Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robert F. Paulson"'
Publikováno v:
Exp Hematol
Steady-state erythropoiesis generates new erythrocytes at a constant rate, and it has enormous productive capacity. This production is balanced by the removal of senescent erythrocytes by macrophages in the spleen and liver. Erythroid homeostasis is
Publikováno v:
Experimental Hematology. 88:S75
Inflammation caused by infection or tissue damage has a profound effect on hematopoiesis. Pro-inflammatory cytokines skew hematopoiesis to increase the production of myeloid effector cells, but this change comes with a cost as erythropoiesis is inhib
Publikováno v:
Exp Hematol
In contrast to steady-state erythropoiesis, which generates new erythrocytes at a constant rate, stress erythropoiesis rapidly produces a large bolus of new erythrocytes in response to anemic stress. In this study, we illustrate that Yes-associated p
Autor:
Chen Wang, Lucy R. Osborne, Monica L. Bailey, Robert F. Paulson, William L. Stanford, Ann M. Flenniken, Mark D. Minden, Nicole M. Anderson, Kelly M. McNagny, Janet Rossant, Elizabeth S. L. Berndl, Zorana Berberovic, Dwayne L. Barber, S. Lee Adamson
Publikováno v:
Experimental Hematology. 40:48-60
The ability of random mutagenesis techniques to annotate the mammalian genome can be hampered due to genetic redundancy and compensatory pathways that mask heterozygous mutations under homeostatic conditions. The objective of this study was to devise
Autor:
Jin-Soo Kim, Prithvia Devadas, Joshua J. Coon, Emery H. Bresnick, Skye C. McIver, Robert F. Paulson, Erik A. Ranheim, Alexander S. Hebert, Colin N. Dewey, Sunduz Keles, Kirby D. Johnson, Daniel R. Matson, Irene M. Ong, Xin Gao, Kyle J. Hewitt, Charu Mehta, Koichi R. Katsumura
Publikováno v:
Experimental Hematology. 53:S28
Publikováno v:
Experimental Hematology. 53:S72
Publikováno v:
Experimental Hematology. 37:549-558
Objective In mice, homeostatic erythropoiesis occurs primarily in the bone marrow. However, in response to acute anemia, bone morphogenetic proteins 4 (BMP-4)−dependent stress erythropoiesis occurs in the adult spleen. BMP-4 can also regulate stres
Publikováno v:
Experimental Hematology. 37:10-18
Objective Podocalyxin expression on Ter119 + erythroblasts is induced following administration of erythropoietin (Epo) or phenylhydrazine treatment, but is notably absent on committed erythroid progenitors during homeostatic red cell turnover. Follow
Autor:
Margherita T. Cantorna, Monica Froicu, Omid F. Harandi, Veronika Weaver, Andrew C. Chang, Anja Wittke, Robert F. Paulson, Avery August
Publikováno v:
Archives of Biochemistry and Biophysics. 460:306-313
Mice lacking the vitamin D receptor (VDR) are resistant to airway inflammation. Pathogenic immune cells capable of transferring experimental airway inflammation to wildtype (WT) mice are present and primed in the VDR KO mice. Furthermore, the VDR KO
Autor:
Laura Bennett, Robert F. Paulson
Publikováno v:
Experimental Hematology. 44:S58