Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Franziska Theilig"'
Autor:
Makhabbat Saudenova, Jessica Promnitz, Gerrit Ohrenschall, Nina Himmerkus, Martina Böttner, Madlen Kunke, Markus Bleich, Franziska Theilig
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1869:119190
Cathepsin B (CatB) is a very abundant lysosomal protease with endo- and carboxydipeptidase activities and even ligase features. In this review, we will provide a general characterization of CatB and describe structure, structure-derived properties an
Publikováno v:
Kidney international
Severe sepsis is often accompanied by acute renal failure with renal tubular dysfunction. Albuminuria is a common finding in septic patients and we studied whether it was due to an impairment of proximal tubular endocytosis of filtered albumin. We st
Autor:
Franziska Theilig, Sebastian Bachmann, Robert Koesters, Danny Polzin, Anne Kathrin Enke, Brigitte Scolari
Publikováno v:
The American Journal of Pathology. 179:2177-2188
In many kidney diseases, the original insult primarily involves the glomerulus and may then pass onto the tubulointerstitium. Several hypotheses link glomerular disease to tubular injury; perhaps the foremost hypothesis involves chronic tubular hypox
Autor:
Marcus Pohl, Franziska Theilig, Nina Himmerkus, Sebastian Bachmann, Michael Bader, Henriette Josephine Kaminski, Hayo Castrop, Markus Bleich
Publikováno v:
Journal of Biological Chemistry. 285:41935-41946
The existence of a local renin angiotensin system (RAS) of the kidney has been established. Angiotensinogen (AGT), renin, angiotensin-converting enzyme (ACE), angiotensin receptors, and high concentrations of luminal angiotensin II have been found in
Autor:
Franziska Theilig, Wei Wang, Alain Vandewalle, Henriette Josephine Kaminski, Danny Polzin, Sebastian Bachmann, Christian Kastner, Michael Russwurm, Harm Peters, Stepan Gambaryan, Qingyu Wu, Stephanie Krämer
Publikováno v:
Kidney International. 78:650-659
Patients with proteinuric kidney diseases often have symptoms of salt and water retention. It has been hypothesized that dysregulated sodium absorption is due to increased proteolytic cleavage of epithelial sodium channels (ENaCs) and increased Na,K-
Autor:
Franziska Theilig, Wilhelm Kriz, Robert Koesters, Michel LeHir, Hiltraud Hosser, Nicolas Picard, Rolf Gebhardt, Brigitte Kaissling, Adam B. Glick, Brunhilde Hähnel, Hermann Josef Gröne
Publikováno v:
The American Journal of Pathology. 177:632-643
We recently showed in a tetracycline-controlled transgenic mouse model that overexpression of transforming growth factor (TGF)-beta1 in renal tubules induces widespread peritubular fibrosis and focal degeneration of nephrons. In the present study we
Autor:
Franziska Theilig
Publikováno v:
Annals of Anatomy - Anatomischer Anzeiger. 192:125-132
Chronic kidney disease is characterized by the decline in renal excretory, homeostatic and endocrine functions. In most instances, the primary event is glomerular injury. With ongoing progression and glomerular extracapillary proliferation, tubuloint
Autor:
Volker Henn, Friedrich W. Herberg, Michael Beyermann, Eduard Stefan, Walter Rosenthal, Burkhard Wiesner, Giovana Valenti, Sebastian Bachmann, Roland Schmitt, Dorothea Lorenz, Enno Klussmann, Eberhard Krause, Grazia Tamma, Franziska Theilig, Bayram Edemir, Lutz Vossebein
Publikováno v:
Journal of Biological Chemistry. 279:26654-26665
Arginine vasopressin (AVP) increases the water permeability of renal collecting duct principal cells by inducing the fusion of vesicles containing the water channel aquaporin-2 (AQP2) with the plasma membrane (AQP2 shuttle). This event is initiated b