Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Susan V. Hughes"'
Autor:
Paul Cockwell, Neil T. Raymond, Susan V. Hughes, Alexander J. Howie, Daniel Zehnder, Julia Lepenies, Paul M. Stewart, Marcus Quinkler, Rosemary Bland, Kevin S. Eardley, Martin Hewison
Publikováno v:
Kidney International. 74:1343-1353
To examine any potential role for 1,25-dihydroxyvitamin D (1,25(OH)2D) in inflammation associated with chronic kidney disease we measured vitamin D metabolites, markers of inflammation and gene expression in 174 patients with a variety of kidney dise
Autor:
Susan V. Hughes, Martin Hewison, Rosemary Bland, Susan L.F. Chan, Paul E. Squires, Claire E. Hills, Danijela Markovic
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. :121-125
A number of studies have suggested that Vitamin D has a potential role in the development/treatment of diabetes. These effects may be mediated by circulating levels of 1alpha,25(OH)(2)D(3), but local production of 1alpha,25(OH)(2)D(3), catalysed by t
Publikováno v:
Molecular and Cellular Endocrinology. 142:131-139
To characterize further the function of the intracellular vitamin D receptor (VDR), we have developed stable transfectant variants of a vitamin D-responsive cell line (U937) which express either decreased or increased numbers of VDR. In this study we