Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David L. Huso"'
Publikováno v:
Virology. (1):86-92
Suitable animal models are needed to study monkeypox virus (MPXV) as human monkeypox clinically resembles smallpox and MPXV is a zoonotic and potential bioterroristic agent. We have demonstrated that a species of African dormice, Graphiurus kelleni,
Autor:
David L. Huso, Yardena Samuels, Laura DeLong, Christoph Lengauer, Carlo Rago, Luis A. Diaz, Ian Cheong, Bert Vogelstein, Victor E. Velculescu, Oleg Schmidt-Kittler, Jordan M. Cummins, Kenneth W. Kinzler
Publikováno v:
Cancer Cell. (6):561-573
SummaryPIK3CA is mutated in diverse human cancers, but the functional effects of these mutations have not been defined. To evaluate the consequences of PIK3CA alterations, the two most common mutations were inactivated by gene targeting in colorectal
Autor:
Li Li, Diane Heiser, Michael I. Collector, Ian M. Kaplan, Curt I. Civin, David L. Huso, S. Haihua Chu, Saul J. Sharkis, Donald Small
Publikováno v:
Cell Stem Cell. (3):346-358
Internal tandem duplication (ITD) mutations within the FMS-Like Tyrosine Kinase gene (FLT3) render the receptor constitutively active, driving proliferation and survival in leukemic blasts. Expression of Flt3-ITD from the endogenous promoter in a mur