Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Hua Zhang"'
Autor:
Weike, Liu, Huajing, Song, Jing, Xu, Yuqi, Guo, Chunju, Zhang, Yanli, Yao, Hua, Zhang, Zhendong, Liu, Yue-Chun, Li
Publikováno v:
Atherosclerosis. 356:9-17
Mitophagy plays a crucial role in mitochondrial homeostasis and is closely associated with endothelial function. However, the mechanism underlying low blood flow shear stress (SS), detrimental cellular stress, regulating endothelial mitophagy is uncl
Publikováno v:
Atherosclerosis. 346:36-45
Vascular calcification (VC) is an intricate active process, significantly controlled by vascular smooth muscle cells (VSMCs). Mitochondrial dysfunction plays a pivotal role in VC and VSMCs osteoblastic transformation. We previously reported that decr
Autor:
Spencer K. Tumbale, R. Holland Cheng, Elizabeth S. Ingham, Wei-Lun Tang, Sarah M. Tam, Bo Wu, Alexander D. Borowsky, Katherine W. Ferrara, Mo Baikoghli, Marina Nura Raie, Brett Z. Fite, Josquin Foiret, Azadeh Kheirolomoom, Lisa M. Mahakian, Hua Zhang, Kenneth Lau
Publikováno v:
J Control Release
Resiquimod (R848) is a toll-like receptor 7 and 8 (TLR7/8) agonist with potent antitumor and immunostimulatory activity. However, systemic delivery of R848 is poorly tolerated because of its poor solubility in water and systemic immune activation. In
Autor:
Yan-Zhong Chang, Xue Bai, Guofen Gao, Peng Yu, Jian-Hua Zhang, Kang Han, Yong Xu, Zhenhua Shi, Yating Zhang, Linhao You, Xinwei Zhang
Publikováno v:
Free Radical Biology and Medicine. 158:84-95
Iron overload in the brain and iron-induced oxidative damage have been considered to play key roles in the pathogenesis of Alzheimer's disease (AD). Hepcidin is a peptide that regulates systemic iron metabolism by interacting with iron exporter ferro
Autor:
Mingzhe Zheng, Junna Jiao, Woodvine Otieno Odhiambo, Zhuangwei Lv, Xiaozhuo Yu, Meng Yuan, Yunfeng Ma, Ping Zhang, Yanhong Ji, Hua Zhang, Yang Wang
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 3, Pp 142-153 (2020)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 3, Pp 142-153 (2020)
The BCL6 proto-oncogene encodes a transcriptional repressor, which is required for germinal centers (GCs) formation and lymphomagenesis. Previous studies have been reported that the constitutive expression of BCL6 leads to diffuse large B cell lympho
Autor:
Sheng-Lei Song, Bo Li, Mariana R. Carvalho, Hui-Jin Wang, De-Li Mao, Ji-Tao Wei, Wei Chen, Zhi-Hui Weng, Yang-Chao Chen, Chu-Xia Deng, Rui L. Reis, Joaquim M. Oliveira, Yu-Long He, Le-Ping Yan, Chang-Hua Zhang
Publikováno v:
Pharmacology & Therapeutics. 239:108276
Digestive system cancers account for nearly half of all cancers around the world and have a high mortality rate. Cell culture and animal models represent cornerstones of digestive cancer research. However, their ability to en- able cancer precision m
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 259:109389
Inflammatory chemokine CCL5 can mediate the occurrence of inflammatory reactions and participate in various disease processes. (Ch)CCL5 gene of Jintang black goat (Capra hircus, C. hircus) was cloned. The CDS (coding sequences) was 276 bp in length a
Autor:
Zhen-Feng Wang, Xiao-Feng Zhou, Qiao-Chang Wei, Qi-Pin Qin, Jin-Xian Li, Ming-Xiong Tan, Shu-Hua Zhang
Publikováno v:
European Journal of Medicinal Chemistry. 238:114418
Four novel bifluorescent Zn(II)-cryptolepine-cyclen complexes, namely [Zn(BQTC)]Cl
Autor:
Feng-ting Yin, Xiao-hang Zhou, Shu-yu Kang, Xing-hua Li, Jing Li, Ihsan Ullah, Ai-hua Zhang, Hui Sun, Xi-jun Wang
Publikováno v:
Journal of Ethnopharmacology. 293:115286
Colorectal cancer (CRC) is a common digestive tract malignant tumor that its morbidity and mortality seriously affect human health. At present, Dachengqi Decoction (DCQ), a traditional Chinese medicine formula, has been clinically used as an adjuvant
Autor:
Philip N. Baker, Xinyang Yu, Hua Zhang, Hongbo Qi, Ting-Li Han, Andi Wang, Xiaobo Zhou, Chen Zhu
Publikováno v:
Experimental Cell Research. 381:29-38
Maternal obesity is associated with adverse effects on the health of offsprings. Consumption of a high-carbohydrate (HC) diet has been found to promote abnormal fatty acid metabolism in adipose tissue. Therefore, we hypothesised that maternal obesity