, William E. Klunk, Sigan L. Hartley, Tatiana Foroud, David Julovich, Brad T. Christian, Wayne Silverman
Publikováno v:
Journal of Alzheimer's disease : JAD, vol 79, iss 2
J Alzheimers Dis
JOURNAL OF ALZHEIMERS DISEASE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Fundacion Sancho el Sabio Fundazioa (FSS)
J Alzheimers Dis
JOURNAL OF ALZHEIMERS DISEASE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Fundacion Sancho el Sabio Fundazioa (FSS)
BackgroundThe need for diagnostic biomarkers of cognitive decline is particularly important among aging adults with Down syndrome (DS). Growing empirical support has identified the utility of plasma derived biomarkers among neurotypical adults with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece812cd66a619d971c8dfee56d29083
https://escholarship.org/uc/item/6wb905q1
https://escholarship.org/uc/item/6wb905q1
Autor:
Richard B. Lanman, Lindsey M. Charo, Ryosuke Okamura, Mina Nikanjam, Razelle Kurzrock, Michael T. McHale, David Piccioni, Ramez N. Eskander, Shumei Kato, Sandip Pravin Patel
Publikováno v:
Molecular Oncology, vol 15, iss 1
Molecular Oncology, Vol 15, Iss 1, Pp 67-79 (2021)
Molecular Oncology
Molecular oncology, vol 15, iss 1
Molecular Oncology, Vol 15, Iss 1, Pp 67-79 (2021)
Molecular Oncology
Molecular oncology, vol 15, iss 1
In gynecologic cancer patients, therapy matched to ctDNA alterations (N = 33 patients) was independently associated with improved overall survival (hazard ratio: 0.34, P = 0.007) compared to unmatched therapy (N = 28 patients) in multivariate analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198ccd3cf62111be8d648264dae3a8a2
https://escholarship.org/uc/item/7tm9c0d3
https://escholarship.org/uc/item/7tm9c0d3
Autor:
Jonathan A. Bernstein, Julia M. Schaepe, Themasap Khan, Yishan Sun, Anna K. Krawisz, Judith L. Rapoport, Neal D. Amin, Masayuki Yazawa, Yuan Tian, Min-Yin Li, Carrie E. Bearden, Matthew H. Porteus, Seiji Nishino, Ruth O'Hara, Aaron Gordon, Sergiu P. Paşca, John R. Huguenard, Ricardo E. Dolmetsch, Omer Revah, Leila Kushan, Noriaki Sakai, Daniel H. Geschwind, Se-Jin Yoon, Chul Hoon Kim, Joachim Hallmayer, Carleton Goold, Kazuya Ikeda
Publikováno v:
Nature medicine, vol 26, iss 12
Nat Med
Nat Med
22q11.2 deletion syndrome (22q11DS) is a highly penetrant and common genetic cause of neuropsychiatric disease. Here we generated induced pluripotent stem cells from 15 individuals with 22q11DS and 15 control individuals and differentiated them into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdbc3b1fcaaf3737a78f5f040438e5b
https://escholarship.org/uc/item/9dn604d3
https://escholarship.org/uc/item/9dn604d3
Autor:
Junmin Wu, Po-Jui Huang, Johnathon N. Lakins, Valerie M. Weaver, Jason J. Northey, Quanming Shi, Kirk C. Hansen, Mary-Kate Hayward, Irene Acerbi, Rita A. Mukhtar, Ivory Dean, Jan Liphardt, John A. Shepherd, Alexander S. Barrett, Janna K. Mouw, Susan Samson, Stephanie Talamantes, Laurie E. Littlepage, Yunn-Yi Chen, E. Shelley Hwang, Suzanne M. Ponik, Patricia J. Keely
Publikováno v:
The Journal of clinical investigation, vol 130, iss 11
J Clin Invest
J Clin Invest
Women with dense breasts have an increased lifetime risk of malignancy that has been attributed to a higher epithelial density. Quantitative proteomics, collagen analysis, and mechanical measurements in normal tissue revealed that stroma in the high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cb2d258f41d9863c029bfabb81cd38
https://escholarship.org/uc/item/4c20x9bw
https://escholarship.org/uc/item/4c20x9bw
Autor:
Joanna A Warren, Shuntai Zhou, Yinyan Xu, Matthew J Moeser, Daniel R MacMillan, Olivia Council, Jennifer Kirchherr, Julia M Sung, Nadia R Roan, Adaora A Adimora, Sarah Joseph, JoAnn D Kuruc, Cynthia L Gay, David M Margolis, Nancie Archin, Zabrina L Brumme, Ronald Swanstrom, Nilu Goonetilleke
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
HIV-1-specific CD8+ T cells are an important component of HIV-1 curative strategies. Viral variants in the HIV-1 reservoir may limit the capacity of T cells to detect and clear virus-infected cells. We investigated the patterns of T cell escape varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fada2ce22906b34d8ac867d6e35e9dc6
https://escholarship.org/uc/item/7802w7h9
https://escholarship.org/uc/item/7802w7h9
Autor:
Jody Corey-Bloom, Douglas A. Granger, Steven W. Granger, Aeri Kim, Georgia M. Parkin, Elizabeth A. Thomas, Chase Snell, Ryan S. Fischer
Publikováno v:
International journal of molecular sciences, vol 21, iss 17
International Journal of Molecular Sciences, Vol 21, Iss 6363, p 6363 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6363, p 6363 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 17
Growing evidence suggests that inflammatory responses, in both the brain and peripheral tissues, contribute to disease pathology in Huntington&rsquo
s disease (HD), an inherited, progressive neurodegenerative disorder typically affecting adults
s disease (HD), an inherited, progressive neurodegenerative disorder typically affecting adults
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4af9416417260360c987316c36321e
https://escholarship.org/uc/item/2q8585wj
https://escholarship.org/uc/item/2q8585wj