Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Prasada Rao S. Kodavanti"'
Autor:
Andres R, Henriquez, Samantha J, Snow, Thomas W, Jackson, John S, House, Devin I, Alewel, Mette C, Schladweiler, Matthew C, Valdez, Danielle L, Freeborn, Colette N, Miller, Rachel, Grindstaff, Prasada Rao S, Kodavanti, Urmila P, Kodavanti
Publikováno v:
Toxicology and Applied Pharmacology. 457:116295
Psychosocially-stressed individuals might have exacerbated responses to air pollution exposure. Acute ozone exposure activates the neuroendocrine stress response leading to systemic metabolic and lung inflammatory changes. We hypothesized chronic mil
Autor:
David W. Herr, Matthew Valdez, Timothy J. Shafer, Cina M. Mack, Prasada Rao S. Kodavanti, Richard M. LoPachin, Andrew F.M. Johnstone
Publikováno v:
Toxicol In Vitro
The Hard-Soft Acid and Base hypothesis can be used to predict the potential bio-reactivity (electrophilicity) of a chemical with intracellular proteins, resulting in neurotoxicity. Twelve chemicals predicted to be neurotoxic were evaluated in vitro i
Publikováno v:
Toxicology and Applied Pharmacology. 256:290-299
The vast literature on the mode of action of polychlorinated biphenyls (PCBs) indicates that PCBs are a unique model for understanding the mechanisms of toxicity of environmental mixtures of persistent chemicals. PCBs have been shown to adversely aff
Publikováno v:
Frontiers in Neuroendocrinology. 31:479-496
Organohalogen compounds are global environmental pollutants. They are highly persistent, bioaccumulative, and cause adverse effects in humans and wildlife. Because of the widespread use of these organohalogens in household items and consumer products
Publikováno v:
Toxicology and Applied Pharmacology. 245:1-8
Polybrominated diphenyl ethers (PBDEs) are used as additive flame retardants and have been detected in human blood, adipose tissue, and breast milk. Both in vitro and in vivo studies have shown that the effects of PBDEs are similar to the known human
Publikováno v:
Toxicology and Applied Pharmacology. 236:257-260
Publikováno v:
Toxicology and Applied Pharmacology. 231:179-196
Epidemiological studies indicate that low levels of polychlorinated biphenyl (PCB) exposure can adversely affect neurocognitive development. In animal models, perturbations in calcium signaling, neurotransmitters, and thyroid hormones have been postu
Publikováno v:
Toxicology and Applied Pharmacology. 231:165-178
The developmental consequences of exposure to the polychlorinated biphenyls (PCBs) have been widely studied, making PCBs a unique model to understand issues related to environmental mixture of persistent chemicals. PCB exposure in humans adversely af
Publikováno v:
NeuroToxicology. 27:118-124
Polychlorinated biphenyls (PCBs) are prevalent in the environment despite the ban of their use for decades and offer a model system to understand developmental neurotoxicity of persistent pollutants. Disturbances in brain development and cognition ar
Publikováno v:
Molecular Brain Research. 111:123-135
PCBs have been shown to alter several neurochemical end-points and are implicated in the etiology of some neurological diseases. Recent in vivo studies from our laboratory indicated that developmental exposure to a commercial PCB mixture, Aroclor 125