Zobrazeno 1 - 5
of 5
pro vyhledávání: '"John M. Higgins"'
Autor:
Andrew M. Goldsweig, Edward O'Leary, Karla Costello, Thomas R. Porter, Feng Xie, John M. Higgins, David Barton, Ping Zeng, Poonam Velagapudi, Joan Olson, Yiannis S. Chatzizisis, Arif Albulushi
Publikováno v:
Journal of the American College of Cardiology. 77:1270
Autor:
Brent Klinkhammer, John M. Higgins
Publikováno v:
Journal of the American College of Cardiology. 77:710
Publikováno v:
Biophysical Journal. 110:2751-2758
The majority of morbidity and mortality in sickle cell disease is caused by vaso-occlusion: circulatory obstruction leading to tissue ischemia and infarction. The consequences of vaso-occlusion are seen clinically throughout the vascular tree, from t
Autor:
Timothy R. Hillman, YongKeun Park, HeeSu Byun, Ramachandra R. Dasari, John M. Higgins, Zhangli Peng, Monica Diez-Silva, Ming Dao, Subra Suresh
Publikováno v:
PMC
Sickle cell disease (SCD) is characterized by the abnormal deformation of red blood cells (RBCs) in the deoxygenated condition, as their elongated shape leads to compromised circulation. The pathophysiology of SCD is influenced by both the biomechani
Publikováno v:
Transfusion Clinique et Biologique. 15:12-13
Vaso-occlusive events are responsible for the majority of morbidity and mortality in sickle cell disease. Predisposing conditions are unclear, and proximal causes have not been established. Despite decades of intense study, until recently there has n