Zobrazeno 1 - 8
of 8
pro vyhledávání: ''
Publikováno v:
Environmental Health Perspectives
When Jurkat human T cells were incubated with 20 microM of pentachlorophenol (PCP) or its metabolite, tetrachlorohydroquinone (TCHQ), for 10 hr, flow cytometric analyses revealed marked increase in the number of apoptotic cells. DNA fragmentation was
Autor:
Fuhua H. Guo, Serpil C. Erzurum
Publikováno v:
Environmental Health Perspectives
Nitric oxide is an important mediator of inflammatory responses in the lung and a key regulator of pulmonary vascular and bronchomotor tone. We have shown that the inducible nitric oxide synthase (iNOS) isoform is continuously expressed in human airw
Publikováno v:
Environmental Health Perspectives
The inflammatory response is a key component of host defense. However, excessive or persistent inflammation can contribute to the pathogenesis of disease. Inflammation is regulated, in part, by cytokines, which are small, typically glycosylated prote
Publikováno v:
Scopus-Elsevier
Environmental Health Perspectives
Environmental Health Perspectives
Epidemiological evidence suggests that cadmium (Cd) exposure causes pulmonary damage such as emphysema and lung cancer. However, relatively little is known about the mechanisms involved in Cd pulmonary toxicity. In the present study, the effects of C
Publikováno v:
Environmental Health Perspectives
The role of cell-specific metabolism in benzene toxicity was examined in both murine and human bone marrow. Hemopoietic progenitor cells and stromal cells are important control points for regulation of hemopoiesis. We show that the selective toxicity
Publikováno v:
Environmental Health Perspectives
This review article discusses a novel nontraditional site of estrogen synthesis and the potential targets of estrogen action within the male reproductive system. Our laboratories have recently demonstrated that developing spermatids in several specie
Autor:
A. Wagner, Wilfried Bursch, Rolf Schulte-Hermann, Franziska Oberhammer, Randy Jirtle, Bettina Kraupp-Grasl
Publikováno v:
Environmental Health Perspectives
The growth rate of tissues including tumors is determined by the difference between cell replication and cell death. Among different types of cell death, apoptosis, a form of programmed cell death, is of particular importance. Nongenotoxic carcinogen
Autor:
S D Douglas
Publikováno v:
Environmental Health Perspectives
For a number of years we have been working with monocytes and macrophages, and I would like to direct my remarks to a number of questions concerning the properties of the monocyte and the macrophage. I think it is quite evident that the mononuclear p