Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daisuke Ogasawara"'
Autor:
Evan N. Graf, Elizabeth M. Doncheck, David A. Baker, Benjamin F. Cravatt, Cecilia J. Hillard, John R. Mantsch, Daisuke Ogasawara, Yan Li, Jayme R. McReynolds, Qing-song Liu, Oliver Vranjkovic
Publikováno v:
Biological Psychiatry. 84:85-94
Background Clinical reports suggest that rather than directly driving cocaine use, stress may create a biological context within which other triggers for drug use become more potent. We hypothesize that stress-induced increases in corticosterone “s
Autor:
Sally Miller, Alex Straiker, Laura Daily, Iwao Ojima, J Gertsch, Vijai Dharla, Michael S. Malamas, Martin Kaczocha, Daisuke Ogasawara
Publikováno v:
Exp Eye Res
Cannabinoids are part of an endogenous signaling system found throughout the body, including the eye. Hepler and Frank showed in the early 1970s that plant cannabinoids can lower intraocular pressure (IOP), an effect since shown to occur via cannabin
Autor:
Osamu Iida, Mitsuyoshi Takahara, Yoshimitsu Soga, Keisuke Hirano, Yasutaka Yamauchi, Kan Zen, Daizo Kawasaki, Shinsuke Nanto, Hiroyoshi Yokoi, Masaaki Uematsu, Nobuyoshi Azuma, Makoto Nakahama, Junichi Tazaki, Tsuyoshi Miyazawa, Masashi Fukunaga, Takahide Suzuki, Nobuhiro Suematsu, Yoshinori Tsubakimoto, Taketsugu Tsuchiya, Atsushi Tosaka, Kyozo Inoue, Terutoshi Yamaoka, Masatsugu Nakano, Michiaki Higashitani, Daisuke Ogasawara, Kenji Suzuki, Yoshiaki Shintani, Yusuke Miyashita, Norihiko Shinozaki, Makoto Utsunomiya, Hiroki Takahashi
Publikováno v:
JACC: Cardiovascular Interventions. 9:828-834
Objectives This study sought to investigate the characteristics of in-stent restenosis (ISR) after drug-eluting stent (DES) implantation for femoropopliteal (FP) lesions, and to examine 1-year prognosis after repeat endovascular therapy (re-EVT) for
Autor:
Hidenari Matsumoto, Daisuke Ogasawara, Satoshi Watanabe, Hideyuki Takaoka, Ryohei Yoshikawa, Mitsuhiro Yokoyama, Daisuke Matsumoto, Hiromasa Otake, Toshiro Shinke, Junya Shite, Toru Ozawa, Nobutaka Inoue, Ken-ichi Hirata
Publikováno v:
Journal of Cardiology. 66:232-238
Background Human atrial natriuretic peptide (hANP) and spontaneous nitric oxide (NO) donor share cyclic guanosine monophosphate (cGMP) as a second messenger, but their effect on myocardium may differ. We compared the effect of hANP and sodium nitropr
Autor:
Satoshi Watanabe, Hideyuki Takaoka, Daisuke Ogasawara, Hiromasa Otake, Junya Shite, Toshiro Shinke, Takahiro Sawada, Daisuke Matsumoto, Mitsuhiro Yokoyama, Yusuke Tanino, Ken-ichi Hirata
Publikováno v:
Journal of Cardiology. 58:245-252
Summary Objectives This study was designed to determine the prognostic importance of left ventricular (LV) myocardial stiffness, a hemodynamic index which is closely related to B-type natriuretic peptide (BNP) concentration in patients with congestiv
Autor:
Peter J. Fitzgerald, Yasuhiro Honda, Hiroki Kato, Junya Shite, Junya Ako, Yusuke Tanino, Daisuke Ogasawara, Toshiro Shinke, Bon-Kwon Koo, Takahiro Sawada, Ken-ichi Hirata, Naoki Miyoshi, Hiromasa Otake
Publikováno v:
JACC: Cardiovascular Interventions. 2(5):459-466
ObjectivesWe conducted this study to assess the prevalence and determinants of subclinical thrombus after sirolimus-eluting stent (SES) implantation.BackgroundAngioscopic analyses have demonstrated the presence of thrombus is more common than the cli
Autor:
Takahiro Sawada, Ken-ichi Hirata, Satoshi Watanabe, Mitsuhiro Yokoyama, Junya Shite, Yusuke Tanino, Daisuke Ogasawara, Toshiro Shinke, Hiromasa Otake
Publikováno v:
The American Journal of Cardiology. 101:1-7
The present study investigated the relation between plasma high-sensitivity C-reactive protein (hs-CRP) and adiponectin and coronary plaque components in patients with acute coronary syndrome (ACS). Previous studies showed a pivotal role of inflammat
Autor:
Osamu Iida, Mitsuyoshi Takahara, Yoshimitsu Soga, Keisuke Hirano, Yasutaka Yamauchi, Kan Zen, Hiroyoshi Yokoi, Masaaki Uematsu, Nobuyoshi Azuma, Makoto Nakahama, Junichi Tazaki, Tsuyoshi Miyazawa, Masashi Fukunaga, Takahide Suzuki, Nobuhiro Suematsu, Yoshinori Tsubakimoto, Taketsugu Tsuchiya, Atsushi Tosaka, Kyozo Inoue, Terutoshi Yamaoka, Daizo Kawasaki, Masatsugu Nakano, Michiaki Higashitani, Daisuke Ogasawara, Kenji Suzuki, Yoshiaki Shintani, Yusuke Miyashita, Norihiko Shinozaki, Makoto Utsunomiya, Hiroki Takahashi
Publikováno v:
Journal of Vascular Surgery. 64:1691-1695.e1
Objective Although clinical trials demonstrated the superiority of the Zilver (Cook Medical, Bloomington, Ind) paclitaxel-eluting stent (PTX), a recently developed drug-eluting stent (DES), to conventional therapy for femoropopliteal (FP) lesions, th
Autor:
Daisuke Ogasawara
Publikováno v:
Journal of the American College of Cardiology. 59(13)
Many reports suggest that peripheral artery disease (PAD) is closely related to metabolic risk factor and coronary artery disease (CAD). However, little is known of the substantial effect on peripheral artery plaque components. Fifty-eight lesions in
SYNTHESIS, LSD1 INHIBITORY ACTIVITY, AND LSD1 BINDING MODEL OF OPTICALLY PURE LYSINE-PCPA CONJUGATES
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 9, Iss 14, Pp 1-9 (2014)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Compounds that inhibit the catalytic function of lysine-specific demethylase 1 (LSD1) are interesting as therapeutic agents. Recently, we identified three lysine-phenylcyclopropylamine conjugates, NCD18, NCD25, and NCD41, which are potent LSD1 inacti