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pro vyhledávání: '"Melisa Vance"'
Publikováno v:
Molecular Therapy. 24:S40-S41
Mucopolysaccharidosis type 1 (MPS1), also known as Hurler syndrome, is a genetic lysosomal storage disease that results from the loss-of-function mutations present on the L-iduronidase (IDUA) gene. As a consequence, glycosaminoglycans accumulate aber
Publikováno v:
Molecular Therapy. 24:S217-S218
AAV gene therapy has demonstrated success for the treatment of several ocular diseases with the tropism and efficiency of AAV retinal transduction being a function of the route of administration. Subretinal injection has been the primary route to del
Autor:
Melisa Vance, Joana S. Boura, Christopher D. Porada, Cláudia Lobato da Silva, Graça Almeida-Porada, Catarina Madeira, Weihong Yin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Mesenchymal stromal cells (MSC) constitutively express low levels of human leukocyte antigen-G (HLA-G), which has been shown to contribute to their immunomodulatory and anti-inflammatory properties. Here, we hypothesized that overexpression of HLA-G