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pro vyhledávání: '"Tuan Anh Phu"'
Publikováno v:
Mol Ther
Molecular therapy : the journal of the American Society of Gene Therapy, vol 30, iss 6
Molecular therapy : the journal of the American Society of Gene Therapy, vol 30, iss 6
Cardiometabolic disease is an increasing cause of morbidity and death in society. While M1-like macrophages contribute to metabolic inflammation and insulin resistance, those polarized to an M2-like phenotype exert protective properties. Building on
Autor:
Hiromitsu Nakauchi, Tuan Anh Phu, Laura Bouchareychas, Phat Duong, Bessie Meechoovet, Warren J. Gasper, Kendall Van Keuren-Jensen, Eric Alsop, Martin Ng, Ryo Yamamoto, Robert L. Raffai, Rebecca Reiman
Publikováno v:
iScience
iScience, Vol 24, Iss 8, Pp 102847-(2021)
iScience, Vol 24, Iss 8, Pp 102847-(2021)
Summary We investigated whether extracellular vesicles (EVs) produced under hyperglycemic conditions could communicate signaling to drive atherosclerosis. We did so by treating Apoe−/− mice with exosomes produced by bone marrow-derived macrophage