Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Louis M. Staudt"'
Ribosomal Protein S3: A KH Domain Subunit in NF-κB Complexes that Mediates Selective Gene Regulation
Autor:
Michael J. Lenardo, Fengyi Wan, David Levens, Lixin Zheng, Nicolas Bidère, Vijay Hegde, Andrew L. Snow, Louis M. Staudt, D. Eric Anderson, Lloyd T. Lam, Robert A. Barnitz, Walter A. Deutsch
Publikováno v:
Cell. (5):927-939
NF-kappaB is a DNA-binding protein complex that transduces a variety of activating signals from the cytoplasm to specific sets of target genes. To understand the preferential recruitment of NF-kappaB to specific gene regulatory sites, we used NF-kapp
Autor:
Rushad Pavri, Qiao Wang, Geng Liu, Michel C. Nussenzweig, Bin Song, Steevenson Nelson, Zhonghui Tang, Rafael Casellas, Jason Qian, Cornelis Murre, Louis M. Staudt, Longyun Chen, Laura Vian, Wendy Dubois, Ofir Hakim, Marei Dose, Qiang Pan-Hammarström, Thiago Y. Oliveira, Parirokh Awasthi, Anna Gazumyan, Christopher Benner, Ewy Mathé, Mila Jankovic, Shida Zhu, Wolfgang Resch, Kyong-Rim Kieffer-Kwon, Genqing Liang, Lionel Feigenbaum, Nathanael Pruett, Davide F. Robbiani, Yijun Ruan
Publikováno v:
Cell
Summary The antibody gene mutator activation-induced cytidine deaminase (AID) promiscuously damages oncogenes, leading to chromosomal translocations and tumorigenesis. Why nonimmunoglobulin loci are susceptible to AID activity is unknown. Here, we st