Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hugues de Thé"'
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 17:S271-S272
Autor:
Jun Zhu, Rihab Nasr, Laurent Pérès, Florence Riaucoux-Lormière, Nicole Honoré, Caroline Berthier, Dmitrii Kamashev, Jun Zhou, Dominique Vitoux, Catherine Lavau, Hugues de Thé
Publikováno v:
Cancer Cell. 12(1):23-35
SummaryAlthough PML-enforced RARA homodimerization allows PML/RARA to bind DNA independently of its coreceptor RXR, the latter was identified within the PML/RARA complex. We demonstrate that a PML/RARA mutant defective for RXR binding fails to trigge
Autor:
Philippe Bertheau, Jacqueline Lehmann-Che, Mariana Varna, Anne Dumay, Brigitte Poirot, Raphaël Porcher, Elisabeth Turpin, Louis-François Plassa, Anne de Roquancourt, Edwige Bourstyn, Patricia de Cremoux, Anne Janin, Sylvie Giacchetti, Marc Espié, Hugues de Thé
Publikováno v:
The Breast. 22:S27-S29
Despite an obvious central role of p53 in the hallmarks of cancer, TP53 status is not yet used for the management of breast cancer. Recent findings may lead to reconsider the role of p53 in breast cancer. TP53 mutations are the most frequent genetic
Autor:
Philippe Bertheau, Louis François Plassa, Florence Lerebours, Anne de Roquancourt, Elisabeth Turpin, Rosette Lidereau, Hugues de Thé, Anne Janin
Publikováno v:
Laboratory Investigation. 81:1397-1402
Solid tumors are composed not only of tumor cells but also of stromal nonneoplastic cells. In whole tumor samples, stromal cells retaining their alleles may therefore obscure detection of loss of heterozygosity (LOH) in tumor cells. An increasing num
Autor:
Francine Puvion-Dutilleul, Mounira K. Chelbi-Alix, Marcel Koken, Frédérique Quignon, Edmond Puvion, Hugues De Thé
Publikováno v:
Experimental Cell Research. 218:9-16
We have studied at the ultrastructural level the localization of PML protein in response to adenovirus infection in HeLa cells. In nuclei of noninfected cells or at the early stage of infection, PML accumulated at the border of nuclear bodies as prev
Autor:
Guillaume Ploussard, Francis Dubosq, Hany Soliman, Jérôme Verine, François Desgrandchamps, Hugues De Thé, Pierre Mongiat-Artus
Publikováno v:
Urology. 76:513.e13-513.e18
Objective To investigate the prognostic value of loss of heterozygosity (LOH) at chromosome 9p in patients with non–muscle-invasive bladder cancer (NMI-BC). Methods Between 2000 and 2006, we included in the study 84 patients with NMI-BC. LOH analys
Autor:
Ali Saib, Martine Canivet, Marie-Louise Giron, Françis Bolgert, Joceline Valla, Sylvie Lagaye, Jorge Périès, Hugues de Thé
Publikováno v:
The Lancet. 343:666