Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lucia Knopfová"'
Publikováno v:
Cellular Signalling. 100:110476
Autor:
Lucia Janáčová, Jakub Faktor, Petr Beneš, Pavel Bouchal, Lucia Knopfová, Pavel Fabian, Lenka Čápková
Publikováno v:
ESMO Open. 3:A115-A116
Introduction Catechol-O-methyltransferase (COMT) plays an essential role in detoxification of catechols by transferring the methyl group from S-adenosyl-l-methionine to the substrate. In breast cancer, it catalyses methylation of oestrogen metabolite
Publikováno v:
Cellular Signalling. 25:1546-1555
Nuclear factors of activated T-cells (NFATs) are important regulators of the cytokine gene expression in activated T-cells. In the last decade, NFATs have been shown to regulate cell cycle, differentiation and apoptosis in cells of various origins re
Publikováno v:
Pathology. 46:S76
Transcription factor c-Myb is required for maintenance of progenitor cells in colon epithelium. Deregulation of c-Myb is frequently linked with tumorigenesis. For colorectal carcinomas, high c-Myb expression denotes tumors with poor prognosis. Oxidat
Publikováno v:
European Journal of Cancer Supplements. 8:194
The aim of this study was to assess the role of the c-Myb protein in control of invasivity of breast cancer cells. MDA-MB-231 breast cancer cells were transfected with the c-Myb coding cDNA to prepare MDA-MB-231MYBup derivatives. MDA-MB-231MYBup cell