Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Michael J. Pishvaian"'
Autor:
Giovanni Antico, Elisabetta Malangone-Monaco, Michael J. Pishvaian, Yunes Doleh, Ashley L. Cole, Virginia Noxon
Publikováno v:
Pancreatology. 20:1434-1441
Background Objectives: Pancreatic cancer (PC) is a costly disease with a limited life-expectancy as it generally presents as an advanced, metastatic disease. Though current literature suggests cost varies by first line treatment, there is limited rea
Autor:
Stephen P. Hack, H. Hochster, Heba Abdullah, Wendy Verret, S. Stein, Aiwu Ruth He, Kazushi Numata, J.W. Lee, Myung-Mook Lee, Baek Yeol Ryoo, Kyung Hun Lee, David P. Ryan, Edward Gane, Masanori Ikeda, A. Dev, Chih-Hung Hsu, Chiun Hsu, N. Sasahira, Jessica Spahn, Amit Mahipal, Y-J. Bang, Yee Chao, Benson M. George, Manabu Morimoto, Niall C. Tebbutt, Michael J. Pishvaian, Michael S. Lee, John H. Strickler, Stacey Stein, K. Numata, Johanna C. Bendell, Gulam Abbas Manji, Yulei Wang, Bo Liu, Aiwu R. He, Ho-Sun Chung, Shukui Qin, Samantha Davis, Jen-Shi Chen, Baek-Yeol Ryoo
Publikováno v:
The Lancet Oncology. 21:808-820
Summary Background Dual blockade of PD-L1 and VEGF has enhanced anticancer immunity through multiple mechanisms and augmented antitumour activity in multiple malignancies. We aimed to assess the efficacy and safety of atezolizumab (anti-PD-L1) alone
Autor:
Kohei Shitara, Haeseong Park, Tanios Bekaii-Saab, Sunnie S. Kim, Suneel Kamath, Michael J. Pishvaian, Christopher Chen, David B. Zhen, Joal Mayor, Qianwen Tan, John H. Strickler
Publikováno v:
Annals of Oncology. 33:S502
Autor:
Irina M. Cazacu, Sinchita Roy-Chowdhuri, Manoop S. Bhutani, Anirban Maitra, Michael J. Pishvaian
Publikováno v:
Pancreatology. 20:391-393
Pancreatic cancer patients have not benefited from survival improvements brought about by personalized medicine in other malignancies. Even though this is the era of precision medicine, unfortunately most clinicians in practice either do not embrace
Autor:
Suneel Deepak Kamath, T. S. Bekaii-Saab, Haeseong Park, James M. Ford, C. Lux, Sunnie S. Kim, Michael J. Pishvaian, John H. Strickler, D. Zhen, J.G. Mayor, Q. Tan
Publikováno v:
Annals of Oncology. 32:S1073-S1074
Autor:
Louis M. Weiner, Bedilu Allo, Michael J. Pishvaian, Sara C. Sprague, Ivana Peran, Shahin Assefnia, Stephen S. Yoo, Eveline E. Vietsch, Michael B. Atkins, Kelly A. Martin, Anton Wellstein, Andrew A. Quong, Aimy Sebastian, Nicholas R. Hum, Gabriela G. Loots, Matthew McCoy, Stephen W. Byers, Sivanesan Dakshanamurthy, Anastasia Mavropoulos
Publikováno v:
Gastroenterology
Gastroenterology, vol 160, iss 4
Gastroenterology, vol 160, iss 4
BACKGROUND & AIMS: Pancreatic ductal adenocarcinomas (PDAC) are characterized by fibrosis and an abundance of cancer-associated fibroblasts (CAFs). We investigated strategies to disrupt interactions among CAFs, the immune system, and cancer cells, fo
Autor:
Crystal S. Denlinger, Serguei Soukharev, Gabriel Robbie, Jennifer McDevitt, Haifeng Bao, Patricia C. Ryan, Song Ren, Michael J. Pishvaian, Jonathan D. Norton, Michael A. Morse
Publikováno v:
Clinical Colorectal Cancer. 15:345-351
Introduction MEDI-565, a bispecific, single-chain antibody targeting human carcinoembryonic antigen on tumor cells and the CD3 epsilon subunit of the human T-cell receptor complex, showed antitumor activity in carcinoembryonic antigen-expressing tumo
Autor:
Marc R. Matrana, Timothy V. Larson, Michael J. Pishvaian, Jordan M. Winter, John A. Glaspy, Flavio G. Rocha, Ming Zhong, Elias Kouchakji, Vincent J. Picozzi, Mairead Carney, Tom Neff, Ewa Carrier, Kabir Mody, Seth Porter
Publikováno v:
SSRN Electronic Journal.
Background: Pancreatic ductal adenocarcinomas (PDAC) exhibit a high degree of desmoplasia with extensive connective tissue growth factor (CTGF) expression and extracellular matrix production. Tumor response and potential for resection in locally adva
Autor:
Jordan Winter, Ewa Carrier, Marc R. Matrana, Mairead Carney, Kabir Mody, Seth Porter, John A. Glaspy, Adnan Alseidi, Flavio G. Rocha, Vincent J. Picozzi, Michael J. Pishvaian, Timothy V. Larson, Elias Kouchakji
Publikováno v:
ESMO Open
Purpose Pancreatic ductal adenocarcinomas exhibit a high degree of desmoplasia due to extensive extracellular matrix deposition. Encasement of mesenteric vessels by stroma in locally advanced pancreatic cancer (LAPC) prevents surgical resection. This
Autor:
Patricia DeArbeloa, Edik M. Blais, Emanuel F. Petricoin, Michael J. Pishvaian, Lynn M. Matrisian, Emily Lyons, Subha Madhavan, Jonathan R. Brody, Cassadie Moravek
Publikováno v:
Annals of Oncology. 30:vi30
The Know Your Tumor initiative identifies pancreatic cancer patients across the USA eligible for molecular testing through the Pancreatic Cancer Action Network call center. Perthera, Inc obtains patient consent, coordinates molecular testing, convene