Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Godfrey, S."'
Autor:
Yajun Geng, Aoshuang Chen, Nathan Asner, Gnanasekar Munirathinam, Sarah Bliss, Godfrey S. Getz, Priyanka D Patel, Sunil Palani, Yue Pan, Catherine A. Reardon, Subramanyam Dasari, Karin C. Nitiss, Guoxing Zheng, Hongming Shen, Hanzhong Ke, Zhaoqi Yan
Publikováno v:
Atherosclerosis. 251:31-38
Anti-HMGB1 autoimmunity plays a role in systemic lupus erythematosus (SLE). Because SLE increases atherosclerosis, we asked whether the same autoimmunity might play a role in atherogenesis.We looked for the induction of HMGB1-specific B and T cell re
Autor:
Celina Edelstein, John J. Albers, Marlys L. Koschinsky, Santica M. Marcovina, Godfrey S. Getz
Publikováno v:
Journal of Lipid Research. 59:921-922
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 202-213 (2013)
The synthesis of apoE by adipocytes has profound effects on adipose tissue lipid flux and gene expression. Using adipose tissue transplantation from wild-type (WT) to apoE knockout (EKO) mice, we show that adipose tissue also contributes to circulati
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 951-963 (2012)
Plasma HDL levels are inversely associated with atherosclerosis. Inbred mouse strains differ in plasma HDL levels and susceptibility to atherosclerosis. Atherosclerosis-susceptible C57BL/6J mice possess plasma HDL levels 2-fold lower than atheroscler
Autor:
Catherine A. Reardon, Leon M. Tai, Gregory W. Munson, Mary Jo LaDu, Lisa Jungbauer, Godfrey S. Getz, Chunjiang Yu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1821:295-302
The association between apolipoprotein E (apoE) and amyloid-β peptide (Aβ) may significantly impact the function of both proteins, thus affecting the etiology of Alzheimer’s disease (AD). However, apoE/Aβ interactions remain fundamentally define
Autor:
Godfrey S. Getz, Catherine A. Reardon
Publikováno v:
Journal of Lipid Research. 52:1861-1864
Given the increased prevalence of cardiovascular disease in the world, the search for genetic variations that impact risk factors associated with the development of this disease continues. Multiple genetic association studies demonstrate that procoll
Autor:
Carole L. Banka, Atsushi Miyanohara, Joseph L. Witztum, Andrew C. Li, Theodore Friedmann, Sotirios Tsimikas, Jennifer Pattison, Michael Torzewski, Peter X. Shaw, Esther Merki, N. Chin Lai, Catherine A. Reardon, H. Kirk Hammond, Karsten Hartvigsen, Meng-Yun Chou, Godfrey S. Getz, Janina Sollors
Publikováno v:
Journal of the American College of Cardiology. 58:1715-1727
ObjectivesWe sought to assess the in vivo importance of scavenger receptor (SR)–mediated uptake of oxidized low-density lipoprotein (OxLDL) in atherogenesis and to test the efficacy of human antibody IK17-Fab or IK17 single-chain Fv fragment (IK17-
Autor:
Pauline Byakika-Kibwika, Jasper Ogwal-Okeng, Aloysius Lubega, John R. S. Tabuti, Collins Kukunda-Byobona, Hindam Lanyero, Máirín Ryan, Paul Waako, Mohammed Lamorde, Godfrey S. Bbosa, Celestino Obua, Concepta Merry
Publikováno v:
Journal of Ethnopharmacology. 130:43-53
Introduction and objectives: In Uganda, there are over one million people with HIV/AIDS. When advanced, this disease is characterized by life-threatening opportunistic infections. As the formal health sector struggles to confront this epidemic, new m
Autor:
Jing-Tian Xie, Godfrey S. Getz, Shutsung Liao, Catherine A. Reardon, Dacheng Peng, Richard A. Hiipakka
Publikováno v:
Atherosclerosis. 208:126-133
The effects of liver X receptor (LXR) agonists on plasma lipid homeostasis, especially triglyceride metabolism are controversial. Here we examined the effect of long-term activation of LXR on plasma lipid homeostasis in wild-type C57BL/6 and LDL rece
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 9, Pp 1889-1900 (2009)
Modifying apolipoprotein (apo) A-I mimetic peptides to include a proline-punctuated alpha-helical repeat increases their anti-inflammatory properties as well as allows better mimicry of full-length apoA-I function. This study compares the following m