Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Li, Ying"'
Autor:
James D. Johnson, Nooshin Safikhan, Xiaowei Zheng, Jukka Laine, Mikael Rydén, Earl Albone, Christophe Noll, André C. Carpentier, Subashini Karunakaran, Timothy J. Kieffer, Michelle M. Kwon, Susanne M. Clee, Sergiu-Bogdan Catrina, Kirsi A. Virtanen, Jenny Li-Ying Huang, Tara L. Fernandez, Daniel J. O'Shannessy, Victor Lei, Edward M. Conway, Paul Petrus
Publikováno v:
EBioMedicine. 44:489-501
Background A positive energy balance promotes white adipose tissue (WAT) expansion which is characterized by activation of a repertoire of events including hypoxia, inflammation and extracellular matrix remodelling. The transmembrane glycoprotein CD2
Autor:
Xiujun Li, Rui Zeng, Li Ying, Yan Qu, Yanfang Li, Hengxiu Yan, Lixin Yang, Yuanping Gao, Xiaodong Ren, Chen Junke, Luyang Lv, Hao Luo
Publikováno v:
International Journal of Biological Macromolecules. 130:827-835
Uncontrolled bleeding is an important cause of military and civilian casualties. GO has received more attention in the field of hemostasis. However, pure GO has various limitation in application due to its potential thrombosis, hemolytic and cytotoxi
Publikováno v:
European Journal of Medicinal Chemistry. 151:849-860
Xanthine oxidase, which catalyzes the oxidative reaction of hypoxanthine and xanthine into uric acid, is a key enzyme to the pathogenesis of hyperuricemia and gout. In this study, for the purpose of discovering novel xanthine oxidase (XO) inhibitors,
Autor:
Yuyu Yang, Ping Li, Lin An, Jun Chen, Xuewen Hu, Ping Zhou, Li-Ying Peng, Yong Xu, Li Xueyan, Ning-Yuan Sun
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:882-890
NF-E2-related factor 2 (Nrf2) has been shown to be protective in atherosclerosis. The loss of Nrf2 in macrophages enhances foam cell formation and promotes early atherogenesis. Tanshindiol C (Tan C) is isolated from the root of Salvia miltiorrhiza Bg
Publikováno v:
Experimental Cell Research. 405:112662
The cytoophidium, a filamentous structure formed by metabolic enzymes, has emerged as a novel regulatory machinery for certain proteins. The rate-limiting enzymes of de novo CTP and GTP synthesis, cytidine triphosphate synthase (CTPS) and inosine mon
Autor:
Yuan-Chang Jin, Hai-Long Wang, Zhong-Feng Xu, Kang-Na Wei, Shu-Zi Deng, Shu-Hua Tan, Chang-Long Xu, Xiang-Jun Yang, Zhao-Cheng Zeng, Li-Ying Zhou, Shu-Juan Xie
Publikováno v:
Toxicology. 460:152884
Perfluorodecanoic acid (PFDA) is a member of the perfluoroalkyl substances, which are toxic to organic functions. Recently, it has been found in follicular fluid, seriously interfering with reproduction. Follicular fluid provides the oocyte with nece
Autor:
James E. Cox, Edward H. Schuchman, Li Ying, John Alan Maschek, Yoshio Hirabayashi, William L. Holland, Bhagirath Chaurasia, Scott A. Summers, Chad Lamar Talbot
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 45, Iss, Pp 101145-(2021)
Molecular Metabolism, Vol 45, Iss, Pp 101145-(2021)
Objective Aging and weight gain lead to a decline in brown and beige adipocyte functionality that exacerbates obesity and insulin resistance. We sought to determine whether sphingolipids, such as ceramides, a class of lipid metabolites that accumulat
Autor:
Fu-Tong Liu, I-Wen Song, Ya-Jen Chang, Chun-Chou Tsai, Li-Fen Shen, Jeffrey J.Y. Yen, Hsiao-Li Chuang, Li-Ying Chen, Hsin-Fang Yang-Yen, Yuan-Tsong Chen, Liang-Tung Yang, Christina Li-Ping Thio, Yen-Te Huang, Kai-Ming Liu
Publikováno v:
Journal of Investigative Dermatology. 137:894-904
Atopic dermatitis is a complex chronic inflammatory skin disorder that results from intimate interactions among genetic predisposition, host environment, skin barrier defects, and immunological factors. However, a clear genetic roadmap leading to ato
Publikováno v:
International Journal of Pharmaceutics. 511:831-839
To monitor the spatial distribution of embolic particles inside the target tissues during and after embolization, blank poly (acrylic acid) microspheres (PMs) were initially prepared by inverse suspension polymerization method and then loaded with su
Autor:
Xin-Hui Zhang, Yun-Peng Gong, Le-Min Jiao, Wen Zhao, Hong-Min Liu, Li-Ying Ma, Hui Qiao, Xin Zhang, Qi An, Jin-Ling Huo, Yang Feifei, Zhang-Xu He
Publikováno v:
European Journal of Medicinal Chemistry. 210:112970
To discover novel anticancer agents with potent and low toxicity, we designed and synthesized a range of new thiosemicarbazone-indole analogues based on lead compound 4 we reported previously. Most compounds displayed moderate to high anticancer acti