Zobrazeno 71 - 80
of 192
pro vyhledávání: '"Kevin J Harrington"'
Autor:
Alan Melcher, Feorillo Galivo, Jill Thompson, Kevin J. Harrington, Steven M. Albelda, Rosa Maria Diaz, Timothy Kottke, Phonphimon Wongthida, Candice Willmon, Richard G. Vile
Publikováno v:
Molecular Therapy. 19(1):140-149
Despite having potent oncolytic activity, in vitro, direct intratumoral injection of oncolytic vesicular stomatitis virus (VSV) into established AE17ova mesothelioma tumors in C57Bl/6 mice had no therapeutic effect. During studies to combine systemic
Autor:
Guy Simpson, Kevin J. Harrington, Robin Prestwich, Nicola E. Annels, Hardev Pandha, Alan Melcher, Richard G. Vile, Lucy Heinemann
Publikováno v:
Molecular Therapy. 18(12):2085-2093
The potential for increased sensitivity of tumor cells to oncolytic reovirus by altering the normal cell cycle using clinically available pharmacological agents was investigated. B16.F10 mouse melanoma cells were partially synchronized with hydroxyur
Publikováno v:
Cryobiology. 61:268-274
Tumour cryotherapy has been described as both immunostimulatory and immunoinhibitory in previous studies. However, previous studies have not accurately reproduced the precise conditions of current clinical cryotherapy. The objective of this study is
Publikováno v:
Radiotherapy and Oncology. 97:249-257
Inverse planned Intensity modulated radiotherapy (IMRT) can minimize the dose to normal structures and therefore can reduce long-term radiotherapy-related morbidity and may improve patients' long-term quality of life. Despite overwhelming evidence th
Autor:
Kevin J. Harrington, Stan B. Kaye, Christopher M. Nutting, C. Mikropoulos, S.A. Bhide, Katie L. Newbold, Ceri Powell
Publikováno v:
Cancer Treatment Reviews. 36:566-575
Approximately two million fractions of radiotherapy are administered in the UK every year, as part of adjuvant, radical or palliative cancer treatment. For many tumour types, radiotherapy is routinely combined with concomitant chemotherapy as part of
Autor:
Sarah L. Gulliford, Katie L. Newbold, Christopher M. Nutting, Shreerang Bhide, Jack F. Fowler, Kevin J. Harrington, Nicola Rosenfelder
Publikováno v:
Radiotherapy and Oncology. 97:86-91
Purpose: This study describes the acute response of oral and pharyngeal mucosa to chemo-IMRT schedules using different doses per fraction. Materials and methods: Patients, treated in prospective trials of concomitant chemo-IMRT with 2.17 Gy, 2.25 Gy
Autor:
Shreerang Bhide, Richard G. Vile, Georges Vassaux, Kevin J. Harrington, Shane Zaidi, Christopher M. Nutting, C L White, Mohan Hingorani, Hardev Pandha, Konstantinos N. Syrigos, Alan Melcher
Publikováno v:
Molecular Therapy. 18:1599-1605
Adenoviral (AdV) transfer of sodium iodide symporter (NIS) gene has translational potential, but relatively low levels of transduction and subsequent radioisotope uptake limit the efficacy of the approach. In previous studies, we showed that combinin
Publikováno v:
Cytokine & Growth Factor Reviews
It is time for those working on oncolytic viruses to take stock of the status of the field. We now have at our disposal an array of potential therapeutic agents, and are beginning to conduct early-phase clinical trials in patients with relapsed/metas
Autor:
Cheryl Richardson, S. Brennan, Angela Riddell, Merina Ahmed, K. Burke, Mark R. Davies, Christopher M. Nutting, Christine Kong, Kevin J. Harrington, Maria A. Schmidt, Aslam Sohaib, Kate Newbold, Marianne Usher
Publikováno v:
Radiotherapy and Oncology. 94:161-167
Introduction Magnetic resonance imaging (MRI) provides superior diagnostic accuracy over computed tomography (CT) in oropharyngeal tumours. Precise delineation of the gross tumour volume (GTV) is mandatory in radiotherapy planning when a GTV boost is
Autor:
G.T. Royle, Christopher M. Nutting, V. Cosgrove, Corinne Faivre-Finn, Karen J. Kirkby, Emma Hall, M. van Herk, Kevin J. Harrington, Ranald I Mackay, David J. Hawkes, Maria A. Hawkins, Alastair Gray, Tim Maughan, F. Van den Heuvel, S. Falk, Sarah Brown, Ann Henry, Uwe Oelfke, Robert Chuter, Ricky A. Sharma, David Sebag-Montefiore
Publikováno v:
Lung Cancer. 115:S60