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Autor:
Kenji Iwai, Mitsuhiro Yokoyama, Yoko Kojima, Yoshiyuki Rikitake, Tetsuaki Hirase, Seinosuke Kawashima, Nobutaka Inoue, Ken-ichi Hirata, Shigeto Takeuchi, Tatsuro Ishida
Publikováno v:
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 316(3):628-635
B-cell translocation gene 1 (BTG1) is a member of the anti-proliferative gene family that regulates cell growth and differentiation. To clarify the role of BTG1 in angiogenesis, we examined the regulation of BTG1 expression in cultured endothelial ce
Autor:
Dmitri V. Krysko, Peter Vandenabeele, Dominika Nowis, Patrizia Agostinis, Abhishek D. Garg, Jakub Golab
Immunogenic profile of certain cancer cell death mechanisms has been transmuted by research published over a period of last few years and this change has been so drastic that a new (sub)class of apoptotic cancer cell death, redefined as 'immunogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506ac053e7b101dd5b8e13d51fb29618
https://lirias.kuleuven.be/handle/123456789/632508
https://lirias.kuleuven.be/handle/123456789/632508
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (1):31-38
The study investigated the role of protein kinase C (PKC) in the modulation of agonist-induced Ca2+-dependent anion secretion by pancreatic duct cells. The short-circuit current (ISC) technique was used to examine the effect of PKC activation and inh
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. :221-231
Anionic amphiphiles such as sodium- and lithium dodecyl sulfate (SDS, LDS), or arachidonate (AA) initiate NADPH oxidase and proton channel activation in cell-free systems and intact neutrophils. To investigate whether these amphiphiles exert alloster
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (1):1-14
Advances in structure determination of membrane proteins enable analysis of the propensities of amino acids in extramembrane versus transmembrane locations to be performed on the basis of structure rather than of sequence and predicted topology. Usin
Autor:
Zhirong Zhan, Thomas Horn, Andrea Abati, Paul R. Hansen, Patricia Fetsch, Ulla Jensen, Susan E. Bates, Kuang-Ming Covitz, Thomas Litman, Torben Skovsgaard, Alastair Hansen
Publikováno v:
Litman, T, Jensen, U, Hansen, A, Covitz, K-M, Zhan, Z, Fetsch, P, Abati, A, Hansen, P R, Horn, T, Skovsgaard, T & Bates, S E 2002, ' Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2 ', BBA General Subjects, vol. 1565, no. 1, pp. 6-16 .
University of Copenhagen
University of Copenhagen
Recent studies have characterized the ABC half-transporter associated with mitoxantrone resistance in human cancer cell lines. Encoded by the ABCG2 gene, overexpression confers resistance to camptothecins, as well as to mitoxantrone. We developed fou
Autor:
Wolfram S. Kunz
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. (1):12-19
The classical concept of ATP-demand control of energy metabolism in skeletal muscle has to be modified on the basis of studies showing the influence of additional controlling parameters (reducing equivalent supply, oxygen availability, proton leak, d
Autor:
Mark S.P. Sansom, Frank S. Cordes, Isaiah T. Arkin, Andreas Kukol, Lucy R. Forrest, Wolfgang B. Fischer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (2):291-298
Vpu is an 81 amino acid auxiliary protein in HIV-1 which exhibits channel activity. We used two homo-pentameric bundles with the helical transmembrane segments derived from FTIR spectroscopy in combination with a global molecular dynamics search prot
Autor:
Philippe Gros, Jie Cai
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (1):63-76
The ATP-binding cassette (ABC) transporter superfamily is a large gene family that has been highly conserved throughout evolution. The physiological importance of these membrane transporters is highlighted by the large variety of substrates they tran
Autor:
Ken Iseki, Mitsuru Sugawara, Katsumi Miyazaki, Michiya Kobayashi, Kasumi Sakai, Megumi Kurosawa
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (1):149-155
The effects of transmembrane electric potential difference and ionic strength on the permeation of tryptamine and indoleacetic acid across a Caco-2 cell monolayer were examined. A decrease in the transmembrane electric potential difference caused by