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Publikováno v:
Zhang, Lei; Radtke, Kelly; Zheng, Likun; Cai, Anna Q.; Schilling, Thomas F.; & Nie, Qing. (2012). Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain. Molecular Systems Biology, 8, 613. doi: 10.1038/msb.2012.45. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3mv418m9
Molecular Systems Biology
Molecular Systems Biology
Fluctuations in morphogens often lead to gene expression domains with rough boundaries during development. A mechanism is described whereby intracellular noise can help coordinate cellular decisions during patterning and thereby sharpen expression bo