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pro vyhledávání: '"David J. Maloney"'
Autor:
David J. Maloney, Elisabeth D. Martinez, Anton Simeonov, Ganesha Rai, John Santoyo, Lingling Duan, Carlos M. Roggero, Jer Tsong Hsieh, Ajit Jadhav, Qing Jun Zhang, Shihong Ma, Guanghua Xiao, Ganesh V. Raj, Zhi Ping Liu, Qun Wei, Yunyun Zhou, Josep Rizo
Publikováno v:
Chemistry & Biology. (9):1185-1196
Summary Histone lysine demethylase KDM4/JMJD2s are overexpressed in many human tumors including prostate cancer (PCa). KDM4s are co-activators of androgen receptor (AR) and are thus potential therapeutic targets. Yet to date few KDM4 inhibitors that